[1]符瑶,尹晓.神经降压素在肥胖症和糖尿病中的作用及机制研究进展[J].陕西医学杂志,2026,(6):861-864，封三.[doi:DOI:10.3969/j.issn.1000-7377.2026.06.024]
　FU Yao,YIN Xiao.Research advances on role and mechanism of neurotensin in obesity and diabetes[J].,2026,(6):861-864，封三.[doi:DOI:10.3969/j.issn.1000-7377.2026.06.024]
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神经降压素在肥胖症和糖尿病中的作用及机制研究进展

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2026年6期
页码:
861-864，封三
栏目:
综述
出版日期:
2026-06-05

文章信息/Info

Title:
Research advances on role and mechanism of neurotensin in obesity and diabetes
作者:
符瑶1; 尹晓2
（1.山东第二医科大学临床医学院，山东 潍坊 261053；2.中日友好医院内分泌科，北京 100029）
Author(s):
FU Yao1; YIN Xiao2
(1.School of Clinical Medicine，Shandong Second Medical University，Weifang 261053，China;2.Department of Endocrinology，China-Japan Friendship Hospital，Beijing 100029，China)
关键词:
肥胖症; 糖尿病; 神经降压素; 生物标志物; 神经降压素受体1; 肠-脑轴
Keywords:
Obesity; Diabetes; Neurotensin; Biomarker; Neurotensin receptor 1; Gut-brain axis
分类号:
R 58
DOI:
DOI:10.3969/j.issn.1000-7377.2026.06.024
文献标志码:
A
摘要:
肥胖症与糖尿病的发病率逐年攀升，两者紧密关联，已成为重大公共卫生问题。神经降压素(NT)作为一种广泛分布于中枢神经系统与胃肠道的生物活性肽，参与能量代谢、摄食行为等多条调节通路，生理功能复杂且具有高度的组织特异性。本文系统阐述了神经NT的生理学功能，并综述其在肥胖与糖尿病中的作用及机制研究进展，旨在为该领域的深入研究提供思路与参考。
Abstract:
Obesity and diabetes have been rising in prevalence year by year，and their close association has become a major public health issue.Neurotensin(NT)，a bioactive peptide widely distributed in the central nervous system and the gastrointestinal tract，participates in multiple regulatory pathways such as energy metabolism and feeding behavior;its physiological functions are complex and exhibit a high degree of tissue specificity.This article systematically describes the physiological functions of neurotensin and reviews its role and the latest research advances in obesity and diabetes，aiming to provide ideas and references for for further research in this field.

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备注/Memo

备注/Memo:
山东省自然科学基金资助面上项目（ZR2021MH204）
更新日期/Last Update: 2026-06-05