[1]董 盼,盛 月,张 荷,等.经导管动脉硬化栓塞联合局部注射治疗口腔颌面部巨大血管瘤临床价值研究[J].陕西医学杂志,2026,(5):633-638.[doi:DOI:10.3969/j.issn.1000-7377.2026.05.010]
　DONG Pan,SHENG Yue,ZHANG He,et al.Clinical value of transcatheter arteriosclerotic embolization combined with local injection in the treatment of giant hemangiomas of the oral and maxillofacial region[J].,2026,(5):633-638.[doi:DOI:10.3969/j.issn.1000-7377.2026.05.010]
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经导管动脉硬化栓塞联合局部注射治疗口腔颌面部巨大血管瘤临床价值研究

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2026年5期
页码:
633-638
栏目:
临床研究
出版日期:
2026-05-05

文章信息/Info

Title:
Clinical value of transcatheter arteriosclerotic embolization combined with local injection in the treatment of giant hemangiomas of the oral and maxillofacial region
作者:
董 盼1; 盛 月2; 张 荷1; 刘怡晨1; 崖 骞1
（1.山西医科大学附属运城市中心医院整形外科，山西 运城 044000；2.杭州口腔医院，浙江 杭州 310006）
Author(s):
DONG Pan1; SHENG Yue2; ZHANG He1; LIU Yichen1; YA Qian1
(1.Department of Plastic Surgery,Yuncheng Central Hospital Affiliated to Shanxi Medical University,Yuncheng 044000,China;2.Hangzhou Stomatology Hospital,Hangzhou 310006,China)
关键词:
口腔颌面部血管瘤; 经导管动脉硬化栓塞术; 无水酒精; 聚桂醇; 复发; 安全性
Keywords:
Oral and maxillofacial hemangioma; Transcatheter arteriosclerotic embolization; Absolute ethanol; Lauromacrogol; Recurrence; Safety
分类号:
R739.8
DOI:
DOI:10.3969/j.issn.1000-7377.2026.05.010
文献标志码:
A
摘要:
目的：探讨经导管动脉硬化栓塞联合局部注射无水酒精或聚桂醇治疗口腔颌面部巨大血管瘤的临床价值。方法：选取168例口腔颌面部巨大血管瘤患者，根据治疗方案分为联合治疗组（经导管动脉硬化栓塞术联合序贯超声引导下无水酒精或聚桂醇硬化治疗，92例）和单纯栓塞组（经导管动脉硬化栓塞术治疗，76例）。比较两组患者基线资料、治疗次数及症状缓解时间、瘤体体积缩小率、临床疗效、并发症发生情况及复发情况。结果：联合治疗组与单纯栓塞组年龄、性别、瘤体最大径、术前瘤体体积、病变部位及血流动力学分型等基线资料比较无统计学差异（均P>0.05）。两组栓塞治疗次数比较差异无统计学意义（P>0.05）。联合治疗组疼痛及肿胀缓解时间短于单纯栓塞组（均P<0.05）。联合治疗组治疗后1、3、6个月瘤体体积缩小率高于单纯栓塞组（均P<0.05）。联合治疗组总有效率、显效率高于单纯栓塞组（均P<0.05）。两组栓塞后综合征、局部肿胀加重、一过性神经麻木及并发症总发生率比较差异无统计学意义（均P>0.05）。联合治疗组复发率较单纯栓塞组降低，但差异无统计学意义（P>0.05）。结论：经导管动脉硬化栓塞联合局部无水酒精或聚桂醇注射治疗口腔颌面部巨大血管瘤疗效较好，能够更快缩小瘤体、缓解症状，有降低远期复发的趋势，且安全性较高。
Abstract:
Objective:To explore the clinical value of transcatheter arteriosclerotic embolization combined with local injection of absolute ethanol or lauromacrogol in the treatment of giant hemangiomas of the oral and maxillofacial region.Methods：A total of 168 patients with giant oral and maxillofacial hemangiomas were enrolled and divided into two groups according to the treatment plan：the combined treatment group (transcatheter arteriosclerotic embolization combined with sequential ultrasound-guided absolute ethanol or lauromacrogol sclerotherapy,92 cases) and the simple embolization group (transcatheter arteriosclerotic embolization alone,76 cases).Baseline data,number of treatments,symptom relief time,tumor volume reduction rate,clinical efficacy,occurrence of complications and recurrence were compared between the two groups.Results:There were no significant differences in baseline data such as age,gender,maximum tumor diameter,preoperative tumor volume,lesion location and hemodynamic classification between the combined treatment group and the simple embolization group (all P>0.05).There was no significant difference in the number of embolization treatments between the two groups (P>0.05).The relief time of pain and swelling in the combined treatment group was shorter than that in the simple embolization group (all P<0.05).The tumor volume reduction rate of the combined treatment group at 1,3 and 6 months after treatment was higher than that of the simple embolization group (all P<0.05).The total effective rate and marked effective rate of the combined treatment group were higher than those of the simple embolization group (all P<0.05).There were no significant differences in the incidence of post-embolization syndrome,aggravated local swelling,transient numbness of nerves and total incidence of complications between the two groups (all P>0.05).The recurrence rate of the combined treatment group was lower than that of the simple embolization group,but the difference was not statistically significant (P>0.05).Conclusion:Transcatheter arteriosclerotic embolization combined with local injection of absolute ethanol or lauromacrogol has a good curative effect in the treatment of giant oral and maxillofacial hemangiomas.It can shrink the tumor faster,relieve symptoms,has a tendency to reduce long-term recurrence,and has high safety.

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备注/Memo

备注/Memo:
山西省自然科学基金资助项目（2025RZS-120351）
更新日期/Last Update: 2026-05-05