[1]梁晓芳,李晓利,张占华,等.社区获得性肺炎患者中性粒细胞/淋巴细胞比值和血小板/淋巴细胞比值水平及意义[J].陕西医学杂志,2026,(4):546-549.[doi:DOI:10.3969/j.issn.1000-7377.2026.04.020]
　LIANG Xiaofang,LI Xiaoli,ZHANG Zhanhua,et al.The Levels and Significance of NLR and PLR in Patients with CommunityAcquired Pneumonia[J].,2026,(4):546-549.[doi:DOI:10.3969/j.issn.1000-7377.2026.04.020]
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社区获得性肺炎患者中性粒细胞/淋巴细胞比值和血小板/淋巴细胞比值水平及意义

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2026年4期
页码:
546-549
栏目:
临床检验
出版日期:
2026-04-05

文章信息/Info

Title:
The Levels and Significance of NLR and PLR in Patients with CommunityAcquired Pneumonia
作者:
梁晓芳; 李晓利; 张占华; 卫尧; 荀梅
（西安交通大学附属红会医院，陕西 西安 710000）
Author(s):
LIANG Xiaofang; LI Xiaoli; ZHANG Zhanhua; WEI Yao; XUN Mei
（Honghui Hospital Affiliated to Xi’an Jiaotong University,Xi’an 710000,China）
关键词:
中性粒细胞/淋巴细胞比值; 血小板/淋巴细胞比值; 社区获得性肺炎; 应用价值; 成人
Keywords:
Neutrophil/lymphocyte ratio; Platelet/lymphocyte ratio; Community acquired pneumonia; Application value; Adult
分类号:
R 563.1
DOI:
DOI:10.3969/j.issn.1000-7377.2026.04.020
文献标志码:
A
摘要:
目的：探讨中性粒细胞/淋巴细胞比值（NLR）和血小板/淋巴细胞比值（PLR）在成人社区获得性肺炎中的应用价值。方法：采用回顾性研究方法，选取治疗的成人社区获得性肺炎患者300例，根据患者治疗后28 d生存情况分为生存组（272例）和死亡组（28例），分析生存组和死亡组患者临床资料差异。结果：死亡组患者年龄≥60岁，占比为53.57%，高于生存组（P＜0.05）；死亡组患者重症占比为57.14%，高于生存组（P＜0.05）；死亡组患者NLR、PLR分别为（9.10±1.41）和（202.23±43.52），高于生存组（均P＜0.05）；细菌性肺炎患者NLR和PLR明显高于病毒性和支原体肺炎（均P＜0.05）；支原体肺炎患者NLR和PLR明显高于病毒性肺炎（均P＜0.05）；Logistic回归分析，结果显示：年龄、严重程度、NLR和PLR是患者死亡的影响因素（均P＜0.05）；NLR、PLR预测患者预后的ROC曲线下面积分别为0.904（95%CI：0.854～0.954）和0.708（95%CI：0.621～0.795）（均P＜0.05），截断值分别为8.10和187.84，灵敏度分别为78.60%和64.30%，特异度分别为91.20%和72.40%。结论：NLR和PLR是成人社区获得性肺炎患者预后的影响因素，其中NLR预测预后的价值较高。
Abstract:
Objective:Toexplore the application value of neutrophil/lymphocyte ratio （NLR） and platelet/lymphocyte ratio （PLR） in adult community acquired pneumonia.Methods：A retrospective study method were used,300 adult patients with communityacquired pneumonia who were treated in our hospital from January 2022 to January 2025 were selected,they were divided into a survival group （272 cases） and a death group （28 cases） based on their 28 day survival after treatment,the clinical data differences between the survival group and the death group were analyzed.Results:The proportion of patients with age ≥ 60 years old and severe cases in the death group was 53.57%,which were higher than that in the survival group （P<0.05）.The proportion of patients with severe cases in the death group was 57.14%,which were higher than that in the survival group （P<0.05）.The NLR and PLR of patients in the death group were （9.10±1.41） and （202.23±43.52）,respectively,which were higher than those in the survival group （all P<0.05）.The NLR and PLR of patients with bacterial pneumonia were significantly higher than those with viral and mycoplasma pneumonia （all P<0.05）.The NLR and PLR of patients with mycoplasma pneumonia were significantly higher than those with viral pneumonia （all P<0.05）.Logistic regression analysis showed that age,severity,NLR,and PLR were the influencing factors for patient mortality （all P<0.05）.The area under the ROC curve for predicting patient prognosis by NLR and PLR was 0.904 （95%CI：0.854~0.954） and 0.708 （95%CI：0.621~0.795）,respectively,P<0.05,cutoff values were 8.10 and 187.84,sensitivity were 78.60% and 64.30%,specificity were 91.20% and 72.40%,respectively.The proportion of patients aged ≥ 60 years in the severe group was 58.43%,which was higher than that in the mild group （all P<0.05）.Conclusion:NLR and PLR are influencing factors for the prognosis of adult community acquired pneumonia patients,with NLR having higher predictive value.

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备注/Memo

备注/Memo:
陕西省自然科学基础研究计划项目（2021JM576）
更新日期/Last Update: 2026-04-05