参考文献/References:
[1] YANG J,LI Q.Rheumatoid arthritis[J].N Engl J Med,2023,388(20):1919.
[2] 张晓华,王利,刘丹,等.艾拉莫德治疗活动性类风湿关节炎合并骨量低下疗效及对患者骨代谢及外周血免疫指标的影响研究[J].陕西医学杂志,2021,50(4):482-484.
[3] BROCK J,BASU N,SCHLACHETZKI J C M,et al.Immune mechanisms of depression in rheumatoid arthritis[J].Nat Rev Rheumatol,2023,19(12):790-804.
[4] 李凌巍,秦俊杰,贾云龙,等.孟德尔随机化在肝癌研究中的应用[J].临床肝胆病杂志,2024,40(2):391-396.
[5] BAE S C,LEE Y H.Causal association between body mass index and risk of rheumatoid arthritis:A Mendelian randomization study[J].Eur J Clin Invest,2019,49(4):e13076.
[6] 尚文茹,魏莉莉,卢存存.受教育程度对系统性红斑狼疮的因果效应:孟德尔随机化研究[J].华西医学,2023,38(12):1880-1884.
[7] 周星宇,崔家禾,张玉飞,等.强直性脊柱炎可能增加精神障碍的风险:基于两样本孟德尔随机化方法[J].重庆医科大学学报,2023,48(12):1462-1469.
[8] KATAN M B.Apoupoprotein E isoforms,serum cholesterol,and cancer[J].The Lancet,1986,1(8479):507-508.
[9] SOMMER F,BÄCKHED F.The gut microbiota-masters of host development and physiology[J].Nat Rev Microbiol,2013,11(4):227-238.
[10] THOMAS S,IZARD J,WALSH E,et al.The host microbiome regulates and maintains human health:A primer and perspective for non-microbiologists[J].Cancer Res,2017,77(8):1783-1812.
[11] HONDA K,LITTMAN D R.The microbiota in adaptive immune homeostasis and disease[J].Nature,2016,535(7610):75-84.
[12] SCHRIJVER I A,MELIEF M J,TAK P P,et al.Antigen-presenting cells containing bacterial peptidoglycan in synovial tissues of rheumatoid arthritis patients coexpress costimulatory molecules and cytokines[J].Arthritis Rheum,2000,43(10):2160-2168.
[13] PIANTA A,ARVIKAR S,STRLE K,et al.Evidence of the immune relevance of Prevotella copri,a gut microbe,in patients with rheumatoid arthritis[J].Arthritis Rheumatol,2017,69(5):964-975.
[14] KINASHI Y,HASE K.Partners in leaky gut syndrome:Intestinal dysbiosis and autoimmunity[J].Front Immunol,2021,12:673708.
[15] CHEN B,SUN L,ZHANG X.Integration of microbiome and epigenome to decipher the pathogenesis of autoimmune diseases[J].J Autoimmun,2017,83:31-42.
[16] ZHANG X,ZHANG D,JIA H,et al.The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment[J].Nat Med,2015,21(8):895-905.
[17] JUNG H,JUNG S M,RIM Y A,et al.Arthritic role of Porphyromonas gingivalis in collagen-induced arthritis mice[J].PLoS One,2017,12(11):e0188698.
[18] FERREIRA-HALDER C V,FARIA A V S,ANDRADE S S.Action and function of Faecalibacterium prausnitzii in health and disease[J].Best Pract Res Clin Gastroenterol,2017,31(6):643-648.
[19] ILJAZOVIC A,ROY U,GÁLVEZ E J C,et al.Perturbation of the gut microbiome by Prevotella spp.enhances host susceptibility to mucosal inflammation[J].Mucosal Immunol,2021,14(1):113-124.
[20] AMDEKAR S,SINGH V,KUMAR A,et al.Lactobacillus casei and Lactobacillus acidophilus regulate inflammatory pathway and improve antioxidant status in collagen-induced arthritic rats[J].J Interferon Cytokine Res,2013,33(1):1-8.
[21] ALPIZAR-RODRIGUEZ D,LESKER T R,GRONOW A,et al.Prevotella copri in individuals at risk for rheumatoid arthritis[J].Ann Rheum Dis,2019,78(5):590-593.
[22] FLANNIGAN K L,DENNING T L.Segmented filamentous bacteria-induced immune responses:A balancing act between host protection and autoimmunity[J].Immunology,2018,154(4):537-546.
[23] WANG Y,YIN Y,CHEN X,et al.Induction of intestinal Th17 cells by flagellins from segmented filamentous bacteria[J].Front Immunol,2019,10:2750.
[24] ATARASHI K,TANOUE T,ANDO M,et al.Th17 cell induction by adhesion of microbes to intestinal epithelial cells[J].Cell,2015,163(2):367-380.
[25] CHEN J,WRIGHT K,DAVIS J M,et al.An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis[J].Genome Med,2016,8(1):43.
[26] GOU Y,ZHANG J,LI C,et al.Causal relationship between gut microbiota and rheumatoid arthritis:A two-sample Mendelian randomisation study[J].Clin Exp Rheumatol,2024,42(1):166-173.
[27] 邹晓荣,苏瑞,李芳,等.间充质干细胞对类风湿关节炎的免疫调节作用研究进展[J].空军军医大学学报,2022,43(3):365-370,375.
[28] 张娜,唐华燕.生地苦参汤联合艾拉莫德对类风湿性关节炎患者血清抗CCP抗体及炎症因子的影响[J].陕西中医,2022,43(3):318-320,341.
[29] MAHAGNA H,CAPLAN A,WATAD A,et al.Rheumatoid arthritis and thyroid dysfunction:A cross-sectional study and a review of the literature[J].Best Pract Res Clin Rheumatol,2018,32(5):683-691.
[30] LIU Y J,MIAO H B,LIN S,et al.Association between rheumatoid arthritis and thyroid dysfunction:A meta-analysis and systematic review[J].Front Endocrinol(Lausanne),2022,13:1015516.
[31] LI Q,WANG B,MU K,et al.Increased risk of thyroid dysfunction among patients with rheumatoid arthritis[J].Front Endocrinol(Lausanne),2019,9:799.
[32] DUAN L,CHEN D,SHI Y,et al.Rheumatoid arthritis and hypothyroidism:A bidirectional Mendelian randomization study[J].Front Immunol,2023,14:1146261.
[33] ZHAO S S,HOLMES M V,ZHENG J,et al.The impact of education inequality on rheumatoid arthritis risk is mediated by smoking and body mass index:Mendelian randomization study[J].Rheumatology(Oxford),2022,61(5):2167-2175.
[34] CALIXTO O J,ANAYA J M.Socioeconomic status.The relationship with health and autoimmune diseases[J].Autoimmun Rev,2014,13(6):641-654.
[35] JOHANSSON K,ASKLING J,ALFREDSSON L,et al.Mediterranean diet and risk of rheumatoid arthritis:A population-based case-control study[J].Arthritis Res Ther,2018,20(1):175.
[36] ROSELL M,WESLEY A M,RYDIN K,et al.Dietary fish and fish oil and the risk of rheumatoid arthritis[J].Epidemiology,2009,20(6):896-901.
[37] SONG G G,BAE S C,LEE Y H.Association between vitamin D intake and the risk of rheumatoid arthritis:A meta-analysis[J].Clin Rheumatol,2012,31(12):1733-1739.
[38] PHILIPPOU E,NIKIPHOROU E.Are we really what we eat? Nutrition and its role in the onset of rheumatoid arthritis[J].Autoimmun Rev,2018,17(11):1074-1077.
[39] QIN B,YANG M,FU H,et al.Body mass index and the risk of rheumatoid arthritis:A systematic review and dose-response meta-analysis[J].Arthritis Res Ther,2015,17(1):86.
[40] MINIHANE A M,VINOY S,RUSSELL W R,et al.Low-grade inflammation,diet composition and health:Current research evidence and its translation[J].Br J Nutr,2015,114(7):999-1012.
[41] GIOIA C,LUCCHINO B,TARSITANO M G,et al.Dietary habits and nutrition in rheumatoid arthritis:Can diet influence disease development and clinical manifestations?[J].Nutrients,2020,12(5):1456.
[42] NICKLAS T A,O'NEIL C E,ZANOVEC M,et al.Contribution of beef consumption to nutrient intake,diet quality,and food patterns in the diets of the US population[J].Meat Sci,2012,90(1):152-158.
[43] O'NEIL C E,ZANOVEC M,KEAST D R,et al.Nutrient contribution of total and lean beef in diets of US children and adolescents:National health and nutrition examination survey 1999-2004[J].Meat Sci,2011,87(3):250-256.
[44] PATTISON D J,SYMMONS D P,LUNT M,et al.Dietary risk factors for the development of inflammatory polyarthritis:Evidence for a role of high level of red meat consumption[J].Arthritis Rheum,2004,50(12):3804-3812.
[45] CHEN W,LIU K,HUANG L,et al.Beef intake and risk of rheumatoid arthritis:Insights from a cross-sectional study and two-sample Mendelian randomization[J].Front Nutr,2022,9:923472.
[46] CHEN Y,QIU F,YU B,et al.Metformin,an AMPK activator,inhibits activation of FLSs but promotes HAPLN1 secretion[J].Mol Ther Methods Clin Dev,2020,17:1202-1214.
[47] KIM E K,MIN H K,LEE S Y,et al.Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome[J].Arthritis Res Ther,2020,22(1):77.
[48] GHARIB M,ELBAZ W,DARWEESH E,et al.Efficacy and safety of metformin use in rheumatoid arthritis:A randomized controlled study[J].Front Pharmacol,2021,12:726490.
[49] CHEN K,LIN Z W,HE S M,et al.Metformin inhibits the proliferation of rheumatoid arthritis fibroblast-like synoviocytes through IGF-IR/PI3K/AKT/m-TOR pathway[J].Biomed Pharmacother,2019,115:108875.
[50] NAFFAA M,ROSENBERG V,WATAD A,et al.Adherence to metformin and the onset of rheumatoid arthritis:A population-based cohort study[J].Scand J Rheumatol,2020,49(3):173-180.[51] LU C H,CHUNG C H,LEE C H,et al.Combination of COX-2 inhibitor and metformin attenuates rate of admission in patients with rheumatoid arthritis and diabetes in Taiwan[J].Medicine(Baltimore),2019,98(41):e17371.[52] ZEMEDIKUN D T,GOKHALE K,CHANDAN J S,et al.Type 2 diabetes mellitus,glycaemic control,associated therapies and risk of rheumatoid arthritis:A retrospective cohort study[J].Rheumatology(Oxford),2021,60(12):5567-5575.[53] LIANG J,CAI Y,ZHANG J,et al.Metformin treatment reduces the incidence of rheumatoid arthritis:A two-sample Mendelian randomized study[J].J Clin Med,2023,12(7):2461.[54] WAN X,XIE J,YANG M,et al.Does having rheumatoid arthritis increase the dose of depression medications? A Mendelian randomization study[J].J Clin Med,2023,12(4):1405.[55] LI B,XIAO Y,XING D,et al.Circulating interleukin-6 and rheumatoid arthritis:A Mendelian randomization meta-analysis[J].Medicine(Baltimore),2016,95(23):e3855.[56] YUAN S,LI X,LIN A,et al.Interleukins and rheumatoid arthritis:Bi-directional Mendelian randomization investigation[J].Semin Arthritis Rheum,2022,53:151958.
相似文献/References:
[1]卢北玲,史剑飞,彭 晶,等.CRP、RF及ASO检测在类风湿关节炎合并肺间质纤维化诊断中的价值[J].陕西医学杂志,2019,(6):803.
[2]孙芳芳,张 静△,范秀风.类风湿关节炎合并心血管损伤危险因素研究*[J].陕西医学杂志,2019,(10):1305.
[3]王 颖,白 琳,张 洁,等.抑制炎性细胞因子与类风湿关节炎合并急性心肌梗死患者颈动脉斑块相关性研究*[J].陕西医学杂志,2019,(12):1679.
[4]刘昌莲,贺冬冬,李晓明,等.艾拉莫德治疗类风湿关节炎疗效及对患者免疫炎症因子水平和骨代谢指标的影响*[J].陕西医学杂志,2020,49(5):603.
LIU Changlian,HE Dongdong,LI Xiaoming,et al.Clinical efficacy of Iguratimod in the treatment of rheumatoid arthritis and its effect on the levels of immune inflammatory factors and the indexes of bone metabolism[J].,2020,49(11):603.
[5]刘兆宜,沈洲立,岳跃兵,等.类风湿关节炎并发动脉粥样硬化相关性研究进展*[J].陕西医学杂志,2020,49(11):1534.[doi:DOI:10.3969/j.issn.1000-7377.2020.11.043]
LIU Zhaoyi,SHEN Zhouli,YUE Yuebing,et al.Research progress on the correlation between rheumatoid arthritis and atherosclerosis[J].,2020,49(11):1534.[doi:DOI:10.3969/j.issn.1000-7377.2020.11.043]
[6]李长超,柴艳梅,刘 丹,等.类风湿关节炎患者血清IL-13水平表达及对外周血单个核细胞中Th17细胞亚群分化的影响[J].陕西医学杂志,2021,50(2):197.[doi:DOI:10.3969/j.issn.1000-7377.2021.02.018]
LI Changchao,CHAI Yanmei,LIU Dan,et al.Expression of serum IL-13 in patients with rheumatoid arthritis and its effect on differentiation of Th17 cell subsets in PBMC[J].,2021,50(11):197.[doi:DOI:10.3969/j.issn.1000-7377.2021.02.018]
[7]安 新,冯 超,高利常.类风湿关节炎患者血清白细胞介素-32、白细胞介素-17和白细胞介素-10表达水平及临床意义[J].陕西医学杂志,2021,50(12):1585.[doi:DOI:10.3969/j.issn.1000-7377.2021.12.030]
AN Xin,FENG Chao,GAO Lichang.Expression levels of serum interleukin-32,interleukin-17 and interleukin-10 in patients with rheumatoid arthritis and their clinical significance[J].,2021,50(11):1585.[doi:DOI:10.3969/j.issn.1000-7377.2021.12.030]
[8]杨 婧,何家锐,孙红兵,等.沙利度胺对类风湿关节炎滑膜细胞及外周血单个核细胞分泌肿瘤坏死因子-α和血管内皮生长因子的影响及机制研究[J].陕西医学杂志,2022,51(12):1501.[doi:DOI:10.3969/j.issn.1000-7377.2022.12.008]
YANG Jing,HE Jiarui,SUN Hongbing,et al.Effects of thalidomide on secretion of TNF-α and VEGF in fibroblast-like synoviocytes and peripheral blood mononuclear cells in patients with rheumatoid arthritis and its mechanism[J].,2022,51(11):1501.[doi:DOI:10.3969/j.issn.1000-7377.2022.12.008]
[9]王小蕊,李文倩,解友邦,等.托法替尼联合传统DMARDs类药物治疗类风湿性关节炎临床效果观察[J].陕西医学杂志,2023,52(12):1728.[doi:DOI:10.3969/j.issn.1000-7377.2023.12.022]
WANG Xiaorui,LI Wenqian,XIE Youbang,et al.Clinical effect of tofacitinib combined with traditional DMARDs in treatment of rheumatoid arthritis[J].,2023,52(11):1728.[doi:DOI:10.3969/j.issn.1000-7377.2023.12.022]
[10]康 聪,杨 光,王 芳,等.牛膝多糖调控转移相关蛋白1/核因子-κB通路对类风湿关节炎大鼠踝关节破坏的影响实验研究[J].陕西医学杂志,2024,(12):1624.[doi:DOI:10.3969/j.issn.1000-7377.2024.12.007]
KANG Cong,YANG Guang,WANG Fang,et al.Effects of achyranthan polysaccharides regulating MTA1/NF-κB pathway on destruction of ankle joint in rats with rheumatoid arthritis[J].,2024,(11):1624.[doi:DOI:10.3969/j.issn.1000-7377.2024.12.007]