[1]井 琳,闫洪超,陈忆云.人工助孕孕晚期流产与多囊卵巢综合征和宫颈机能关系研究[J].陕西医学杂志,2024,(10):1366-1370.[doi:DOI:10.3969/j.issn.1000-7377.2024.10.015]
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人工助孕孕晚期流产与多囊卵巢综合征和宫颈机能关系研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2024年10期
页码:
1366-1370
栏目:
临床研究
出版日期:
2024-10-05

文章信息/Info

作者:
井 琳1; 闫洪超2; 陈忆云3
(1.徐州医科大学研究生院妇产科,江苏 徐州 221000; 2.徐州医科大学附属医院妇产科,江苏 徐州 221000; 3.南京鼓楼医院集团宿迁医院平安路院区妇产科,江苏 宿迁223800)
关键词:
人工助孕;  妊娠;  孕晚期;  流产;  多囊卵巢综合征;  子宫机能不全;  危险因素
分类号:
R 714.2
DOI:
DOI:10.3969/j.issn.1000-7377.2024.10.015
文献标志码:
A
摘要:
目的: 探讨人工助孕孕晚期流产与多囊卵巢综合征(PCOS)、宫颈机能不全的关系。方法: 采取自身病例对照研究方法,选择实施人工助孕且成功妊娠的患者120例进行回顾性分析,其中31例出现孕晚期流产(流产组),另外89例未出现孕晚期流产(非流产组),对比两组的PCOS合并率、宫颈机能不全发生率、生殖激素水平,并建立多元Logistic回归模型分析引起人工助孕孕晚期流产的危险因素。结果:流产组孕妇的PCOS发病率、宫颈机能不全率均高于非流产组,流产组的子宫平均径线小于非流产组,差异具有统计学意义(均P<0.05); 流产组孕妇的宫颈环形电切术(LEEP)或锥切术史占比、宫腔镜下电切术史占比均高于非流产组,差异具有统计学意义(均P<0.05); 流产组孕妇的血清睾酮(T)水平、促黄体生成素(LH)水平高于非流产组,流产组孕妇的血清促卵泡刺激素(FSH)水平低于非流产组,差异具有统计学意义(均P<0.05); 流产组孕妇的妊娠糖尿病发病率、妊娠高血压发病率高于非流产组,流产组孕妇孕期服用叶酸率低于非流产组,差异具有统计学意义(均P<0.05); Logistic回归模型结果显示:合并PCOS、宫颈机能不全、具有LEEP或锥切术史是人工助孕孕妇发生晚期流产的独立危险因素(均P<0.05)。结论:合并PCOS、宫颈机能不全、具有LEEP或锥切术史会增大人工助孕孕晚期流产发生的风险。

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备注/Memo

备注/Memo:
基金项目:江苏省卫生计划生育委员会医学科研课题(20180115)
更新日期/Last Update: 2024-10-08