[1]姚 溪,侯敏娜,岳 芳,等.乳腺癌改良根治术患者近端肋间臂神经联合前锯肌平面阻滞临床效果观察[J].陕西医学杂志,2024,(9):1228-1231,1235.[doi:DOI:10.3969/j.issn.1000-7377.2024.09.016]
 YAO Xi,HOU Minna,YUE Fang,et al.Clinical effect of proximal intercostobrachial nerve combined with serratus anterior plane block in patients undergoing modified radical mastectomy for breast cancer[J].,2024,(9):1228-1231,1235.[doi:DOI:10.3969/j.issn.1000-7377.2024.09.016]
点击复制

乳腺癌改良根治术患者近端肋间臂神经联合前锯肌平面阻滞临床效果观察
分享到:

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2024年9期
页码:
1228-1231,1235
栏目:
临床研究
出版日期:
2024-09-05

文章信息/Info

Title:
Clinical effect of proximal intercostobrachial nerve combined with serratus anterior plane block in patients undergoing modified radical mastectomy for breast cancer
作者:
姚 溪侯敏娜岳 芳郭 姣
(陕西省人民医院麻醉科,陕西 西安 710068)
Author(s):
YAO XiHOU MinnaYUE FangGUO Jiao
(Department of Anesthesiology,Shaanxi Provincial People's Hospital,Xi'an 710068,China)
关键词:
乳腺癌改良根治术 近端肋间臂神经阻滞 前锯肌平面阻滞 术后疼痛 超声引导 阿片类药物
Keywords:
Modified radical mastectomy Proximal intercostobrachial nerve block Serratus anterior plane block Postoperative analgesia Ultrasonic guidance Opioids
分类号:
R 614.4
DOI:
DOI:10.3969/j.issn.1000-7377.2024.09.016
文献标志码:
A
摘要:
目的:探讨乳腺癌改良根治术患者近端肋间臂神经阻滞联合前锯肌平面阻滞(SAPB)的临床效果。方法:选择在全身麻醉下行乳腺癌改良根治术的患者60例,采用随机数字表法分为近端肋间臂神经阻滞联合SAPB组(联合组)和SAPB组(前锯肌组),每组30例。两组分别在全麻诱导后行超声引导下近端肋间臂神经阻滞联合前锯肌平面阻滞和前锯肌平面阻滞。采用视觉模拟评分法(VAS)记录患者术后30 min及2、4、8、24 h疼痛情况。记录术中瑞芬太尼使用总量、术后24 h舒芬太尼使用总量、补救镇痛时间、24 h内补救镇痛率以及不良反应情况。结果:与前锯肌组比较,联合组术后2、8 h的VAS评分降低,术中瑞芬太尼的使用量及术后舒芬太尼的使用量减少,总不良反应率降低,首次补救镇痛时间延长,24 h内补救镇痛率降低(均P<0.05)。结论:与前锯肌平面阻滞相比,近端肋间臂神经阻滞联合前锯肌平面阻滞可以减少围手术期阿片类药物使用,改善乳腺癌改良根治术患者术后镇痛效果。
Abstract:
Objective:To investigate the clinical effect of proximal intercostobrachial nerve block combined with serratus anterior plane block(SAPB)in patients undergoing modified radical mastectomy for breast cancer.Methods:Sixty patients undergoing modified radical mastectomy for breast cancer under general anesthesia were randomly divided into proximal intercostulobrachial nerve block combined with SAPB group(combined group)and SAPB group(serratus anterior group),with 30 patients in each group.After induction of general anesthesia,the two groups underwent ultrasound-guided proximal intercostabrachial nerve block combined with serratus anterior plane block and serratus anterior plane block,respectively.VAS was used to record the pain at 30 min,2,4,8 and 24 hours after operation.The total amount of remifentanil used during operation,the total amount of sufentanil used within 24 hours after operation,the time of rescue analgesia,the rate of rescue analgesia within 24 hours,and adverse reactions were recorded.Results:Compared with the serratus anterior group,the VAS scores at 2,8 hours after operation were significantly decreased,the consumption of intraoperative remifentanil and postoperative sufentanil were decreased,the total adverse reaction rate was decreased,the first rescue analgesia time was prolonged,and the rescue analgesia rate within 24 hours was decreased in the combined group(all P<0.05).Conclusion:Compared with serratus anterior plane block,proximal intercostaobrachial nerve block combined with serratus anterior plane block can reduce perioperative opioid use and improve postoperative analgesia in patients undergoing modified radical mastectomy for breast cancer.

参考文献/References:

[1] SUNG H,FERLAY J,SIEGEL R L,et al.Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2021,71(3):209-249.
[2] 郑荣寿,张思维,孙可欣,等.2016年中国恶性肿瘤流行情况分析[J].中华肿瘤杂志,2023,45(3):212-220.
[3] 熊洁,段志财,左怀全.中美乳腺癌流行病学特征对比及防控策略分析[J].中国普外基础与临床杂志,2024,31(1):50-55.
[4] 李东生,孙思敬,路忠志,等.乳腺癌手术方式选择及随访分析[J].国际外科学杂志,2020,47(9):627-631.
[5] BAKR M A,MOHAMED S A,MOHAMAD M F,et al.Effect of dexmedetomidine added to modified pectoral block on postoperative pain and stress response in patient undergoing modified radical mastectomy[J].Pain Physician,2018,21(2):e87-e96.
[6] HABIB A S,KERTAI M D,COOTER M,et al.Risk factors for severe acute pain and persistent pain after surgery for breast cancer:A prospective observational study[J].Reg Anesth Pain Med,2019,44(2):192-199.
[7] 刘馨,冷玉芳,张梦婕.乳腺癌术后疼痛的临床研究进展[J].国际麻醉学与复苏杂志,2021,42(11):1217-1220.
[8] WANG L,COHEN J C,DEVASENAPATHY N,et al.Prevalence and intensity of persistent post-surgical pain following breast cancer surgery:A systematic review and meta-analysis of observational studies[J].Br J Anaesth,2020,125:346-357.
[9] XIE C,RAN G,CHEN D,et al.A narrative review of ultrasound-guided serratus anterior plane block[J].Ann Palliat Med,2021,10(1):700-706.
[10] SAMERCHUA A,LEURCHARUSMEE P,PANJASAWATWONG K,et al.Cadaveric study identifying clinical sonoanatomy for proximal and distal approaches of ultrasound-guided intercostobrachial nerve block[J].Reg Anesth Pain Med,2020,45(11):853-859.
[11] 谢晓亮,BISSOMBOLO M R,樊天佑,等.电针华佗夹脊穴与椎间孔镜治疗腰椎间盘突出症对比研究[J].陕西中医,2022,43(6):789-792.
[12] 李文高,李强,贾承明,等.补髓活血健骨汤联合微创保髋术治疗早期非创伤性股骨头缺血性坏死疗效研究[J].陕西中医,2023,44(7):929-932.
[13] 徐向宇,贾薇,蒋朝阳.多模式镇痛在胃肠道术后患者中的应用[J].中国当代医药,2023,30(11):38-41.
[14] ALBRECHT E,REYNVOET M,FOURNIER N,et al.Dose-response relationship of perineural dexamethasone for interscalene brachial plexus block:A randomised,controlled,triple-blind trial[J].Anaesthesia,2019,74(8):1001-1008.
[15] 蒋敢,王军,王会东.舒芬太尼联合罗哌卡因肋间神经阻滞对乳腺癌患者术后镇痛、免疫功能及应激反应的影响[J].陕西医学杂志,2019,48(8):1077-1079,1084.
[16] 郭欣欣,史丽娜,李哲,等.连续前锯肌阻滞对老年患者术后肺功能、镇痛及免疫功能的影响研究[J].陕西医学杂志,2019,48(12):1601-1604.
[17] MANIKER R B,JOHNSON R L,TRAN D Q.Interfacial plane blocks for breast surgery:Which surgery to block,and which block to choose?[J].Anesth Analg,2020,130(6):1556-1558.
[18] BISWAS A,CASTANOV V,LI Z,et al.Serratus plane block:A cadaveric study to evaluate optimal injectate spread[J].Reg Anesth Pain Med,2018,43(8):854-858.
[19] SHI K,CHEN Y,LIU L,et al.Comparison of the effect of different volumes ropivacaine on deep serratus anterior plane block in patients undergoing breast surgery:A prospective randomized double-blinded trial[J].Ann Palliat Med,2021,10(6):6104-6111.
[20] BHOI D,JAIN D,CHHABRA A,et al.Analgesic efficacy of superficial versus deep serratus plane block for modified radical mastectomy under general anaesthesia:A randomised comparative study[J].Indian J Anaesth,2022,66:s307-s313.
[21] HU N Q,HE Q Q,QIAN L,et al.Efficacy of ultrasound-guided serratus anterior plane block for postoperative analgesia in patients undergoing breast surgery:A systematic review and meta-analysis of randomised controlled trials[J].Pain Res Manag,2021,2021:7849623.
[22] 陈默曦,陈勇柱,徐成,等.超声引导下肋间臂神经阻滞的研究进展[J].临床麻醉学杂志,2022,38(5):540-543.
[23] 苏小君,杨英,方燕梅,等.乳腺癌术后疼痛综合征的临床特征及危险因素分析[J].局解手术学杂志,2021,30(12):1057-1060.
[24] 黄艳芳,雷银富,李世珍,等.乳腺癌术后疼痛综合征发生情况及影响因素分析[J].西南医科大学学报,2019,42(3):280-283.
[25] 杨坤,王玉苗.超声引导下肋间臂神经阻滞治疗乳房切除术后疼痛综合征的临床效果[J].临床医药文献电子杂志,2018,5(73):47-48.
[26] KHAN J S,LADHA K S,ABDALLAH F,et al.Treating persistent pain after breast cancer surgery[J].Drugs,2020,80(1):23-31.

备注/Memo

备注/Memo:
基金项目:陕西省科技计划项目(2021JQ-918)
更新日期/Last Update: 2024-09-04