[1]周 毅,张元炜,李 剑,等.胰腺脂肪浸润CT表现与冠状动脉硬化狭窄程度相关性分析[J].陕西医学杂志,2024,(9):1202-1205.[doi:DOI:10.3969/j.issn.1000-7377.2024.09.010]
 ZHOU Yi,ZHANG Yuanwei,LI Jian,et al.Correlation between CT findings of pancreatic fatty infiltration and degree of coronary artery stenosis[J].,2024,(9):1202-1205.[doi:DOI:10.3969/j.issn.1000-7377.2024.09.010]
点击复制

胰腺脂肪浸润CT表现与冠状动脉硬化狭窄程度相关性分析
分享到:

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2024年9期
页码:
1202-1205
栏目:
临床研究
出版日期:
2024-09-05

文章信息/Info

Title:
Correlation between CT findings of pancreatic fatty infiltration and degree of coronary artery stenosis
作者:
周 毅1张元炜1李 剑2代 坤3
(1.陕西省中医医院放射科,陕西 西安 710003; 2.西安凤城医院放射科,陕西 西安 710016; 3.西安市阎良铁路医院检验科,陕西 西安 710089)
Author(s):
ZHOU YiZHANG YuanweiLI JianDAI Kun
(Department of Radiology,Shaanxi Provincial Hospital of Chinese Medicine,Xi'an 710003,China)
关键词:
胰腺脂肪浸润 冠状动脉粥样硬化 计算机断层扫描 独立危险因素 相关性
Keywords:
Pancreatic fatty infiltration Coronary artery stenosis Computed tomography Independent risk factors Correlation
分类号:
R 589.2
DOI:
DOI:10.3969/j.issn.1000-7377.2024.09.010
文献标志码:
A
摘要:
目的:探究胰腺脂肪浸润(PFI)CT表现与冠状动脉粥样硬化狭窄严重程度的相关性。方法:回顾性收集住院患者212例,行上腹部CT扫描后,将90例诊断为PFI的患者纳入试验组,另外122例非PFI患者纳入对照组。通过冠状动脉CT血管造影(CTA)诊断冠状动脉狭窄的严重程度,在腹部平扫CT图像上观察胰腺形态并测量CT值。比较两组患者一般资料及胰腺、脾、肝CT值,总体及不同性别患者冠脉狭窄程度,分析冠脉狭窄的危险因素及胰腺CT值与冠脉狭窄相关性。结果:试验组患者年龄和空腹血糖高于对照组,胰腺CT值低于对照组(均P<0.05)。试验组冠脉狭窄程度高于对照组(P<0.05)。试验组男性冠脉狭窄率高于女性(P<0.05)。试验组男性患者冠脉狭窄程度高于对照组。年龄是对照组的独立危险因素,胰腺CT值是试验组的独立危险因素(均P<0.05)。试验组中胰腺CT值与冠脉狭窄程度呈负相关(r=-0.538,P<0.05)。结论:PFI患者胰腺CT值与冠脉狭窄呈负相关,有助于预测冠状动脉狭窄的发生风险。
Abstract:
Objective:To investigate the correlation between CT findings of pancreatic fatty infiltration(PFI)and the severity of coronary artery stenosis.Methods:A total of 212 hospitalized patients were retrospectively collected.After upper abdominal CT scan,90 patients diagnosed with PFI were included in the experimental group,and 122 patients without PFI were included in the control group.The severity of coronary artery stenosis was diagnosed by coronary artery CT angiography(CTA).The morphology of pancreas was observed and the CT value was measured on abdominal plain CT images.The general data and CT values of pancreas,spleen and liver were compared between the two groups,and the degree of coronary artery stenosis in the whole group and different genders were compared.The risk factors of coronary artery stenosis and the correlation between pancreatic CT value and coronary artery stenosis were analyzed.Results:The age and fasting blood glucose of the experimental group were higher than those of the control group,and the CT value of the pancreas was lower than that of the control group(all P<0.05).The degree of coronary artery stenosis in the experimental group was higher than that in the control group(P<0.05).The rate of coronary artery stenosis was higher in men than that in woemn in the experimental group(P<0.05).The degree of coronary artery stenosis was higher in male patients in the experimental group than in the control group.Age was an independent risk factor for the control group,and pancreatic CT value was an independent risk factor for the experimental group(both P<0.05).The CT value of pancreas was negatively correlated with the degree of coronary artery stenosis in the experimental group(r=-0.538,P<0.05).Conclusion:CT value of pancreas is negatively correlated with coronary artery stenosis in patients with PFI,which can help to predict the risk of coronary artery stenosis.

参考文献/References:

[1] 杜茂宗,姚海木.严重冠脉狭窄合并2型糖尿病患者侧支循环形成的影响因素[J].河南医学研究,2020,29(6):984-987.
[2] MOHAMAD N,IKHSAN N D,ISMAIL R A R,et al.The effect of health education program on knowledge of coronary heart disease(CHD)among public in puncak alam,selangor[J].Advanced Science Letters,2018,24(1):556-558.
[3] 耿倩雯,胡健强,张东伟,等.凝血酶原时间、活化部分凝血活酶时间、纤维蛋白原、凝血酶时间、心肌指标检测在冠心病诊断中的意义[J].陕西医学杂志,2022,51(10):1309-1312.
[4] 杜艳梅,田展松,李红,等.ApoE 基因多态性、Hcy与2型糖尿病患者发生冠状动脉粥样硬化性心脏病的相关性研究[J].空军军医大学学报,2023,44(8):717-720.
[5] 胡盛寿,高润霖,刘力生,等.《中国心血管病报告2018》概要[J].中国循环杂志,2019,34(3):209-220.
[6] HEBER S D,HETTERICH H,LORBEER R,et al.Pancreatic fat content by magnetic resonance imaging in subjects with prediabetes,diabetes,and controls from a general population without cardiovascular disease[J].PLoS One,2017,12(5):e177154.
[7] 时之秀,杜训松,曹洁.老年冠心病患者 PCI 术后主要心脑血管不良事件发生情况及影响因素分[J].临床心血管病杂志,2022,38(2):132-136.
[8] 张洪明,宇克莉,魏榆,等.羌族成人肥胖指标与内脏脂肪等级的关系[J].天津师范大学学报(自然科学版),2018,38(4):73-76.
[9] 赖敬波,李晓苗,赵国宏,等.肥胖人群下肢肌肉含量及其与内脏脂肪型肥胖关系研究[J].陕西医学杂志,2020,49(12):1566-1568,1572.
[10] VAN-GEENEN E J,SMITS M M,SCHREUDER T C,et al.Nonalcoholic fatty liver disease is related to nonalcoholic fatty pancreas disease[J].Pancreas,2010,39(8):1185-1190.
[11] 陆雨纯,应长江,沃眉宏,等.胰腺脂肪浸润的CT参数与2型糖尿病合并脑梗死的相关性研究[J].医学研究杂志,2023,52(7):66-70.
[12] TEMPLE N J.Fat,sugar,whole grains and heart disease:50 years of confusion[J].Nutrients,2018,10(1):39.
[13] 周世敏,曹雷,孙悦,等.外周血载脂蛋白A1、载脂蛋白B、脂蛋白(a)在颈动脉粥样硬化斑块易损性评价中的价值研究[J].陕西医学杂志,2023,52(11):1541-1545.
[14] KAESS B M,PEDLEY A,MASSARO J M,et al.The ratio of visceral to subcutaneous fat,a metric of body fat distribution,is a unique correlate of cardiometabolic risk[J].Diabetologia,2012,55(10):2622-2630.
[15] BRITTON K A,MASSARO J M,MURABITO J M,et al.Body fat distribution,incident cardiovascular disease,cancer,and all-cause mortality[J].J Am Coll Cardiol,2013,62:921-925.
[16] 冯金艳,邱丽华.MRI检查对颈动脉粥样硬化斑块的诊断价值研究[J].陕西医学杂志,2019,48(4):467-469.
[17] SATIZABAL C L,SAMIERI C,DAVIS-PLOURDE K L,et al.APOE and the association of fatty acids with the risk of stroke,coronary heart disease,and mortality[J].Stroke,2018,49(12):2822-2829.
[18] 凌杰兵,马斌.血清超敏C-反应蛋白与前白蛋白比值对急性心肌梗死患者并发心力衰竭的预测价值研究[J].临床误诊误治,2018,31(1):82-85.
[19] 刘子歌,刘洋,宋国瑞,等.泡沫细胞在动脉粥样硬化形成过程中的作用研究进展[J].陕西医学杂志,2020,49(10):1363-1366.
[20] 马杰,李晓阳,邢国凤,等.胰腺脂肪浸润与胰岛素抵抗关系的临床与CT分析[J].实用临床医药杂志,2012,16(17):161-163.
[21] 杨亚锋,王萍,王利,等.2型糖尿病合并腹型肥胖男性患者胰岛素抵抗与内脏脂肪面积相关性研究[J].陕西医学杂志,2020,49(6):717-719.
[22] 王楚莹,马师洋,赵平,等.胰腺脂肪浸润与胰腺癌的相关性分析[J].现代肿瘤医学,2023,31(9):1686-1690.
[23] 张钦和,刘爱连.胰腺脂肪定量的CT和MRI研究进展[J].国际医学放射学杂志,2018,41(2):185-189.
[24] 孙朋涛,都雪朝,王若顿,等.胰腺脂肪浸润对2型糖尿病患者冠状动脉粥样硬化严重程度的预测价值[J].中国医学科学院学报,2020,42(2):172-177.
[25] 许顶立.糖尿病合并冠心病患者的临床特点及治疗策略[J].中华医学信息导报,2015,30(6):20.
[26] 崔新月,靳之,韩东建,等.糖尿病对低密度脂蛋白胆固醇达标的冠心病患者支架内再狭窄的影响[J].郑州大学学报(医学版),2020,55(3):297-301.
[27] 韩冬,贺太平,于楠,等.中重度非酒精性脂肪肝与冠心病的相关性[J].中国医学影像学杂志,2020,28(12):942-946.

备注/Memo

备注/Memo:
基金项目:陕西省卫生健康科研基金资助项目(2022B012)
更新日期/Last Update: 2024-09-04