[1]罗江淼,如斯坦木,阿特尔,等.骨关节炎发病机制及治疗研究进展[J].陕西医学杂志,2024,(7):1006-封3.[doi:DOI:10.3969/j.issn.1000-7377.2024.07.032]
 LUO Jiangmiao,Rustam A,A Teer,et al.Progress of pathogenesis and treatment progress of osteoarthritis[J].,2024,(7):1006-封3.[doi:DOI:10.3969/j.issn.1000-7377.2024.07.032]
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骨关节炎发病机制及治疗研究进展
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2024年7期
页码:
1006-封3
栏目:
综 述
出版日期:
2024-07-05

文章信息/Info

Title:
Progress of pathogenesis and treatment progress of osteoarthritis
作者:
罗江淼1如斯坦木1阿特尔1王维山2
(1.石河子大学,新疆 石河子 832000; 2.石河子大学第一附属医院,新疆 石河子 832008)
Author(s):
LUO JiangmiaoRustam AA TeerWANG Weishan
(Shihezi University,Shihezi 832000,China)
关键词:
膝骨性关节炎 发病机制 诊断 治疗方法 中医
Keywords:
Knee osteoarthritis Pathogenesis Diagnosis Treatment method Traditional Chinese medicine
分类号:
R 684.3
DOI:
DOI:10.3969/j.issn.1000-7377.2024.07.032
文献标志码:
A
摘要:
骨性关节炎(OA)是一种以关节逐渐退变为主要特征的慢性骨性关节疾病,患者症状上多表现为关节疼痛或畸形。临床上最常见的 OA 为膝骨性关节炎(KOA)。KOA 患病率日益升高且中老年人居多,其发病机制尚未完全明确,但越来越多的研究表明多种蛋白酶在微观层面上起着重要作用。由于该疾病导致的关节疼痛与功能障碍,会严重影响着人民健康及生活质量,给患者家庭与社会带来了多重负担,由此可见对 KOA 治疗方法进行研究显得尤为重要。逐年增加的临床治疗结果表明手术治疗、中医治疗与机器人辅助治疗均可带来良好的治疗效果。现就通过概述 KOA 患者发病机制、诊治进展,旨在为KOA的临床治疗工作提供参考,为患者的生活质量提供保障。
Abstract:
Osteoarthritis(OA)is a chronic bony joint disease characterized by gradual degeneration of the joints,which is often characterized by joint pain or deformity.The most common form of OA is knee osteoarthritis(KOA),which is increasing in prevalence and is predominantly seen in middle-aged and elderly people.The pathogenesis of KOA has not yet been fully defined,but an increasing number of studies have shown that various proteases play an important role at the microscopic level.The joint pain and dysfunction caused by this disease have a serious impact on people's health and quality of life,and bring multiple burdens to the patients' families and society,which makes research on the treatment of KOA particularly important.Clinical results,which are increasing year by year,show that surgical treatment,traditional Chinese medicine treatment,and robot-assisted treatment can all bring good therapeutic effects.Now,we summarize the pathogenesis,diagnosis and treatment progress of KOA patients,aiming to provide reference for the clinical treatment of KOA and guarantee the quality of life of patients.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(82160423)
更新日期/Last Update: 2024-07-04