[1]朱钦辉,陈丹霞,魏统国.替罗非班联合直接取栓对急诊急性脑梗死患者血管再通率影响的临床研究[J].陕西医学杂志,2024,(1):95-98,103.[doi:DOI:10.3969/j.issn.1000-7377.2024.01.021]
　ZHU Qinhui,CHEN Danxia,WEI Tongguo.Effect of direct thrombectomy combined with tirofiban on rate of vascular revascularization in emergency patients with acute cerebral infarction[J].,2024,(1):95-98,103.[doi:DOI:10.3969/j.issn.1000-7377.2024.01.021]
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替罗非班联合直接取栓对急诊急性脑梗死患者血管再通率影响的临床研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2024年1期
页码:
95-98,103
栏目:
药物与临床
出版日期:
2024-01-31

文章信息/Info

Title:
Effect of direct thrombectomy combined with tirofiban on rate of vascular revascularization in emergency patients with acute cerebral infarction
作者:
朱钦辉; 陈丹霞; 魏统国
(梅州市人民医院神经内科,广州 梅州 514000)
Author(s):
ZHU Qinhui; CHEN Danxia; WEI Tongguo
(Department of Neurology,Meizhou People's Hospital,Meizhou 514000,China)
关键词:
急性脑梗死;  直接取栓;  替罗非班;  急诊;  穿刺成功到再通时间;  神经功能
Keywords:
Acute cerebral infarction;  Direct thrombectomy;  Tirofiban;  Emergency;  Time from successful puncture to recanalization;  Neural function
分类号:
R 743.3
DOI:
DOI:10.3969/j.issn.1000-7377.2024.01.021
文献标志码:
A
摘要:
目的:本研究旨在探讨直接取栓联合替罗非班对急诊急性脑梗死患者血管再通率的影响。方法:以收治的103例急诊急性脑梗死为研究对象,采用随机数字表法将其分为对照组(给予直接取栓治疗,51例)和研究组(给予直接取栓联合替罗非班治疗,52例)。统计两组患者穿刺成功到再通时间、住院时间及并发症发生情况,对比两组神经功能、再通血流分级及mRS评分。结果:研究组穿刺成功到再通时间及住院时间均少于对照组(均P<0.05)。治疗后,研究组神经功能评分低于对照组(P<0.05),研究组再通血流分级中的3级高于对照组(P<0.05),研究组再通血流率为94.23%(49/52),对照组再通血流率为75.00%(39/52),研究组再通血流率高于对照组(P<0.05)。治疗后,研究组mRS评分低于对照组(P<0.05),研究组并发症发生率低于对照组(P<0.05)。结论: 直接取栓联合替罗非班能够有效提高急诊急性脑梗死患者血管再通率,改善患者预后水平。
Abstract:
Objective:To investigate the effect of direct thrombectomy combined with tirofiban on the rate of vascular revascularization in patients with emergency acute cerebral infarction.Methods:A total of 103 cases of acute cerebral infarction were randomly divided into control group(treated with direct thrombectomy,51 cases)and study group(treated with direct thrombectomy combined with tirofiban,52 cases).The time from successful puncture to recanalization,hospitalization time and complications were recorded.The neurological function,recanalization blood flow grade and mRS score were compared between the two groups.Results:The time from successful puncture to recanalization and hospitalization time in the study group were lower than those in the control group(all P<0.05).After treatment,the neurological function score of the study group was lower than that of the control group(P<0.05).Grade 3 of recanalization blood flow in the study group was higher than that in the control group(P<0.05).The recanalization blood flow rate was 94.23%(49/52)in the study group and 75.00%(39/52)in the control group.The recanalization blood flow rate in study group was higher than that in control group(P<0.05).After treatment,the mRS score of the study group was lower than that of the control group(P<0.05).The complication rate of the study group was lower than that of the control group(P<0.05).Conclusion:Direct thrombectomy combined with tirofiban can effectively improve vascular revascularization rate and improve the prognosis of patients with emergency acute cerebral infarction.

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备注/Memo

备注/Memo:
基金项目:广东省中医药局科研项目(20222235)
更新日期/Last Update: 2024-01-05