[1]李 民,曹 杰,刘晓斌,等.老年高血压脑出血并发卒中相关性肺炎早期患者血清感染指标的检测及临床意义[J].陕西医学杂志,2023,52(10):1419-1422.[doi:DOI:10.3969/j.issn.1000-7377.2023.10.031]
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老年高血压脑出血并发卒中相关性肺炎早期患者血清感染指标的检测及临床意义
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
52
期数:
2023年10期
页码:
1419-1422
栏目:
临床检验
出版日期:
2023-10-05

文章信息/Info

作者:
李 民曹 杰刘晓斌孟发财李 帅张 杰
(陕西省人民医院神经外科,陕西 西安 710068)
关键词:
脑出血 卒中相关性肺炎 白介素-6 C-反应蛋白 淀粉样蛋白A 降钙素原
分类号:
R 743.34
DOI:
DOI:10.3969/j.issn.1000-7377.2023.10.031
文献标志码:
A
摘要:
目的: 探究老年高血压脑出血患者在合并卒中相关性肺炎(SAP)早期时,体内白细胞介素-6(IL-6)、C反应蛋白(CRP)、血清淀粉样蛋白A(SAA)及降钙素原(PCT)水平的动态变化及其临床意义。方法:选取老年高血压脑出血病患者90例,其中SAP感染组45例,未感染对照组45例。通过比较两组患者血清白介素-6(IL-6)、C-反应蛋白(CRP)、淀粉样蛋白A(SAA)及降钙素原(PCT)水平差异,分析血清感染指标单独检测以及联合检测对老年患者SAP早期诊断的敏感性和特异性。结果:SAP组血清感染指标水平显著高于对照组(P<0.05),SAP组血清SAA、PCT与IL-6、CRP呈正相关(均P<0.05),血清IL-6、CRP、SAA及PCT对老年患者SAP的早期诊断,曲线下面积分别为0.742、0.684、0.854、0.835,敏感度分别为68.9%、71.1%、73.3%、84.4%,特异度分别为77.8%、62.2%、86.7%、77.8%; 血清IL-6、CRP、SAA及PCT联合检测对患者SAP的诊断,曲线下面积分别为0.925,敏感度为95.6%,特异度为75.6%。结论: 血清IL-6、CRP、SAA及PCT水平对老年高血压脑出血患者合并SAP的诊断有临床意义,并且感染指标联合检测诊断更有意义。

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备注/Memo

备注/Memo:
基金项目:陕西省重点研发计划项目(2021SF-355)
更新日期/Last Update: 2023-10-07