[1]赵 志,林进权,王春雨,等.铁死亡、自噬及两者关联在胃癌发生中的研究进展[J].陕西医学杂志,2023,52(9):1268-1271.[doi:DOI:10.3969/j.issn.1000-7377.2023.09.036]
 ZHAO Zhi,LIN Jinquan,WANG Chunyu,et al.Research progress on ferroptosis,autophagy and their correlation in gastric cancer[J].,2023,52(9):1268-1271.[doi:DOI:10.3969/j.issn.1000-7377.2023.09.036]
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铁死亡、自噬及两者关联在胃癌发生中的研究进展
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
52
期数:
2023年9期
页码:
1268-1271
栏目:
综 述
出版日期:
2023-09-05

文章信息/Info

Title:
Research progress on ferroptosis,autophagy and their correlation in gastric cancer
作者:
赵 志12林进权12王春雨1冉 潇12
(1.桂林医学院,广西 桂林 541100; 2.桂林市人民医院胃肠外科,广西 桂林 541000)
Author(s):
ZHAO ZhiLIN JinquanWANG ChunyuRAN Xiao
(Guilin Medical University,Guilin 541100,China)
关键词:
胃癌 铁死亡 自噬 自噬依赖性铁死亡 铁蛋白自噬 钟表性自噬
Keywords:
Gastric Cancer Ferroptosis Autophagy Autophagy-dependent ferroptosis Ferritinophagy Clockophagy
分类号:
R 735.2
DOI:
DOI:10.3969/j.issn.1000-7377.2023.09.036
文献标志码:
A
摘要:
铁死亡及自噬作为两种不同的细胞死亡形式,对胃癌的发生具有重要影响。自噬是一种以维持内环境稳态为目的而演变的保守的降解途径,而铁死亡是一种新型的细胞调控性死亡。自噬和铁死亡与胃癌的发生、发展具有密切的关系。现对铁死亡、自噬及两者关联在胃癌中的研究进展进行阐述,以为胃癌的诊治提供新思路。
Abstract:
Ferroptosis and autophagy as two different forms of cell death have important effects on the occurrence of gastric cancer.Autophagy is a conservative degradation pathway evolved for the purpose of maintaining homeostasis of the internal environment,while ferroptosis is a new type of cell regulatory death.Autophagy is closely related to ferroptosis and the occurrence and development of gastric cancer.This article reviews the research progress of ferroptosis,autophagy and their correlation in gastric cancer,in order to provide new ideas for the diagnosis and treatment of gastric cancer.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(82060561); 广西壮族自治区自然科学基金资助项目(2018GXNSFBA050047); 广西壮族自治区研究生教育创新计划项目(YCSW2022379)
更新日期/Last Update: 2023-09-04