[1]洪海燕,刘宇杰,方丽妮,等.超声检查子宫动脉、脐动脉血流参数对胎儿生长受限的诊断价值及临床监测意义[J].陕西医学杂志,2023,52(5):567-570.[doi:DOI:10.3969/j.issn.1000-7377.2023.05.016]
　HONG Haiyan,LIU Yujie,FANG Lini,et al.Diagnostic value and clinical monitoring significance of blood flow parameters of uterine artery and umbilical artery examined by abdominal ultrasound in fetal growth restriction[J].,2023,52(5):567-570.[doi:DOI:10.3969/j.issn.1000-7377.2023.05.016]
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超声检查子宫动脉、脐动脉血流参数对胎儿生长受限的诊断价值及临床监测意义
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
52
期数:
2023年5期
页码:
567-570
栏目:
临床研究
出版日期:
2023-05-05

文章信息/Info

Title:
Diagnostic value and clinical monitoring significance of blood flow parameters of uterine artery and umbilical artery examined by abdominal ultrasound in fetal growth restriction
作者:
洪海燕1; 刘宇杰1; 方丽妮1; 樊健敏2
(1.三亚中心医院 海南省第三人民医院功能科,海南 三亚 572000; 2.陕西省中医医院,陕西 西安 710003)
Author(s):
HONG Haiyan; LIU Yujie; FANG Lini; FAN Jianmin
(Department of Function,Sanya Central Hospital,Sanya 572000,China)
关键词:
胎儿生长受限;  腹部超声;  子宫动脉;  脐动脉;  血流参数;  诊断价值
Keywords:
Fetal growth restriction;  Abdominal ultrasound;  Uterine artery;  Umbilical artery;  Blood flow parameters;  Diagnostic value
分类号:
R 714.51
DOI:
DOI:10.3969/j.issn.1000-7377.2023.05.016
文献标志码:
A
摘要:
目的:探讨腹部超声检查子宫动脉和脐动脉血流参数对胎儿生长受限的诊断价值及临床监测意义。方法: 选取96例孕妇作为研究对象,根据产前检查结果分为胎儿生长受限组(28例)和正常妊娠组(68例)。两组均给予腹部超声检查。比较两组子宫动脉血流参数,两组脐动脉血流参数,并采用受试者工作特征(ROC)曲线分析子宫动脉和脐动脉血流参数对胎儿生长受限的诊断价值,统计两组妊娠结局。结果:胎儿生长受限组子宫动脉的阻力指数(RI)、搏动指数(PI)及收缩期峰值流速/舒张末期流速比值(S/D)均高于正常妊娠组(均P<0.05)。胎儿生长受限组脐动脉的RI、PI及S/D均高于正常妊娠组(均P<0.05)。ROC曲线分析结果显示,子宫动脉、脐动脉及联合检测血流参数对预测胎儿生长受限的敏感度分别为68.00%、88.00%、91.67%,特异度分别为78.18%、80.00%、94.55%,其中联合诊断的诊断价值最高,差异有统计学意义(均P<0.05)。胎儿生长受限组早产、急诊剖宫产、转入新生儿重症监护病房(NICU)及新生儿1 min 阿氏评分(Apgar)<7分占比分别为39.29%、46.43%、27.28%、32.14%,均高于正常妊娠组的5.88%、5.88%、5.88%、2.94%; 新生儿出生体质量及羊水指数均低于正常妊娠组(P<0.05)。结论:胎儿生长受限出现围产儿不良结局的风险较高,子宫动脉、脐动脉的RI、PI及S/D异常与胎儿生长受限密切相关,临床可据此对胎儿生长受限进行诊断,以降低不良结局的风险,其中子宫动脉及脐动脉血流参数联合检测具有较高的诊断价值。
Abstract:
Objective:To investigate the diagnostic value and clinical monitoring significance of blood flow parameters of uterine artery and umbilical artery examined by abdominal ultrasound in fetal growth restriction.Methods:A total of 96 pregnant women were selected as the study subjects.According to the prenatal examination results,they were divided into the fetal growth restriction group(28 cases)and the normal pregnancy group(68 cases).Abdominal ultrasonography was performed in both groups.The uterine artery blood flow parameters and umbilical artery blood flow parameters of the two groups were compared.The diagnostic value of uterine artery and umbilical artery blood flow parameters for fetal growth restriction was analyzed by using the receiver operating characteristic(ROC)curve.The pregnancy outcomes of the two groups were counted.Results:The Resistance Index(RI),Pulsatility Index(PI)and the ratio of peak systolic flow rate to end diastolic flow rate(S/D)of uterine artery in the fetal growth restriction group were higher than those in the normal pregnancy group(all P<0.05).RI,PI and S/D of umbilical artery in the fetal growth restriction group were higher than those in the normal pregnancy group(all P<0.05).The ROC curve analysis results showed that the sensitivity of uterine artery,umbilical artery and joint detection of blood flow parameters to predict fetal growth restriction was 68.00%,88.00% and 91.67% respectively,and the specificity was 78.18%,80.00% and 94.55% respectively.The diagnostic value of joint detection was the highest,with statistical significance(all P<0.05).The proportion of premature delivery,emergency cesarean section,transfer to neonatal intensive care unit(NICU)and score of newborn Apgar score <7 in the fetal growth restriction group were 39.29%,46.43%,27.28% and 32.14% respectively,which were higher than 5.88%,5.88%,5.88% and 2.94% in the normal pregnancy group,and the birth weight and amniotic fluid index of neonates were lower than those of the normal pregnancy group(all P<0.05).Conclusion:Fetal growth restriction had a higher risk of perinatal adverse outcome.Abnormal RI,PI and S/D of uterine artery and umbilical artery were closely related to fetal growth restriction.Clinical diagnosis of fetal growth restriction can be made based on this to reduce the risk of adverse outcome.Among them,the combined detection of blood flow parameters of uterine artery and umbilical artery had a higher diagnostic value.

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相似文献/References:

[1]宫 婷,潘艳艳.孕11～13+6周子宫动脉频谱与不明原因胎儿宫内生长受限相关性研究[J].陕西医学杂志,2019,(8):1049.
　GONG Ting,PAN Yanyan..Retrospective study on correlation between uterine artery doppler spectrum and IUGR with unknown causes in pregnant women of 11～13+6  gestational weeks[J].,2019,(5):1049.
[2]秦凤娟,张福娥,王小凤,等.胎儿生长受限患者血清Klotho蛋白、ADMA表达及临床意义[J].陕西医学杂志,2022,51(4):488.[doi:DOI:10.3969/j.issn.1000-7377.2022.04.025]
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备注/Memo

备注/Memo:
基金项目:国家卫生健康委员会“十四五”规划全国重点课题(YYWS4148)
更新日期/Last Update: 2023-05-05