[1]张 娅,张 洁.心肌胰岛素抵抗致心力衰竭研究进展[J].陕西医学杂志,2023,52(4):495-封3.[doi:DOI:10.3969/j.issn.1000-7377.2023.04.030]
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心肌胰岛素抵抗致心力衰竭研究进展
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
52
期数:
2023年4期
页码:
495-封3
栏目:
综 述
出版日期:
2023-04-05

文章信息/Info

作者:
张 娅1张 洁2
(1.陕西中医药大学第一临床医学院,陕西 咸阳 712046; 2.西安市第五医院,陕西 西安 710082)
关键词:
心力衰竭 心肌胰岛素抵抗 氧化应激 内质网应激 钙稳态 线粒体功能障碍
分类号:
R 541
DOI:
DOI:10.3969/j.issn.1000-7377.2023.04.030
文献标志码:
A
摘要:
心力衰竭(HF)是我国及全世界主要公共卫生问题,由于其发病率和患病率显著上升,给社会和家庭造成巨大经济负担。胰岛素抵抗(IR)是机体对胰岛素刺激反应性降低,同时是心衰、冠心病等心血管病的独立危险因素。因胰岛素抵抗导致心肌细胞结构和功能改变而引发心衰,是研究心衰的重要途径之一。现通过心肌胰岛素抵抗机制进展相关性研究,概述心肌胰岛素抵抗所致的心衰机制的发生进展,以期为心衰后续的诊疗提供新的思路。

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备注/Memo

备注/Memo:
基金项目:陕西省科技厅科研项目(2019SF-177); 西安市创新能力强基计划项目(21YXYJ0049)
更新日期/Last Update: 2023-04-06