[1]左莉莉,邓笑伟.40岁及以上体检人群肺功能和动脉硬化相关性研究[J].陕西医学杂志,2023,52(1):40-44.[doi:DOI:10.3969/j.issn.1000-7377.2023.01.009]
　ZUO Lili,DENG Xiaowei.Correlation between pulmonary function and arteriosclerosis in health examination population over 40 years[J].,2023,52(1):40-44.[doi:DOI:10.3969/j.issn.1000-7377.2023.01.009]
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40岁及以上体检人群肺功能和动脉硬化相关性研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
52
期数:
2023年1期
页码:
40-44
栏目:
临床研究
出版日期:
2023-01-05

文章信息/Info

Title:
Correlation between pulmonary function and arteriosclerosis in health examination population over 40 years
作者:
左莉莉1; 2; 邓笑伟1; 3
(1.锦州医科大学,辽宁 锦州 121001; 2.衡水市人民医院健康管理中心,河北 衡水 053000; 3.解放军总医院第三医学中心,北京 100039)
Author(s):
ZUO Lili; DENG Xiaowei
(Jinzhou Medical University,Jinzhou 121001,China)
关键词:
动脉硬化;  颈动脉内膜中膜厚度;  踝肱指数;  肺功能;  相关性;  体检
Keywords:
Arteriosclerosis;  Intima-media thickness;  Ankle-brachial index;  Pulmonary function;  Correlation;  Physical examination
分类号:
R 543.5
DOI:
DOI:10.3969/j.issn.1000-7377.2023.01.009
文献标志码:
A
摘要:
目的:探讨40岁及以上体检人群肺功能和动脉硬化的相关性。方法:选取482例体检人员,根据其肺功能用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、FEV1/ FVC水平分别划分为低分位、中分位、高分位,比较不同肺功能等级体检人员双侧肱踝脉搏波传导速度(baPWV)、踝肱指数(ABI)以及颈动脉内膜中膜厚度(IMT)差异,通过Logistic回归分析肺功能和动脉硬化的关系。结果:根据肺功能FEV1水平将>98%、86%～98%、<86%者分别纳入高中低分位,baPWV、ABI水平以及颈动脉斑块形成比较,高分位<中分位<低分位(均P<0.05); 根据肺功能FVC水平将>94%、83%～94%、<83%者分别纳入高中低分位,baPWV、ABI水平以及颈动脉斑块形成比较,高分位<中分位<低分位(均P<0.05); 根据肺功能FEV1/ FVC水平将>89%、79%～89%、<79%者分别纳入高中低分位,baPWV、ABI水平以及颈动脉斑块形成比较,高分位<中分位<低分位(均P<0.05); 有序多分类Logistic回归分析结果显示影响40岁及以上体检人群肺功能水平的独立因素有baPWV水平、ABI水平、颈动脉斑块形成。结论:40岁及以上体检人群肺功能与动脉硬化相关,随着动脉硬化加重,肺通气功能呈现下降趋势。
Abstract:
Objective:To explore the correlation between pulmonary function and arteriosclerosis in health examination population over 40 years.Methods:: A total of 482 health examination objects were enrolled.According to different pulmonary function indexes [forced vital capacity(FVC),forced expiratory volume in 1 second(FEV1),FEV1/FVC],they were divided into low level,middle level and high level,respectively.The differences in bilateral brachial-ankle pulse wave velocity(baPWV),ankle-brachial index(ABI)and carotid intima-media thickness(IMT)among different pulmonary function grading were compared.The relationship between pulmonary function and arteriosclerosis was analyzed by Logistic regression analysis.Results:According to FEV1,patients with FEV1 >98%,86% to 98% and <86% were included in high,middle and low levels respectively,and the baPWV,ABI and carotid plaque formation were the highest in low level,followed by middle level and high level(all P<0.05).According to FVC,patients with FVC >94%,83% to 94% and <83% were included in high,middle and low levels respectively,and the baPWV,ABI and carotid plaque formation were the highest in low level,followed by middle level and high level(all P<0.05).According to FEV1/FVC,patients with FEV1/FVC >89%,79% to 89% and <79% were included in high,middle and low levels respectively,and the baPWV,ABI and carotid plaque formation were the highest in low level,followed by middle level and high level(all P<0.05).The results of ordered multivariate Logistic regression analysis showed that baPWV,ABI and carotid plaque formation were independent influencing factors of pulmonary function.Conclusion:Pulmonary function is related to arteriosclerosis in health examination population over 40 years.Pulmonary ventilation function is decreasing with the aggravation of arteriosclerosis.

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相似文献/References:

[1]黄德珍,徐向阳,周红梅,等.双下肢CTA和增强MRA在双下肢动脉硬化闭塞症中的对比研究[J].陕西医学杂志,2016,(09):1175.
　Huang Dezhen,Xu Xiangyang,Zhou Hongmei,et al.[J].,2016,(1):1175.

备注/Memo

备注/Memo:
基金项目:河北省医学科学研究项目(20220465)
更新日期/Last Update: 2022-12-28