[1]王 峰,党俊涛,王小峰,等.脑电双频指数联合神经胶质纤维酸性蛋白监测对重型颅脑损伤患者预后的预测价值[J].陕西医学杂志,2022,51(12):1557-1559,1563.[doi:DOI:10.3969/j.issn.1000-7377.2022.12.021]
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脑电双频指数联合神经胶质纤维酸性蛋白监测对重型颅脑损伤患者预后的预测价值
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
51
期数:
2022年12期
页码:
1557-1559,1563
栏目:
临床研究
出版日期:
2022-12-05

文章信息/Info

作者:
王 峰; 党俊涛; 王小峰; 白西民; 姚 胜; 田彩玲; 杜春亮
(渭南市中心医院神经外科,陕西 渭南 714000)
关键词:
脑电双频指数;  神经胶质纤维酸性蛋白;  颅脑损伤;  预后;  格拉斯哥昏迷量表评分
分类号:
R 651.15
DOI:
DOI:10.3969/j.issn.1000-7377.2022.12.021
文献标志码:
A
摘要:
目的:分析脑电双频指数(BIS)联合神经胶质纤维酸性蛋白(GFAP)监测对重型颅脑损伤患者预后的预测价值。方法:选取重型颅脑损伤患者160例为研究对象。所有患者均在入院后第1、3、5、7天监测BIS,同时抽取患者空腹静脉血检测血清GFAP水平。所有患者均给予手术治疗,术后6个月对所有患者进行随访,并按照格拉斯哥昏迷量表(GCS)评分将患者分为预后良好组(GOS评分≥4分)和预后不良组(GOS评分≤3分)。比较两组患者BIS及血清GFAP水平动态变化趋势。采用受试者工作特征(ROC)曲线分析BIS、GFAP单项及联合对重型颅脑损伤患者预后的预测价值。结果:两组患者入院后第1、3、5、7天血清GFAP及BIS变化趋势比较差异有统计学意义(均P<0.05)。在各时间点,预后不良组血清GFAP水平高于预后良好组,BIS低于预后良好组(均P<0.05)。ROC曲线分析显示,BIS联合GFAP对重型颅脑损伤患者预后的预测价值高于单项。结论:BIS联合GFAP监测对重型颅脑损伤患者预后具有良好的预测价值。

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备注/Memo

备注/Memo:
基金项目:陕西省渭南市科技计划项目(2019-ZDYF-SFCX-13); 陕西省渭南市首批自然科学和工程技术类青年人才支持项目
更新日期/Last Update: 2022-12-05