[1]方 圆,赵 峰,陈 佩,等.胸腔积液结核分枝杆菌感染T细胞检测对结核性胸膜炎的诊断价值研究*[J].陕西医学杂志,2020,49(12):1681-1683,1687.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.038]
 FANG Yuan,ZHAO Feng,CHEN Pei,et al.Value of T-SPOT.TB assay from pleural fIuid in diagnosis of tuberculous pleurisy[J].,2020,49(12):1681-1683,1687.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.038]
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胸腔积液结核分枝杆菌感染T细胞检测对结核性胸膜炎的诊断价值研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年12期
页码:
1681-1683,1687
栏目:
临床检验
出版日期:
2020-12-05

文章信息/Info

Title:
Value of T-SPOT.TB assay from pleural fIuid in diagnosis of tuberculous pleurisy
作者:
方 圆1赵 峰1陈 佩1吴 朔1 陈丽展2△
1.空军军医大学西京医院呼吸内科(西安 710032); 2.西安国际医学中心医院胸科医院呼吸内科(西安 710100)
Author(s):
FANG YuanZHAO FengCHEN Peiet al.
Department of Respiratory Medicine,Xijing Hospital,Air Force Medical University(Xi'an 710032)
关键词:
结核性胸膜炎 结核分枝杆菌感染T细胞检测 腺苷脱氨酶 胸腔积液 诊断效能
Keywords:
Tuberculous pleurisy T-SOPT.TB Adenosine deaminase Pleural effusion Diagnostic efficiency
分类号:
R529.3
DOI:
DOI:10.3969/j.issn.1000-7377.2020.12.038
文献标志码:
A
摘要:
目的:探讨胸腔积液结核分枝杆菌感染T细胞检测(T-SPOT.TB)对结核性胸膜炎的诊断价值。方法:选择75例胸腔积液患者为研究对象,其中结核性胸膜炎患者52例(结核组),非结核性胸膜炎患者23例(非结核组)。比较两组患者胸腔积液T-SPOT.TB、腺苷脱氨酶(ADA)及外周血T-SPOT.TB水平。通过受试者工作特征(ROC)曲线分析胸腔积液T-SPOT.TB、ADA及外周血T-SPOT.TB对结核性胸膜炎的诊断效能。结果:两组患者胸腔积液T-SPOT.TB、ADA及外周血T-SPOT.TB比较,差异均具有统计学意义(P<0.05)。在诊断结核性胸膜炎方面,胸腔积液T-SPOT.TB表现出较高的敏感度及特异度。结论:与其他检测指标相比,胸腔积液T-SPOT.TB的灵敏度和特异度较高,可以提高诊断的准确率。
Abstract:
Objective:To evalutate the value of T-SPOT.TB from pleural fIuid in the diagnosis of tuberculous pleurisy(TBP).Methods:75 patients with pleural effusion were selected as the research objects,including 52 patients with tuberculous pleurisy(tuberculosis group)and 23 patients with non tuberculous pleurisy(non tuberculosis group).The levels of T-SPOT.TB and ADA in pleural effusion and T-SPOT.TB in peripheral blood were compared between the two groups.The receiver operating characteristic(ROC)curve was used to analyze the diagnosic value of indicators above mentioned.Results:There were significant differences in T-SPOT.TB and ADA in pleural effusion and T-SPOT.TB in peripheral blood between the two groups(P<0.05).In the diagnosis of tuberculous pleurisy,T-SPOT.TB assay from pleural effusion showed higher sensitivity and specificity.Conclusion:Compared with other detection indexes,the sensitivity and specificity of T-SPOT.TB from pleural fIuid are better,which can improve diagnostic accuracy.

参考文献/References:

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备注/Memo

备注/Memo:
*国家科技重大专项课题(2017ZX10103004)
更新日期/Last Update: 2020-12-11