[1]马少君,刘延梅△,康晓丽,等.三阴性乳腺癌雄激素受体表达与X线和超声影像特征关系研究*[J].陕西医学杂志,2020,49(12):1584-1588.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.012]
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三阴性乳腺癌雄激素受体表达与X线和超声影像特征关系研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年12期
页码:
1584-1588
栏目:
临床研究
出版日期:
2020-12-05

文章信息/Info

作者:
马少君1刘延梅2△康晓丽1梁晓燕1
1.陕西省人民医院放射科(西安 710068); 2.陕西省人民医院西院二病区(西安 710068)
关键词:
三阴性乳腺癌 雄激素受体 钼靶摄影 超声
分类号:
R737.9
DOI:
DOI:10.3969/j.issn.1000-7377.2020.12.012
文献标志码:
A
摘要:
目的:探讨三阴性乳腺癌(TNBC)是否因雄激素受体(AR)不同表达而具有特征性的X线及超声表现。方法:回顾性分析101例TNBC患者的临床及影像学资料,比较AR表达状况及AR不同表达在钼靶X线摄影、超声上的差异。结果:在乳腺钼靶X线上,AR阳性TNBC多表为现肿块伴钙化或局灶不对称,AR阴性TNBC多表现为单纯肿块,两者比较差异有统计学意义(P<0.05)。AR阳性TNBC肿块形态以不规则形为主,而AR阴性TNBC肿块表现为不规则形、分叶状、圆形或椭圆形,两者比较差异有统计学意义(P<0.05)。AR阳性TNBC肿块边缘模糊多见,AR阳性TNBC钙化较多见,两者比较差异有统计学意义(P<0.05)。与AR阴性TNBC比较,AR阳性TNBC多表现为不规则肿块影或毛刺状边缘、Ki-67低表达,较少表现为浸润性导管癌和Ⅲ级组织学分级(P<0.05)。结论:AR阳性TNBC和AR阴性TNBC具有不同的影像学特征,特征性的影像学表现有助于预测AR表达状况。

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备注/Memo

备注/Memo:
*陕西省自然科学基金资助项目(2020JM-667);陕西重点研发计划项目(2020SF-056);西安市科技计划项目[2017117SF/YX011(4)]
更新日期/Last Update: 2020-12-11