[1]宋林科,周 琦,徐鑫利△.超声造影联合超声弹性成像对桥本甲状腺炎患者甲状腺结节良恶性的诊断价值[J].陕西医学杂志,2020,49(11):1472-1475.[doi:DOI:10.3969/j.issn.1000-7377.2020.11.026]
　SONG Linke,ZHOU Qi,XU Xinli..Diagnostic value of contrast-enhanced ultrasound combined with ultrasound elastography for benign and malignant thyroid nodules in patients with Hashimoto thyroiditis[J].,2020,49(11):1472-1475.[doi:DOI:10.3969/j.issn.1000-7377.2020.11.026]
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超声造影联合超声弹性成像对桥本甲状腺炎患者甲状腺结节良恶性的诊断价值
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年11期
页码:
1472-1475
栏目:
临床研究
出版日期:
2020-11-05

文章信息/Info

Title:
Diagnostic value of contrast-enhanced ultrasound combined with ultrasound elastography for benign and malignant thyroid nodules in patients with Hashimoto thyroiditis
作者:
宋林科1; 周 琦2; 徐鑫利3△
1.陕西省第四人民医院(西安 710043); 2.西安交通大学第二附属医院(西安710004); 3.陕西省铜川市人民医院(铜川 727000)
Author(s):
SONG Linke; ZHOU Qi; XU Xinli.
The Fourth People's Hospital(Xi'an 710043)
关键词:
超声造影;  超声弹性成像;  桥本甲状腺炎;  甲状腺结节;  良恶性;  诊断
Keywords:
Contrast-enhanced ultrasound;  Ultrasound elastography;  Hashimoto thyroiditis;  Thyroid nodule;  Benign and malignant;  Diagnosis
分类号:
R445.1
DOI:
DOI:10.3969/j.issn.1000-7377.2020.11.026
文献标志码:
A
摘要:
目的:研究超声造影(CU)联合超声弹性成像(UE)在桥本甲状腺炎(HT)患者甲状腺结节良恶性诊断中的应用价值。方法:纳入TI-RADS为4类的HT合并甲状腺结节患者300例,分为良性结节组和恶性结节组。对两组均进行CU和UE检查。对两组的UE、CU、UE联合CU的评分分布结果进行比较。使用ROC曲线对UE、CU、UE联合CU在HT合并甲状腺结节中的诊断价值进行分析。结果:良性结节组和恶性结节组的UE、CU以及UE联合CU评分分布比较,差异具有统计学意义(P<0.05)。ROC曲线下,UE联合CU的AUC高于CU和UE单独诊断。UE联合CU对HT患者甲状腺结节良恶性诊断的准确率明显高于UE和CU单独诊断(P<0.05)。结论:UE联合CU对TI-RADS为4类的HT合并甲状腺结节性质的诊断准确率高于单独应用UE和CU,为甲状腺结节诊断的较可靠方法。
Abstract:
Objective:To study the diagnostic value of contrast-enhanced ultrasound(CU)combined with ultrasound elastography(UE)for benign and malignant thyroid nodules in patients with Hashimoto thyroiditis(HT).Methods:300 patients with TI-RADS 4 HT combined with thyroid nodules were included and divided into benign nodules group and malignant nodules group.CU and UE inspections were performed on the two groups.The score distribution results of UE,CU,UE combined with CU in the two groups were compared.The ROC curve was used to analyze the diagnostic value of UE,CU,UE combined with CU in HT patients with thyroid nodules.Results:The comparison of the score distribution of UE,CU and UE combined with CU in the benign and malignant nodules group was statistically significant(P<0.05).The area under ROC curve of UE combined with CU in the diagnosis of benign and malignant thyroid nodules in HT patients was significantly higher than that of UE and CU alone(P<0.05).Conclusion:The diagnostic accuracy rate of UE combined with CU for TI-RADS 4 HT with thyroid nodules is higher than that of UE and CU alone,which is a reliable method for the diagnosis of thyroid nodules.

参考文献/References:

[1] Boi F,Pani F,Calo PG,et al.High prevalence of papillary thyroid carcinoma in nodular Hashimoto's thyroiditis at the first diagnosis and during the follow-up[J].Journal of Endocrinological Investigation,2018,41(4):395-402.
[2] Nathalie SDM,Stuart J,Guan H,et al.The impact of hashimoto's thyroiditis on thyroid nodule cytology & risk of thyroid cancer[J].Journal of the Endocrine Society,2019,3(4):791-800.
[3] Qin P,Wu K,Hu Y,et al.Diagnosis of benign and malignant thyroid nodules using combined conventional ultrasound and ultrasound elasticity imaging[J].IEEE Journal of Biomedical and Health Informatics,2020,24(4):1028-1036.
[4] Zhang XY,Zhang B,Jiang YX,et al.Diagnostic value of elastography for thyroid nodules in hashimoto's thyroiditis[J].Zhongguo Yi Xue Ke Xue Yuan Xue Bao,2018,40(1):59.
[5] Zhou X,Zhou P,Hu Z,et al.Diagnostic efficiency of quantitative contrast-enhanced ultrasound indicators for discriminating benign from malignant solid thyroid nodules[J].J Ultrasound Med,2018,37(2):425-437.
[6] 中华医学会内分泌学分会《中国甲状腺疾病诊治指南》编写组.中国甲状腺疾病诊治指南——甲状腺炎:亚急性甲状腺炎[J].中华内科杂志,2008,47(9):784-785.
[7] 于 璐,尚 敬,阚全娥.桥本甲状腺炎患者甲状腺良恶性结节超声特征及影响因素分析[J].中华实用诊断与治 疗杂志,2018,32(5):471-473.
[8] Giorgio R,Sandro L,Valeria D,et al.Influence of Hashimoto's thyroiditis on the development of thyroid nodules and cancer in children and adolescents[J].Journal of the Endocrine Society,2019,3(3):391.
[9] Qing H,Liu H,Jian N,et al.The diagnostic accuracy of contrast-enhanced ultrasound for the differentiation of benign and malignant thyroid nodules:a prisma compliant meta-analysis[J].Medicine,2018 2018,97(49):e13325.
[10] 巩彦星.超声造影联合超声弹性成像在甲状腺结节良恶性病变的诊断价值[J].现代诊断与治疗,2019,30(21):3842-3845.
[11] 王 琰,崔可飞,付 超,等.超声技术对桥本甲状腺炎背景下良恶性结节诊断的进展[J].广东医学,2016,37(13):2042-2045.
[12] 吕祝英,雷志锴,楼 军.超声弹性成像与常规超声对桥本氏甲状腺炎及Graves病的鉴别诊断价值分析[J].中国现代医生,2016,54(26):109-112.
[13] 康燕飞,曹春宁,李 军.超声造影联合弹性成像在甲状腺结节性病变良恶性诊断中的临床应用[J].中国现代医学杂志,2015,25(25):62-65.
[14] 王理蓉,姜 珏,贾琬莹,等.运用Logistic回归模型评价超声征象、造影模式等多因素在甲状腺结节良恶性鉴别诊断中的价值[J].现代肿瘤医学,2018,26(23):3819-3822.

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更新日期/Last Update: 2020-11-05