[1]陈瑶莉,姜 萌△.内镜黏膜隧道肿瘤切除术治疗食管固有肌层黏膜肿瘤疗效研究[J].陕西医学杂志,2020,49(8):991.[doi:DOI:10.3969/j.issn.1000-7377.2020.08.020]
　CHEN Yaoli,JIANG Meng..Effect of submucosal tunnel endoscopic resection in the treatment of esophageal muscularis mucosal tumors[J].,2020,49(8):991.[doi:DOI:10.3969/j.issn.1000-7377.2020.08.020]
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内镜黏膜隧道肿瘤切除术治疗食管固有肌层黏膜肿瘤疗效研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年8期
页码:
991
栏目:
临床研究
出版日期:
2020-08-05

文章信息/Info

Title:
Effect of submucosal tunnel endoscopic resection in the treatment of esophageal muscularis mucosal tumors
作者:
陈瑶莉; 姜 萌△
陕西省铜川市人民医院(铜川 727100)
Author(s):
CHEN Yaoli; JIANG Meng.
Tongchuan People's Hospital,Shaanxi Province(Tongchuan 727100)
关键词:
食管;  固有肌层黏膜肿瘤;  内镜黏膜隧道肿瘤切除术;  内镜黏膜下肿瘤挖除术;  生活质量;  并发症
Keywords:
Esophagus;  Intrinsic muscular mucosa tumor;  Submucosal tunnel endoscopic resection;  Endoscopic submucosal excavation;  Quality of life;  Complications
分类号:
R735.1
DOI:
DOI:10.3969/j.issn.1000-7377.2020.08.020
文献标志码:
A
摘要:
目的:探讨内镜黏膜下隧道肿瘤切除术治疗食管固有肌层黏膜肿瘤的效果。方法:106例食管固有肌层黏膜肿瘤患者,按不同术式分为对照组、观察组两组,各53例。对照组行内镜黏膜下肿瘤挖除术(ESE),观察组采用内镜黏膜下隧道肿瘤切除术(STER)治疗,对比两组手术指标和随访结果变化。结果:观察组手术时间和住院时间短于对照组且术中输血量少于对照组(P<0.05),两组术中钛夹使用量和根治性手术率比较无统计学差异(P>0.05); 术后两组并发症发生情况比较差异无统计学意义(P>0.05); 两组出院后6月和1年随访结果发现其肿瘤残留及复发情况比较无统计学差异(P>0.05); 经相应治疗后6个月,两组SF-36量表中生理功能、生理职能以及情感角色等评分比较无统计学差异(P>0.05),观察组躯体疼痛和活动能力评分均显著高于对照组(P<0.05)。结论:以STER和ESE治疗食管固有肌层黏膜肿瘤可获得良好效果,但STER术创伤更小,术后患者恢复更快,可减轻患者疼痛,提高日常活动能力。
Abstract:
Objective:To analyze the effect of endoscopic mucosal tunnel tumor resection in the treatment of esophageal muscularis mucosa tumors.Methods:106 patients with esophageal muscularis mucosal tumors were divided into control group and observation group according to different operation methods,53 cases in each group.The control group was treated with endoscopic submucosal excavation(ESE),and the observation group was treated with submucosal tunnel endoscopic resection(STER).The changes in surgical indicators and follow-up results were compared between the two groups.Results:The operation time and hospitalization time of the observation group were shorter than those of the control group,and the intraoperative blood transfusion volume was less than that of the control group(P<0.05).There was no statistical difference between the use of titanium clips and the radical operation rate between the two groups(P>0.05).There was no significant difference in the incidence of complications between the two groups after surgery(P>0.05).The follow-up results of the two groups at 6 months and 1 year after discharge were found that there was no significant difference in the tumor residue and recurrence(P>0.05).Six months after the corresponding treatment,there was no significant difference in the scores of physical function,role physical and role emotional between the two groups of SF-36 scales(P>0.05),and the bodily pain and vitality scores of the observation group were significantly higher than those of the control group(P<0.05).Conclusion:STER and ESE can be used to treat esophageal muscularis mucosa tumors with good results,but the trauma of STER is smaller,the recovery of patients is faster,the pain of patients can be reduced,and the ability of daily activities can be improved.

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更新日期/Last Update: 2020-08-04