[1]尹 梅.喘息性支气管炎患儿红细胞分布宽度与其预后相关性研究[J].陕西医学杂志,2020,49(7):841-843896.[doi:DOI:10.3969/j.issn.10007377.2020.07.020]
　YIN Mei..Correlation between red cell distribution width and prognosis in children with asthmatic bronchitis[J].,2020,49(7):841-843896.[doi:DOI:10.3969/j.issn.10007377.2020.07.020]
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喘息性支气管炎患儿红细胞分布宽度与其预后相关性研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年7期
页码:
841-843896
栏目:
临床研究
出版日期:
2020-07-05

文章信息/Info

Title:
Correlation between red cell distribution width and prognosis in children with asthmatic bronchitis
作者:
尹 梅
西安市儿童医院特需科(西安 710003)
Author(s):
YIN Mei.
The Special Department of Xi'an Children's Hospital(Xi'an 710003)
关键词:
支气管炎;  喘息;  儿童;  治疗;  复发;  红细胞分布宽度
Keywords:
Bronchitis;  Wheezing;  Children;  Treatment;  Relapse;  Red cell distribution width
分类号:
R725.6
DOI:
DOI:10.3969/j.issn.10007377.2020.07.020
文献标志码:
A
摘要:
目的:探究喘息性支气管炎患儿血清红细胞分布宽度(RDW)与常规治疗后复发的相关性。方法:选择喘息性支气管炎患儿126例为研究对象,给予患儿常规的平喘抗炎、抗感染、吸氧、静脉注射免疫球蛋白、雾化吸入硫酸特布他林气雾剂等治疗14 d后,评估患儿临床效果,随访观察患儿疾病复发情况。按照是否复发将患儿分为有效和复发两组。单因素和Logistic回归分析法分析喘息性支气管炎患儿复发的危险因素。ROC曲线分析RDW对常规治疗后患儿复发率的预测价值。结果:126例患儿经治疗后12例(9.52%)复发。基线资料比较显示,复发患儿被动吸烟和具有家族喘息病史者占比明显高于治疗有效患儿(P<0.05),血清RDW和IgE水平低于治疗有效患儿(P<0.01)。Logistic回归分析,结果显示,被动吸烟、家族哮喘病史、血清RDW和IgE是喘息性支气管炎患儿病情复发的独立预测因子(P<0.05),RDW的曲线下面积(AUC)为0.705(P<0.05,95%CI 0.554～0.856),约登指数为0.391,预测患儿疾病复发的灵敏度0.833,特异度0.621。结论: RDW是喘息性支气管炎患儿常规治疗后复发的意向独立预测因子。
Abstract:
Objective:To explore the correlation between red cell distribution width(RDW)and relapse after routine treatment in children with asthmatic bronchitis. Methods:A total of 126 children with asthmatic bronchitis were selected as the research subjects. The children were treated with conventional antiasthma,anti-infection,oxygen inhalation,intravenous immunoglobulin,aerosol inhalation of terbutaline sulfate aerosol and other methods for 14 days. The clinical effect of the children was evaluated,and the recurrence of the disease was followed up. The children were divided into effective group and recurrent group according to whether they relapsed or not. Univariate analysis and Logistic regression analysis were used to analyze the risk factors of relapse in children with asthmatic bronchitis. The predictive value of RDW on the recurrence rate of children after routine treatment was analyzed by ROC curve. Results:12 cases(9.52%)relapsed after treatment. Baseline data comparison showed that the proportion of children with passive smoking and family history of wheezing in recurrent group was significantly higher than those in effective group(P<0.05),and serum RDW and IgE levels were lower than those in effective treatment(P<0.01). Logistic regression analysis showed that passive smoking,family history of asthma,serum RDW and IgE were independent predictors of relapse in children with asthmatic bronchitis(P<0.05),and the AUC of RDW was 0.705(P<0.05,95%CI 0.554-0.856),and the Youden index was 0.391,and the sensitivity of predicting disease recurrence in children was 0.833,and the specificity was 0.621. Conclusion:RDW is an independent predictor of relapsing in children with asthmatic bronchitis after routine treatment.

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更新日期/Last Update: 2020-07-28