[1]文 栋,王西宾△.99Tcm-MDP全身骨扫描及局部单光子发射计算机断层成像在骨转移性肿瘤诊断中的临床应用*[J].陕西医学杂志,2020,49(7):808-810814.[doi:DOI:10.3969/j.issn.10007377.2020.07.010]
　WEN Dong,WANG Xibin..Diagnostic value of 99Tcm-MDP whole body bone scan and local SPECT in bone metastatic tumors[J].,2020,49(7):808-810814.[doi:DOI:10.3969/j.issn.10007377.2020.07.010]
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99Tcm-MDP全身骨扫描及局部单光子发射计算机断层成像在骨转移性肿瘤诊断中的临床应用*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年7期
页码:
808-810814
栏目:
临床研究
出版日期:
2020-07-05

文章信息/Info

Title:
Diagnostic value of 99Tcm-MDP whole body bone scan and local SPECT in bone metastatic tumors
作者:
文 栋; 王西宾△
陕西省汉中市中心医院核医学科(汉中723000)
Author(s):
WEN Dong; WANG Xibin.
Department of Nuclear Medicine,Hanzhong Central Hospital,Shaanxi Province(Hanzhong 723000)
关键词:
99Tcm-MDP全身骨扫描;  局部单光子发射计算机断层;  骨转移;  肿瘤;  诊断;  准确性
Keywords:
99Tcm-MDP whole body bone scan;  Local SPECT;  Bone metastasis;  Tumor;  Diagnosis;  Accuracy
分类号:
R738.1
DOI:
DOI:10.3969/j.issn.10007377.2020.07.010
文献标志码:
A
摘要:
目的:探究99Tcm-MDP全身骨扫描以及局部单光子发射计算机断层成像(SPECT)在骨转移性肿瘤中的诊断价值。方法:选择81例疑似肿瘤骨转移患者作为研究对象,分别对其实施了99Tcm-MDP全身骨扫描和局部SPECT检测,以病理学检测结果为金标准,分别探究99Tcm-MDP全身骨扫描和局部SEPCT对肿瘤骨性转移的诊断一致性、灵敏度、特异度、阳性预测值和阴性预测值,并实施组间诊断价值比较。结果:①99Tcm-MDP全身骨扫描对骨转移性肿瘤诊断一致性为69.14%,灵敏度为70.00%,特异度为67.74%,阳性预测值为77.78%,阴性预测值为58.33%; ②局部SPECT对骨转移肿瘤诊断一致性为92.59%,灵敏度为92.00%,特异度为93.55%,阳性预测值为95.83%,阴性预测值为93.55%; ③两种检测方式比较发现,局部SEPCT对骨转移性肿瘤诊断的一致性、灵敏度、特异度、阳性预测值和阴性预测值均高于99Tcm-MDP全身骨扫描,且比较差异有统计学意义(P<0.05)。结论:相比于99Tcm-MDP全身骨扫描,局部SPECT检测对骨转移性肿瘤诊断更为准确敏感,值得临床应用。
Abstract:
Objective:To explore the diagnostic value of 99Tcm-MDP whole body bone scan and local single photon emission computed tomography(SPECT)in bone metastatic tumor. Methods:A total of 81 patients with suspected tumor bone metastase were selected as the research subjects. 99Tcm-MDP whole body bone scan and local SPECT were performed on them respectively. With pathological detection results as the gold standard,the diagnostic consistency,sensitivity,specificity,positive predictive value and negative predictive value of 99Tcm-MDP whole body bone scan and local SEPCT in bone metastatic tumor were explored and compared. Results:The diagnostic consistency of 99Tcm-MDP whole body bone scan for bone metastatic tumor was 69.14%,the sensitivity was 70.00%,the specificity was 67.74%,the positive predictive value was 77.78%,and the negative predictive value was 58.33%. The diagnostic consistency of local SPECT for bone metastatic tumor was 92.59%,the sensitivity was 92.00%,the specificity was 93.55%,the positive predictive value was 95.83%,and the negative predictive value was 93.55%. The diagnostic consistency,sensitivity,specificity,positive predictive value and negative predictive value of local SEPCT in bone metastatic tumor were higher than 99Tcm-MDP whole body bone scan,with significant differences(P<0.05). Conclusion:Compared with 99Tcm-MDP whole body bone scan,local SPECT is more accurate and sensitive in the diagnosis of bone metastatic tumor diagnosis.

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备注/Memo

备注/Memo:
*陕西省卫生和计划生育委员会科研基金资助项目(2016C005)
更新日期/Last Update: 2020-07-28