[1]田 鹏,蔡盈盈,孙春丽,等.衰弱对社区老年人骨折预测作用的系统评价[J].陕西医学杂志,2020,49(3):370-374.
点击复制

衰弱对社区老年人骨折预测作用的系统评价
分享到：

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年3期
页码:
370-374
栏目:
Meta分析
出版日期:
2020-03-05

文章信息/Info

文章编号:
DOI:〖HT5K〗10.3969/j.issn.10007377.2020.03.027
作者:
田 鹏; 蔡盈盈; 孙春丽; 彭朝明
成都医学院第一附属医院(成都 610500)
关键词:
衰弱;  骨折;  预测;  系统评价;  社区
分类号:
R592
文献标志码:
A
摘要:
目的:确定衰弱与社区老年人骨折的相关性,作为社区老年人骨折的预测指标。方法: 使用Embase(OVID)、Pubmed、Cochrane Library、Wan Fang、CNKI和VIP数据库进行全面检索,搜索2000年1月至2019年1月发表的衰弱与骨折风险之间关系的前瞻性队列研究。两位研究人员独立从文献中提取数据优势比(OR)、风险比(RR)和危险比(HR),采用STATA统计学软件进行分析。结果:最终纳入7项研究,共97640例社区老年人。以OR为指标的研究异质性检验(I2=79.5%,P=0.000),随机效应模型合并后,衰弱增加骨折的风险[OR=1.722,95%CI(1.222～2.426),P=0.002]; 异质性检验(I2=39%,P=0.194),固定效应模型合并后,衰弱前期不能增加社区老年人骨折的风险[OR=1.178,95%CI(0.972～1.429),P=0.094]。以HR为指标的研究,异质性检验(I2=64%,P=0.095),随机效应模型合并后,衰弱增加骨折的风险[OR=1.529,95%CI(0.837～2.221),P=0.000],异质性检验(I2=41.9%,P=0.190),固定效应模型合并后,衰弱前期增加社区老年人骨折的风险[OR=1.063,95%CI(0.789～1.338),P=0.000]。结论:系统评价表明,衰弱是社区老年人骨折的预测因子,衰弱前期与骨折的关系需进一步验证。

参考文献/References:

[1] Rockville.Methods guide for effectiveness and comparative effectiveness reviews[J].Agency for Healthcare Research and Quality,2013,10:109.
[2] Van den Bergh JP,Van Geel TA,Geusens PP.Osteoporosis,frailty and fracture:implications for case finding and therapy[J].Nat Rev Rheumatol, 2012,8(3):163-172.
[3] Fredric D,Wolinsky Suzanne E.Recent hospitalization and the risk,Hip fractures among older Americans[J].J Gerontology,2009,64A(2):249-255.
[4] NIH Consensus Development Panel on Osteoporosis Prevention D,and Therapy.Osteoporosis prevention,diagnosis,and therapy[J].JAMA,2001,285(6):785-795.
[5] Clegg A,Young J,Iliffe S,et al.Frailty in elderly people[J].Lancet(London,England),2013,381(9868):752-762.
[6] Kojima G.Frailty as a predictor of future falls among community-dwelling older people:a systematic review and meta-analysis[J].Am Med Dir Assoc,2015,16(12):1027-1033.
[7] Kojima G.Frailty as a predictor of hospitalisation among community-dwelling older people:a systematic review and meta-analysis[J].Epidemiol Community Health,2016,70(7):722-729.
[8] Kojima G,Iliffe S,Jivraj S,et al.Association between frailty and quality of life among community-dwelling older people:a systematic review and meta-analysis[J].Epidemiol Community Health,2016,70(7):716-721.
[9] Rolland Y,van Kan G A,Benetos A,et al.Frailty,osteoporosis and hip fracture:causes,consequences and therapeutic perspectives[J].Nutr Health Aging,2008,12(5):335-346.
[10] Sternberg SA,Levin R,Dkaidek S,et al.Frailty and osteoporosis in older women-a prospective study,Osteoporos[J].Int,2014,25(2):763-768.
[11] Ma SL,Oyler J,Glavin S,et al.Self-reported frailty is associated with low calcaneal bone mineral density in a multiracial population of community-dwelling elderly,Osteoporos[J].Int,2009,20(11):1837-1846.
[12] Fried LP,Tangen CM,Walston J,et al.Frailty in older adults:evidence for a phenotype[J].Gerontol A Biol Sci Med Sci,2001,56(3):146-156.
[13] de Vries OJ,Peeters GMEE,Lips P,et al.Does frailty predict increased risk of falls and fractures? A prospective population-based study[J].Osteoporos Int,2013,24:2397-2403.
[14] Kristine E, Ensrud Susan K, Ewing Peggy M,et al.A Comparison of frailty indexes for the prediction of falls,disability,fractures,and mortality in older men[J].JAGS,2009,57:492-498.
[15] Forti P,Rietti E,Pisacane N,et al.A comparison of frailty indexes for prediction of adverse health outcomes in an elderly cohort[J].Archives of Gerontology and Geriatrics,2012,54:16-20.
[16] Guowei Li,Thabane L,Papaioannou A,et al.Comparison between frailty index of deficit accumulation and fracture risk assessment tool(FRAX)in prediction of risk of fractures[J].Bone,2016,10:1-21.
[17] Sarah ET,Jonathan D, AdachiFrederick A,et al.Frailty and fracture,disability,and Falls:A multiple country study from the global longitudinal study of osteoporosis in women[J].JAGS,2013,53:327-334.
[18] Woods NF,La Croix AZ,Gray SL,et al.Frailty:emergence and consequences in women aged 65 and older in the women's health initiative observational study[J].JAGS,2005,8:1321-1330.
[19] Zaslavsky O,Zelber-Sagi S,Gray L,et al.Comparison of frailty phenotypes for prediction of mortality,incident falls,and hip fracture in older women[J].JAGS,2016,64(9):1858-1862.
[20] Collard RM,Boter H,Schoevers RA,et al. Prevalence of frailty in community-dwelling older persons:a systematic review[J].J Am Geriatr Soc,2012,60:1487.
[21] 田 鹏,杨 宁,郝秋奎,等.中国老年衰弱患病率的系统评价[J].中国循证医学杂志,2019,6(19):656-664.
[22] Xue QL.The frailty syndrome:definition and natural history[J].Clin Geriatr Med,2011,27(1):1-15.
[23] Clegg A,Young J,Iliffe S,et al.Frailty in elderly people[J].Lancet,2013,381(9868):752-762.
[24] Kiely DK,Cupples LA,Lipsitz LA.Validation and comparison of two frailty indexes:The MOBILIZE Boston Study[J].J Am Geriatr Soc,2009,57:1532.
[25] 王宇强,苏学涛,赵永军,等.血清铁过载与老年女性骨质疏松性骨折的关系研究[J].陕西医学杂志,2016,45(12):1596-1597.
[26] Dargent-Molina P,Favier F,Grandjean H,et al.Fall-related factors and risk of hip fracture:the EPIDOS prospective study[J].Lancet,1996,348:145-149.
[27] Kojima G.Frailty as a predictor of fractures among community-dwelling older people:A systematic review and meta-analysis[J].Bone,2016,90:116-122.

相似文献/References:

[1]梁朝鑫,周安远,吴立蔚,等.富血小板血浆在骨科疾病治疗中的研究进展[J].陕西医学杂志,2021,50(12):1605.[doi:DOI:10.3969/j.issn.1000-7377.2021.12.035]
　LIANG Chaoxin,ZHOU Anyuan,WU Liwei,et al.Research progress of platelet-rich plasma in treatment of orthopedic diseases[J].,2021,50(3):1605.[doi:DOI:10.3969/j.issn.1000-7377.2021.12.035]
[2]彭 赛,卢丛兰,孙中洋.人工智能在骨质疏松症诊疗中的应用进展[J].陕西医学杂志,2024,(3):425.[doi:DOI:10.3969/j.issn.1000-7377.2024.03.030]
　PENG Sai,LU Conglan,SUN Zhongyang.Advances in application of artificial intelligence in diagnosis and treatment of osteoporosis[J].,2024,(3):425.[doi:DOI:10.3969/j.issn.1000-7377.2024.03.030]

更新日期/Last Update: 2020-03-25