[1]李江涛,华爱玲,赵竹莉.呼吸机肺保护性通气联合人免疫球蛋白治疗〖JZ〗重症肺炎合并呼吸衰竭疗效研究*[J].陕西医学杂志,2019,(10):1302-1304.
　LI Jiangtao,HUA Ailing,ZHAO Zhuli..Effect of ventilatorlung protective ventilation combined with 〖JZ〗human immunoglobulin on severe pneumonia with respiratory failure[J].,2019,(10):1302-1304.
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呼吸机肺保护性通气联合人免疫球蛋白治疗〖JZ〗重症肺炎合并呼吸衰竭疗效研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年10期
页码:
1302-1304
栏目:
临床研究
出版日期:
2019-10-05

文章信息/Info

Title:
Effect of ventilatorlung protective ventilation combined with 〖JZ〗human immunoglobulin on severe pneumonia with respiratory failure
文章编号:
DOI:10.3969/j.issn.10007377.2019.10.015
作者:
李江涛; 华爱玲; 赵竹莉
西安交通大学第一附属医院（东院）急诊科 (西安 710089)
Author(s):
LI Jiangtao; HUA Ailing; ZHAO Zhuli.
Emergency Department,〖JZ〗The First Affiliated Hospital Of Xi'an Jiaotong University(East Hospital)（Xi’an 710089）
关键词:
肺保护性通气; 人免疫球蛋白; 重症肺炎; 呼吸衰竭; 疗效; 炎性因子; 免疫功能
Keywords:
Key words 〖WT5BZ〗〖HT5”SS〗Pulmonary protective ventilation; Human immunoglobulin; Severe pneumonia; Respiratory failure; Curative effect; Inflammatory factors; Immune function
分类号:
R563
文献标志码:
A
摘要:
摘 要 目的：分析呼吸机肺保护性通气联合人免疫球蛋白对重症肺炎合并呼吸衰竭的疗效。方法:选择59例重症肺炎合并呼吸衰竭患者，随机分为两组。对照组采用呼吸机肺保护性通气，观察组联用人免疫球蛋白。结果:两组治疗后的呼吸频率、血气指标和心率明显改善(P＜0.05)；观察组治疗后的血清IL6、TNFα和IL8水平明显低于对照组(P＜0.05)，IgA、IgM及IgG水平明显高于对照组(P＜0.05)；观察组住院期间的死亡率明显低于对照组(P＜0.05)。结论:呼吸机肺保护性通气联合人免疫球蛋白对重症肺炎合并呼吸衰竭的疗效显著。 
Abstract:
Abstract 〖WT5BZ〗〖HT5”SS〗Objective:To study the effect of ventilatorlung protective ventilation combined with human immunoglobulin on severe pneumonia with respiratory failure.Methods:59 cases of patients with severe pneumonia and respiratory failure were divided into two groups randomly.The control group was treated with ventilator lung protective ventilation, the observation group was treated with human immunoglobulin.Results Respiratory frequency, blood gas index and heart rate were significantly improved in both groups(P＜0.05).The serum levels of IL6, TNFalpha and IL8 in the observation group after treatment were significantly lower than control group(P＜0.05), and the levels of IgA, IgM and IgG were significantly higher than control group(P＜0.05); the mortality rate in the observation group was significantly lower than control group(P＜0.05).Conclusion Respiratory ventilation combined with human immunoglobulin has a significant effect on severe pneumonia with respiratory failure.

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备注/Memo

备注/Memo:
*陕西省社会发展科技攻关项目（2015SF057）
更新日期/Last Update: 2019-10-23