[1]张春谊,廖习坪△,刘 蕊,等.头颈癌患者股前外侧皮瓣修复术后高蛋白营养支持治疗疗效观察[J].陕西医学杂志,2019,(9):1190-1193.
　ZHANG Chunyi,LIAO Xiping,LIU Rui,et al.Effect observation of highprotein nutritional support after anterolateral femoral〖JZ〗flap repair in patients with head and neck cancer[J].,2019,(9):1190-1193.
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头颈癌患者股前外侧皮瓣修复术后高蛋白营养支持治疗疗效观察
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年9期
页码:
1190-1193
栏目:
临床研究
出版日期:
2019-09-05

文章信息/Info

Title:
Effect observation of highprotein nutritional support after anterolateral femoral〖JZ〗flap repair in patients with head and neck cancer
文章编号:
DOI:〖HT5K〗10.3969/j.issn.10007377.2019.09.022
作者:
张春谊1; 廖习坪1△; 刘 蕊2; 申红艳1; 蔡红萍1; 刘 婵1
1.空军军医大学第三附属医院颌面肿瘤科（西安710032）； 〖JZ〗2.空军军医大学第三附属医院护理处（西安710032）
Author(s):
ZHANG Chunyi; LIAO Xiping; LIU Rui; et al.
Department of Maxillofacial Oncology， 〖JZ〗Third Affiliated Hospital of Air Force Military Medical University( Xi’an 710032)
关键词:
营养支持治疗; 头颈癌; 营养状况; 股前外侧皮瓣修复术; 手术并发症
Keywords:
Key words 〖WT5BZ〗〖HT5”SS〗Nutritional support therapy; Head and neck cancer; Nutritional status; Repair of anterolateral femoral flap; Surgical complications
分类号:
R737.31
文献标志码:
A
摘要:
摘 要 〖HT5K〗目的：观察肠内高蛋白营养支持治疗对头颈癌患者股前外侧皮瓣修复术后的营养状况与治疗效果。方法：选取头颈癌患者47例，将其随机分为对照组（n=21）与试验组（n=26）。在接受常规治疗干预外，试验组选用流食+蛋白粉\[2.0g/（kg·d）\]进行肠内营养支持，对照组仅自备流食。若出现胃肠道症状，则辅以活性益生菌进行胃肠道调理，要求两组患者每日摄食量相同。记录两组患者术后当天、术后第10天的营养指标（TP、ALB、PA）及免疫指标（WBC、LYM、NEU）差异；及术后腹泻、腹胀及切口感染的发生率。结果：两组患者入院时、术后当日各指标接近，利于对照研究。术后第10天，试验组病例TP、ALB、PA较对照组有明显升高（P＜0.01）；试验组WBC、LYM、NEU数量较对照组更快恢复至正常水平（P＜0.05）；试验组术后腹泻、腹胀及伤口感染发生率较对照组明显降低（P＜0.05）。结论：流质饮食+高水平蛋白粉进行鼻饲喂养，可明显改善头颈癌患者术后营养状况，降低腹泻、腹胀及切口感染的发生率。
Abstract:
Abstract 〖WT5BZ〗〖HT5”SS〗Objective：to observe the nutritional status and therapeutic effect of enteral highintaking protein powder nutritional support therapy on patients with head and neck cancer after anterolateral femoral flap repaired. Methods：47 patients with head and neck cancer were randomly divided into the control group (n=21) and the test group (n=26).In addition to receiving conventional treatment and nursing，the test group used liquid food + protein powder\[2.0g/（kg·d）\] for enteral nutrition support，while the control group only prepared liquid food，requiring the two groups to eat the same amount of food every day.Serum protein content (TP，ALB，PA) and blood cell count (WBC，LYM，NEU) of the two groups were recorded on the day after surgery and the 10th day after surgery.Postoperative diarrhea，abdominal distension and incisional infection. Results:the indexes of the two groups were close to each other on the day after the operation，which was in line with the control principle and conducive to the comparison.On the 10th day after surgery，TP，ALB and PA in the test group were significantly higher than those in the control group (P＜0.01).The number of WBC，LYM and NEU in the test group recovered to the normal level faster than that in the control group (P＜0.05).The incidence of postoperative diarrhea，abdominal distension and wound infection in the test group was significantly lower than that in the control group (P＜0.05).Conclusion：Highintaking protein powder combined with liquid diet can significantly improve the perioperative nutritional status of patients with head and neck cancer，and reduce the incidence of diarrhea，abdominal distension and incision infection.

参考文献/References:

[1] 〖ZK（#〗杨雪蓝，席淑新.近10年我国人群营养风险筛查研究现状文献计量学分析[J] .解放军护理杂志,2018,35(21):2427.
[2] Ting Z,Shiying Y.Advances in the diagnosis and treatment of patients with cancer cachexia[J] .Oncology and Translational Medicine,2018,4(4):133143.
[3] Amitabha R.Cancer and comorbidity:The role of leptin in breast cancer and associated pathologies[J] .World Journal of Clinical Cases,2018,6(12):483492. 
[4] 石汉平.营养治疗的疗效评价[J] .肿瘤代谢与营养电子杂志,2017,4(4):364370.
[5] Jon C,Francisco C,Lorea MI,et al.A prospective analysis of factors that influence weight loss in patients undergoing radiotherapy[J] .Chinese Journal of Cancer,2014,33(4):204210.
[6] Shailesh MG,Rahul RB,Amol RG,et al.Quality of life and oral potentially malignant disorders：Critical appraisal and prospects[J] .World Journal of Clinical Oncology,2018,9(4):5659.
[7] 王晓燕,王永军,李腊梅,等.早期肠内营养支持对老年胃底贲门癌患者术后营养状况及机体恢复的影响[J] .陕西医学杂志,2017,46(10):13901391.
[8] Ji Z,Fan G,AnKui Y,et al.Epidemiologic characteristics of oral cancer:singlecenter analysis of 4097 patients from the sun yatsen university cancer center[J] .Chinese Journal of Cancer,2016,35(4):190195. 
[9] 曹子谦,李树营,任 宏,等.胃癌根治术后患者营养风险筛查及其行早期肠内营养支持和肠外营养支持的效果对比[J] .陕西医学杂志,2018,47(10):12721274,1293.〖ZK)〗
[10] 〖ZK(#〗陈 斌,董海胜,张国文,等.特殊医学用途配方食品及其应用研究[J] .食品科学技术学报,2017,35(1):616. 
[11] Yu J，Yu F，Cao X. Effect of wholecourse nutritional support therapy on acute radiation response，tolerance and efficacy of cervical cancer patients [J] . Journal of Clinical Oncology，2008,23(7):635639. 
[12] Mingchao F,Qiaoling W,Wei F,et al.Early enteral combined with parenteral nutrition treatment for severe traumatic brain injury：Effects on immune function，nutritional status and outcomes[J] .Chinese Medical Sciences Journal,2016,31(4):213220. 
[13] 张春谊,刘 蕊,廖习坪,等.围手术期肠内营养支持对舌癌患者营养状况及生存质量的影响\[J/OL\].现代肿瘤医学,2019,(5):766770.
[14] 胡志萍,段玮玮,雷文鸽,等.头颈部恶性肿瘤病人生存质量及其影响因素调查[J] .护理研究,2018,32(5):725730.
[15] LiJu C,HuanLin C,MingJong B,et al.Refeeding syndrome in Southeastern Taiwan:Our experience with 11 cases[J] .World Journal of Gastroenterology,2014,20(30):1052510530. 
[16] 肖 华,杨维军,施雪松,等.早期肠内营养对结肠癌患者术后免疫功能和康复的影响[J] .陕西医学杂志,2016,45(12):16551657.
[17] 李小玲.社会支持与头颈癌患者生存质量的相关性研究[J] .当代护士：中旬刊,2017，(2):8890.

更新日期/Last Update: 2019-09-24