[1]林丹丹,黄建玲,卢伊玲.B超、超敏C反应蛋白及血脂水平联合检查在高龄H型高血压患者颈动脉血管斑块稳定性诊断的应用价值*[J].陕西医学杂志,2019,(7):838-841.
　LIN Dandan,HUANG Jianling,LU Yiling..Application value analysis of B-mode ultrasound，hypersensitive c-reactive protein and blood lipid levels in the diagnosis of carotid artery plaque stability in elderly patients with H-type hypertension[J].,2019,(7):838-841.
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B超、超敏C反应蛋白及血脂水平联合检查在高龄H型高血压患者颈动脉血管斑块稳定性诊断的应用价值*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年7期
页码:
838-841
栏目:
临床研究
出版日期:
2019-07-05

文章信息/Info

Title:
Application value analysis of B-mode ultrasound，hypersensitive c-reactive protein and blood lipid levels in the diagnosis of carotid artery plaque stability in elderly patients with H-type hypertension
文章编号:
DOI:10.3969/j.issn.1000-7377.2019.07.006
作者:
林丹丹; 黄建玲; 卢伊玲
广西自治区钦州市第二人民医院超声诊断科（钦州535000）
Author(s):
LIN Dandan; HUANG Jianling; LU Yiling.
Ultrasound Diagnosis Department， Qinzhou Second People’s Hospital，Guangxi Autonomous Region (Qinzhou 535000)
关键词:
H型高血压; 彩色多普勒超声; 超敏C反应蛋白; 血脂; 颈动脉血管斑块; 应用价值
Keywords:
Key words Type hypertension;  Color doppler ultrasound;  Hypersensitive c-reactive protein;  Blood lipid;  Carotid artery plaque; The actual value
分类号:
R544.1
文献标志码:
A
摘要:
摘 要 目的：研究B型超声、超敏C反应蛋白（hs-CRP）及血脂水平在高龄H型高血压患者颈动脉血管斑块稳定性诊断的应用价值。方法：选择150例老年高血压患者作为观察对象，将其按照年龄以及同型半胱氨酸水平的不同分成高龄H型高血压组、低龄H型高血压组，低龄非H型高血压组，另取同期接受体检的健康人员100例为对照组。分别采用彩色多普勒超声诊断仪检测各组人员的颈动脉斑块信息，采用酶联免疫吸附法检测hs-CRP水平，采用日立7600型全自动生化分析仪检测血脂指标水平。并分析H型高血压患者颈动脉斑块结构与年龄、血清H型高血压以及血脂水平的相关性。结果：高龄H型高血压组、低龄H型高血压组、低龄非H型高血压组、对照组颈动脉血管不稳定性斑块发生率呈逐渐降低趋势，且经单因素方差分析可得：各组间对比差异有统计学意义（均P＜0.05）。高龄H型高血压组、低龄H型高血压组、低龄非H型高血压组、对照组血清hs-CRP、低密度脂蛋胆固醇（LDL-C）水平呈逐渐降低趋势，且经单因素方差分析可得：各组间对比差异均有统计学意义（均P＜0.05）。经Pearson相关性分析可得：高龄H型高血压患者颈动脉血管不稳定斑块与年龄、hs-CRP、LDL-C水平呈正相关关系（均P＜0.05）。结论：B型超声、hs-CRP及血脂水平联合检测可用于诊断高龄H型高血压患者颈动脉血管斑块稳定性情况。
Abstract:
Abstract Objective: To investigate the value of B-mode ultrasound，hypersensitive c-reactive protein (hs-CRP) and blood lipid levels in the diagnosis of carotid artery plaque stability in elderly patients with h-type hypertension.Methods: 150 cases of senile hypertension patients as research object，its according to age and homocysteine levels were divided into the elderly H hypertension group，the young H hypertension group,the young non H hypertension group，another the same period in the health checkup in our personnel 100 cases were seletctd as the control group. Carotid artery plaque information of each group was detected by color doppler ultrasound diagnostic instrument，hs-CRP level was detected by enzyme linked immunosorbent assay，and serum lipid level was detected by Hitachi 7600 automatic biochemical analyzer. The relationship between carotid artery plaque structure and age，serum h-type hypertension and blood lipid level in patients with h-type hypertension was analyzed.Results: The incidence of carotid artery instability plaque in the elderly H hypertension group，the young H hypertension group，the young non H hypertension group，and the control group showed a gradually decreasing trend，and one-way anova showed that there were statistically significant differences between the groups (all P＜0.05).The serum hs-CRPand LDL-C levels of the elderly H hypertension group，the young H hypertension group,the young non H hypertension group and the control group showed a gradually decreasing trend，and one-way anova showed that there were statistically significant differences between the groups (all P＜0.05).Pearson correlation analysis showed that carotid artery plaque instability was positively correlated with age，hs-CRP and LDL-C levels in elderly patients with type H hypertension (all P＜0.05).Conclusion: Combined B-mode ultrasound，hs-CRP and lipid level detection can be used to diagnose〖LM〗 the stability of carotid artery plaque in elderly patients with h-type hypertension.

参考文献/References:

[1] Pang H，Han B，Fu Q,et al.Association between homocysteine and conventional predisposing factors on risk of stroke in patients with hypertension[J].Sci Rep,2018,8(1):3900-3900. [2] 江 洪,钟诗颖,韦 明,等.布洛陀壮族H型高血压与颈动脉粥样斑块的相关性[J].心肺血管病杂志,2018,37(9):827-830. [3] 方 宇,刘惠莲,杨克平,等.H型高血压患者血管的结构功能及其血栓前分子标记物的变化[J].血栓与止血学,2018,24(2):197-200. [4] 李青华.H型高血压并发急性脑梗死同型半胱氨酸水平升高的危险因素分析[J].中国实用神经疾病杂志,2018,21(4):410-413. [5] 周 康,殷 音,彭 毅,等.高血压患者颈动脉内膜中膜厚度与动态血压参数的关系[J].中国老年学杂志,2017,37(8):1914-1916. [6] 吴 迪,马 宁,王 芳,等.超声弹性成像评估H型高血压与颈动脉硬化斑块特点的相关性[J].中国临床医学影像杂志,2018,29(7):517-519. [7] Zhang Y，Wang G，Liu J,et al.Impact of hyperhomocysteinemia on insulin resistance in patients with H-typehypertension[J].Clin Exp Hypertens,2018,40(1):28-31. [8] 罗羽慧,梅 霞,金 平,等.马来酸依那普利叶酸片对H型高血压并发2型糖尿病患者颈动脉粥样硬化的影响及可能机制[J].中国药房,2018,29(5):670-674. [9] 肖红霞,尚晓峰,孔繁玲,等.张掖市不同民族H型高血压伴糖尿病血清Hcy、HbA1c与颈动脉硬化的关系[J].中国初级卫生保健,2018,32(9):85-87. [10] 吴 迪,马 宁,王 芳,等.H型高血压患者血清25-羟维生素D浓度与颈动脉斑块稳定性的相关性研究[J].河北医科大学学报,2018,39(11):1348-1351. [11] 苏兆萍,杨寓玲,刘长城,等.急性缺血性卒中合并颈动脉斑块患者神经功能损伤与血浆氧化低密度脂蛋白水平相关性研究[J].中国卒中杂志,2017,12(4):309-313. [12] 叶 璐,马 骥.超声造影评价H型高血压患者颈动脉斑块内新生血管的价值[J].现代实用医学,2017,29(1):1542-1544. [13] 李 凤,朱余友,杨孙凤,等.血清五聚素3、超敏C反应蛋白、脂蛋白相关磷脂酶 A2水平以及微栓子信号与大动脉粥样硬化型急性脑梗死患者颈动脉粥样硬化斑块稳定性的相关研究[J].临床神经病学杂志,2016,29(2):95-100. [14] 杨 峰,郭民旺,周汝娟,等.甲钴胺对H型高血压患者血浆炎性因子及颈动脉斑块的影响[J].中国综合临床,2015,31(1):30-32. [15] 茹建平,杨庆华,贾贤达,等.中年H型高血压患者颈动脉内中膜厚度与 Hcy、Cyst-C、UA、Lp（a）的相关性研究[J].海南医学院学报,2017,23(2):149-151.

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备注/Memo

备注/Memo:
*广西自治区钦州市科学研究与技术开发计划项目 (201714314)
更新日期/Last Update: 2019-07-12