[1]陆俊杰,张 洋,张清清,等.经微导管注射替罗非班联合Solitaire支架取栓治疗急性脑梗死21例临床研究*[J].陕西医学杂志,2019,(6):740-743.
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经微导管注射替罗非班联合Solitaire支架取栓治疗急性脑梗死21例临床研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年6期
页码:
740-743
栏目:
临床研究
出版日期:
2019-06-05

文章信息/Info

文章编号:
DOI:〖HT5K〗10.3969/j.issn.1000-7377.2019.06.016
作者:
陆俊杰张 洋张清清陈国芳郑 伟王 磊张冠群傅新民
江苏省徐州市中心医院神经内科 (徐州 221009)
关键词:
急性脑梗死Solitaire AB支架机械取栓术替罗非班
分类号:
R743.3
文献标志码:
A
摘要:
摘 要 〖HT5K〗目的:探讨经微导管注射替罗非班联合Solitaire AB支架机械取栓和(或)支架植入术等多模式血管内治疗急性大血管闭塞性脑梗死的安全性及效果。 方法:收集优先行头颈联合CTA检查,部分患者优先行头颅MRA检查,以上二者之一影像学检查提示本次急性脑梗死患者的颅内责任大血管完全闭塞,连续入选患者共计106例,并直接行急诊脑血管支架取栓术失败,术后仍存在颅内血管闭塞患者共21例,经微导管注入替罗非班行补救性血管再通治疗,包括使用球囊成形或支架植入术以开通闭塞的血管。比较补救性血管再通治疗的患者的基线资料、手术前后的脑血管造影结果、住院以及随访期间主要不良脑血管事件的发生情况,以及患者预后情况。 结果:21例患者中经补救性血管再通治疗后术后脑梗死溶栓治疗分级TICI 2b/3级18例(85.7%);患者均未发生再发脑梗死及责任血管血运重建事件;良好预后10例(47.6%);所有患者均未出现症状性颅内出血。 结论:经微导管注射小剂量替罗非班联合Solitaire AB支架机械取栓和(或)支架植入术等血管再通治疗急性脑梗死是相对安全、有效的,但应严格把握手术适应证。

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备注/Memo

备注/Memo:
*江苏省徐州市社会发展-公共卫生项目(KC16SW175)
更新日期/Last Update: 2019-06-20