[1]葛文安,王盛兴,郭 涛,等.腹腔镜肾盂成形术与传统肾盂成形术治疗小儿肾积水疗效对比研究[J].陕西医学杂志,2019,(5):584-587.
 GE Wenan,WANG Shengxing,GUO Tao,et al.Comparative analysis of the effect of laparoscopic pyeloplasty and traditional pyeloplasty in children with hydronephrosis[J].,2019,(5):584-587.
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腹腔镜肾盂成形术与传统肾盂成形术治疗小儿肾积水疗效对比研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年5期
页码:
584-587
栏目:
临床研究
出版日期:
2019-05-05

文章信息/Info

Title:
Comparative analysis of the effect of laparoscopic pyeloplasty and traditional pyeloplasty in children with hydronephrosis
文章编号:
DOI: 10.3969/j.issn.10007377.2019.05.012
作者:
葛文安王盛兴郭 涛李国栋陈 伟张高峰
西安市儿童医院泌尿外科 (西安710003)
Author(s):
GE Wen’an WANG Shengxing GUO Taoet al.
Department of Urology, Xi’an Children’s Hospital (Xi’an 710003)
关键词:
肾积水外科学腹腔镜肾盂成形术肾盂成形术对比研究儿童
Keywords:
Key words HydronephrosisSurgeryLaparoscopic pyeloplasty PyeloplastyComparative studyChild
分类号:
R726.9
文献标志码:
A
摘要:
摘 要 目的:观察腹腔镜肾盂成形术与传统肾盂成形术在小儿肾积水中的应用效果。方法:60例小儿肾积水患者随机分为对照组、观察组,对照组采用传统肾盂成形术治疗,观察组采用腹腔镜肾盂成形术治疗。比较两组手术指标、术后并发症、治疗前后肾血流动力学指标变化、血β2MG、α1MG、Scr水平变化。结果:两组手术时间、术中出血量、进食时间、住院时间比较,差异均无统计学意义(P>0.05)。两组术后尿路感染、吻合口尿漏、吻合口梗阻、肠梗阻等并发症发生率差异无统计学意义(P>0.05)。治疗后,两组肾血流动力学指标PS、ED、TAMx、TAMn均显着高于同组治疗前(P<0.05)。治疗后,观察组PS、ED、TAMx、TAMn显着高于对照组(P<0.05)。治疗后,两组血清β2MG、α1MG水平均显着低于同组治疗前(P<0.05)。治疗后,观察组血清β2MG、α1MG水平显着低于对照组(P<0.05)。结论:采用腹腔镜式肾盂成形术治疗小儿肾积水,可显著改善患儿血流动力学状态,改善肾功能。
Abstract:
Abstract Objective:To observe the application effect of laparoscopic pyeloplasty and traditional pyeloplasty in children with hydronephrosis. Methods: Sixty patients with hydronephrosis were randomly divided into control group and observation group. The control group was treated with traditional pyeloplasty. The observation group was treated with laparoscopic pyeloplasty. Surgical indexes such as operation time, hospitalization time, and intraoperative blood loss were compared between the two groups to compare the occurrence of postoperative fruit complications. The changes of renal hemodynamic parameters and blood β2MG, α1MG and Scr levels were compared before and after treatment.Results: There were no significant differences in operation time,intraoperative blood loss, eating time, and hospital stay time between the two groups (P>0.05). There was no significant difference in the incidence of postoperative urinary tract infection, anastomotic leakage, anastomotic obstruction, and intestinal obstruction between the two groups (P>0.05). After treatment, PS, ED, TAMx and TAMn were significantly higher in the two groups than before treatment (P<0.05). After treatment, the PS, ED, TAMx and TAMn in the observation group were significantly higher than the control group(P<0.05). After treatment, the serum levels of β2MG and α1MG in the two groups were significantly lower than those in the same group before treatment (P<0.05). After treatment, the levels of serum β2MG and α1MG in the observation group were significantly lower than the control group (P<0.05). Conclusion: Laparoscopic pyeloplasty for children with hydronephrosis can significantly improve the hemodynamic status of children and improve renal function, which is suitable for clinical application.

参考文献/References:

[1] 李 棚,杨美英.儿童肾积水98例个体化护理体会[J].陕西医学杂志,2016,45(9):1271. [2] Dai LN, Chen CD, Lin XK, et al. Retroperitoneal laparoscopy management for ureteral fibroepithelial polyps causing hydronephrosis in children: a report of five cases[J]. J Pediatr Urol,2015,11(5):251-257. [3] Isoyama T, Iwamoto H, Inoue S, et al. Hydronephrosis after retroperitoneal laparoscopic dismembered AndersonHynes pyeloplasty in adult patients with ureteropelvic junction obstruction: A longitudinal analysis[J]. Cent European J Urol,2014,67(1):101-105. [4] Nishi M, Iwamura M, Kurosaka S, et al. Laparoscopic AndersonHynes pyeloplasty without symphysiotomy for hydronephrosis with horseshoe kidney[J]. Asian J Endosc Surg,2013,6(3):192-196. [5] Nerli RB,Nerli RB, Reddy MN, et al. Surgical outcomes of laparoscopic dismembered pyeloplasty in children with giant hydronephrosis secondary to ureteropelvic junction obstruction[J]. J Pediatr Urol,2013,9(1):110. [6] Patil S, Goel A, Yadav R,et al. Surgical outcomes of laparoscopic dismembered pyeloplasty in children with giant hydronephrosis secondary to ureteropelvic junction obstruction[J]. J Pediatr Urol,2013,9(1):109. [7] 黄澄如,孙 宁,张潍平. 实用小儿泌尿外科学[M].北京:人民卫生出版社, 2006:213-214. [8] Barbosa JA, Kowal A, Onal B, et al. Comparative evaluation of the resolution of hydronephrosis in children who underwent open and roboticassisted laparoscopic pyeloplasty[J]. J Pediatr Urol,2013,9(2):199-205. [9] Carlstrom M. Hydronephrosis and risk of later development of hypertension[J]. Acta Paediatr,2019,108(1):50-57. [10] Zhao S, Li W, Cheng F, et al. Highpressure carbon dioxide pneumoperitoneum induces oxidative stress and mitochondriaassociated apoptotic pathway in rabbit kidneys with severe hydronephrosis[J]. Int J Mol Med,2019,43(1):305315. [11] 邵林海.组合式输尿管软镜下手术治疗感染性输尿管上段结石临床效果及对患者免疫功能、氧化应激水平的影响研究[J].陕西医学杂志,2018,47(6):767-770. [12] 陈 昆, 韩前河, 张 楠,等.复方金钱草颗粒对体外冲击波碎石术后输尿管结石疗效观察[J].陕西中医, 2017, 38(12):1668-1669. [13] Djahangirian O, Young I, Dorgalli C, et al. Safe discharge parameters for patients with isolated antenatal hydronephrosis[J]. J Pediatr Urol,2018,14(4):321. [14] Kandur Y, Salan A, Guler AG, et al. Diuretic renography in hydronephrosis: a retrospective singlecenter study[J]. Int Urol Nephrol,2018,50(7):1199-1204. [15] Hosohata K, Jin D, Takai S, et al. Vanin1 in renal pelvic urine reflects kidney injury in a rat model of hydronephrosis[J]. Int J Mol Sci,2018,19(10):3186. [16] CardonaGrau D, Bayne CE. Featuring: Comparative effectiveness of a pilot patientcentered ultrasound report in the management of hydronephrosis[J]. J Pediatr Urol,2018,14(2):186-187. [17] Freedman AL. Prenatal HydronephrosisAnother Swing of the Pendulum?[J]. J Urol,2018,200(2):256-257. [18] Zhang L, Gao M, Zhang T, et al. Surgical management of retroperitoneal schwannoma complicated with severe hydronephrosis: A case report[J]. Medicine (Baltimore),2018,97(39):e12528. [19] 苏虹霞,吕继宏.黄芪注射液联合胰岛素泵强化治疗糖尿病肾病Ⅲ期疗效研究[J].陕西中医,2018,39(4):479-481. [20] Jordan LA, Green L. Late breast cancer metastasis to the urinary bladder presenting with bilateral hydronephrosis[J]. Radiol Case Rep,2018,13(6):1238-1241.

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更新日期/Last Update: 2019-05-07