[1]唐亚荣.循环热灌注化疗联合替吉奥及热疗治疗老年胃癌癌性腹水临床研究*[J].陕西医学杂志,2019,(4):435-437，441.
　TANG Yarong..Clinical effect analysis of combined therapy with tiago and hyperthermia in the treatment of malignant ascites in elderly patients with gastric cancer[J].,2019,(4):435-437，441.
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循环热灌注化疗联合替吉奥及热疗治疗老年胃癌癌性腹水临床研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年4期
页码:
435-437，441
栏目:
临床研究
出版日期:
2019-04-05

文章信息/Info

Title:
Clinical effect analysis of combined therapy with tiago and hyperthermia in the treatment of malignant ascites in elderly patients with gastric cancer
文章编号:
DOI: 10.3969/j.issn.10007377.2019.04.007
作者:
唐亚荣
上海市金山区中西医结合医院内分泌科（上海 201501）
Author(s):
TANG Yarong.
Department of Endocrinae，Shanghai Jinshan District Chinese and Western Medicine Association Hospital (Shanghai 201501)
关键词:
胃癌; 癌性腹水; 循环热灌注化疗; 热疗; 替吉奥; 临床疗效
Keywords:
Key words Gastric cancer;  Cancerous ascites;  Circulating thermoplastic chemotherapy;  Heat treatment; Tiggio; Clinical curative effect
分类号:
R735.2
文献标志码:
A
摘要:
摘 要 目的：探究循环热灌注化疗联合替吉奥及热疗在老年胃癌癌性腹水中的临床治疗效果。方法：选取100例老年胃癌癌性腹水患者作为本次临床试验研究观察与分析对象，对照组50例患者给予循环热灌注化疗治疗，观察组50例患者给予循环热灌注化疗联合替吉奥及热疗治疗，对两组患者的临床治疗总有效率、不良反应发生率、生活质量等进行观察和对比。结果：观察组患者临床总有效率为66%，对照组患者临床总有效率为46%，差异具有统计学意义（P＜0.05）；观察组和对照组的不良反应发生率分别为20%和40%，差异具有统计学意义（P＜0.05）；观察组生活质量评分比对照组高，差异具有统计学意义（P＜0.05）。结论 ：对胃癌癌性腹水患者实施循环热灌注化疗联合替吉奥及热疗治疗，能够有效提高患者的临床疗效，改善患者的生活质量，不良反应可控，值得临床应用。
Abstract:
Abstract Objective:To explore and analyze the clinical therapeutic effect of combined cyclic thermoplastic chemotherapy with tiago and hyperthermia in the treatment of senile gastric cancer with cancerous ascites. Methods： 100 cases of elderly patients with gastric cancerous ascites as the observation and analysis of the clinical trials research object, the control group of 50 cases patients with circulating hot perfusion chemotherapy treatment, observation group of 50 cases patients with heat circulation perfusion chemotherapy combined for gonow and heat treatment, the clinical total effective rate of two groups of patients, the incidence of adverse reactions, such as the quality of life observation and comparison. Results:The total clinical efficiency was 66% in the observation group and 46% in the control group(P<0.05). The difference was statistically significant. The incidence of adverse reactions in the observation group and the control group was 20% and 40%(P<0.05), and the difference was statistically significant. The life quality score of the observation group was higher than that of the control group(P<0.05), and the difference was statistically significant. Conclusion:the combined therapy of cyclic thermoperfusion with tiago and hyperthermia can effectively improve the clinical efficacy and quality of life of patients with gastric cancer patients with ascites, and the controlled adverse reactions are worthy of clinical application.

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备注/Memo

备注/Memo:
*上海市科技计划项目（2017SF325）
更新日期/Last Update: 2019-04-10