[1]汤克虎,高峻峰,任尽平.药物涂层球囊在糖尿病患者冠状动脉小血管病变治疗中的应用研究*[J].陕西医学杂志,2019,(4):432-434.
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药物涂层球囊在糖尿病患者冠状动脉小血管病变治疗中的应用研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年4期
页码:
432-434
栏目:
临床研究
出版日期:
2019-04-05

文章信息/Info

文章编号:
DOI: 10.3969/j.issn.10007377.2019.04.006
作者:
汤克虎; 高峻峰; 任尽平
北京怀柔医院(北京101400)
关键词:
药物涂层球囊; 冠心病; 小血管病变; 糖尿病; 药物洗脱支架; 疗效
分类号:
R541.4
文献标志码:
A
摘要:
摘 要 目的: 分析药物涂层球囊（DCB）在糖尿病（DM）患者冠状动脉小血管病变应用中的疗效。方法:选取因心绞痛或其他不典型症状行冠状动脉造影检查患者65例，随机分为DCB组和DES组，比较两组靶病变最小管腔直径（MLD）、晚期管腔丢失（LLL）、主要不良心血管事件（MACE）发生率。结果:两组术后即刻MLD均较术前显著增加（P＜0.01），且DES组高于DCB组［(2.06±0.24)mm对(1.62±0.38)mm , P＜0.001］;术后9个月DCB组靶病变LLL小于DES组［(0.06±0.43)mm对(0.37±0.47)mm, P=0.02］;两组术后9个月内 MACE发生率比较，差异无统计学意义（P＞0.05）。结论:DCB可减少DM患者冠状动脉小血管病变LLL，MACE发生率与DES相似，展现出良好的应用前景。

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备注/Memo

备注/Memo:
*国家自然科学基金资助项目(20180635)
更新日期/Last Update: 2019-04-10