[1]刘 杰,陈文美,冯 成,等.程控硬膜外间歇脉冲注入技术分娩镇痛对分娩结局的影响观察*[J].陕西医学杂志,2019,(3):304-306,310.
 LIU Jie,CHEN Wenmei,FENG Cheng,et al.Effects of parturition analgesia on the outcome of labor by programmedepidural intermittent pulse injection technique[J].,2019,(3):304-306,310.
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程控硬膜外间歇脉冲注入技术分娩镇痛对分娩结局的影响观察*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年3期
页码:
304-306,310
栏目:
基础研究
出版日期:
2019-03-05

文章信息/Info

Title:
Effects of parturition analgesia on the outcome of labor by programmedepidural intermittent pulse injection technique
文章编号:
DOI:10.3969/j.issn.10007377.2019.03.006
作者:
刘 杰陈文美冯 成朱 涛方 育
上海市松江区中心医院麻醉科(上海 201600)
Author(s):
LIU JieCHEN WenmeiFENG Chenget al.
Department of Anesthesiology in Central Hospital of Shanghai Songjiang District(Shanghai 201600)
关键词:
程控硬膜外间歇脉冲注入技术硬膜外阻滞分娩镇痛分娩结局腹部手术影响
Keywords:
Key words Programmed epidural intermittent pulse injectionEpidural blockLabor anlgesiaOutcome of laborAbdominal surgeryInflences
分类号:
R614.4
文献标志码:
A
摘要:
摘 要 目的:观察程控硬膜外间歇脉冲注入(PIEB)技术分娩镇痛对分娩结局的影响。方法:采用前瞻性研究,选择拟分娩镇痛的初产妇246例,经产妇或家属知情同意后随机分为两组,均使用罗哌卡因、舒芬太尼镇痛,其中采用PIEB技术的123例为PIEB组,采用常规连续硬膜外(CEA)输注镇痛的123例为CEA组,从镇痛即刻开始,采用视觉模拟评分法(VAS)于分娩镇痛前、用药后2 h和宫口开全时评价疼痛程度,观察并分析用药总量、PCA次数、分娩方式、产后出血、胎儿窘迫及新生儿1 min、5 min Apgar评分。结果:PIEB组T1 、T2 VAS评分明显低于CEI组,PCA次数明显少于CEA组,罗哌卡因和舒芬太尼用量明显少于CEA组,差异均有统计学意义(P<0.05)。PIEB组顺产、产钳助产、剖宫产率分别为82.93%、8.94%、8.13%,CEA组分别为81.30%、9.76%、8.94%,差异无统计学意义(P>0.05)。PIEB组产后出血、胎儿窘迫发生率为3.25%、2.44%,CEA组为4.07%、3.25%,差异无统计学意义(P>0.05)。两组新生儿1 min、5 min Apgar评分差异无统计学意义(P>0.05)。结论:PIEB技术分娩镇痛与连续硬膜外输注分娩镇痛分娩结局相同,但PIEB技术可减少麻醉药物用量,提高镇痛效果。
Abstract:
Abstract Objective: To observe the effects of parturition analgesia by programmed epidural intermittent pulse injection (PIEB) on the outcome of labor. Methods: Adopt prospective study, choose labor analgesia of primipara 246 cases as the research object, through the maternal or families were randomly divided into two groups after informed consent, use ROM pp paid, sufentanil analgesia, with 123 cases using PIEB technology for PIEB group, the conventional continuous epidural infusion analgesia (CEA) in 123 cases for the CEA group, from analgesia begins immediately, by using visual analogue scale (VAS) before and after 2 h in labor analgesia palace mouth open fulltime evaluation of the degree of pain, The total dosage, number of PCA, mode of delivery, postpartum bleeding, fetal distress and neonatal 1 min and 5 min apgar score were recorded. Results: T1, T2 PIEB group, VAS score was lower than that in group CEI, PCA significantly less than the CEA group, luo pp paid and ShuFen, the dosage is obviously less than the CEA group, differences were statistically significant (P<0.05). The rates of spontaneous.delivery, forceps delivery and cesarean section delivery in PIEB group were 82.93%, 8.94% and 8.13% respectively, while those in CEA group were 81.30%, 9.76% and 8.94% respectively, and the difference was not statistically significant (P>0.05). The incidence of postpartum hemorrhage and fetal distress in PIEB group were 3.25% and 2.44%, while those in CEA group was 4.07% and 3.25%, with no statistically significant difference (P>0.05). There was no significant difference in the scores of 1 min and 5 min apgar between the two groups (P>0.05). Conclusion: PIEB technology can reduce the dosage of narcotic drugs and improve the analgesic effect.

参考文献/References:

[1] 石 磊,赵 伟,周 宇, 等.肠道支架置入术与急诊手术治疗急性梗阻性结直肠癌疗效的Meta分析[J].中国全科医学,2016,19(8):941945.
[2] 樊雪梅,周春秀,刘婧岩, 等.分娩镇痛联合自由体位分娩对初产妇分娩结局的影响[J].齐鲁护理杂志,2016,22(6):1214. \[3\] 马少平,孔丽娜,何莲芝, 等.40例分娩镇痛母婴结局分析[J].皖南医学院学报,2017,36(2):125127. \[4\] 李 莉,吕 艳,王 冰, 等.经皮神经电刺激的镇痛机制及其在分娩镇痛中的应用[J].医学综述,2018,24(6):12111216. \[5\] 〖JP2〗Chen SY,Lin PL,Yang YH,et al.The effeets of different epkdural analgesia formulas on labor and mode of delivery in nulliparous wonen [J].Obstet Gynecol,2014,53(1):811.〖JP〗
[6] George RB,Allen TK,Habib AS.Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia:a systematic review and metaanalysis[J].Anesth Analg,2013,116(1):133144.
[7] 陈祥楠,杨世辉,林辉瑞, 等.穴位注射罗哌卡因的分娩镇痛效果及其对产妇皮质醇水平的影响[J].南方医科大学学报,2018,38(4):502504.
[8] 〖JP3〗李 莉,吕 艳,翟翔隽, 等.全产程多模式分娩镇痛对母婴安全的影响[J].国际妇产科学杂志,2018,45(2):145149.〖JP〗
[9] 黄 科,欧明灵.全产程分娩镇痛与第一产程分娩镇痛对母婴结局的影响对比[J].解放军医药杂志,2018,30(1):102104. 
[10] 王志强.双管法镇痛对胎头位置异常产妇分娩结局的影响[J].中国现代医学杂志,2017,27(21):113116.
[11] 赵晓亮,陈晓芳,徐桂萍.罗哌卡因规律间断硬膜外分娩镇痛对分娩结局的影响[J].中国医师杂志,2017,19(11):17041706.
[12] 张茜茜,周雪微,董小琼.不同时机分娩镇痛对产妇母婴结局的影响[J].浙江临床医学,2017,19(1):8586.
[13] 马宏伟.非药物分娩镇痛的应用现状及研究进展[J].西部医学,2018,30(5):769772.
[14] 朱雄珊.分娩镇痛对阴道助产分娩率及母婴结局的影响[J].中国生育健康杂志,2016,27(4):372373. 
[15] 何亮亮,徐世琴,汪福州,等.规律性间断硬膜外注射用于病人自控硬膜外分娩镇痛背景给药法的效果[J].中华麻醉学杂志,2009,29(11):10501052. 
[16] 李孝红,冯善武.不同间隔时间行规律硬膜外给药复合 PCEA用于分娩镇痛的比较[J].临床麻醉学杂志,2015,31(8):773776

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备注/Memo

备注/Memo:
*国家自然科学基金资助项目 (81660456)
更新日期/Last Update: 2019-03-15