[1]宋 婷,罗 莉,贾 菲,等.1540 nm非剥脱性点阵激光联合水凝胶医用冷敷贴治疗 凹陷性痤疮瘢痕疗效研究[J].陕西医学杂志,2019,(2):241-243.
　SONG Ting,LUO Li,JIA Fei,et al.Effiicacy of nonablative 1540nm fractional laser with medical cool patch in the treatment of acne sca[J].,2019,(2):241-243.
点击复制

1540 nm非剥脱性点阵激光联合水凝胶医用冷敷贴治疗 凹陷性痤疮瘢痕疗效研究
分享到：

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年2期
页码:
241-243
栏目:
临床研究
出版日期:
2020-02-05

文章信息/Info

Title:
Effiicacy of nonablative 1540nm fractional laser with medical cool patch in the treatment of acne sca
文章编号:
DOI: 10.3969/j.issn.10007377.2019.02.028
作者:
宋 婷; 罗 莉; 贾 菲; 高 琳
空军军医大学西京皮肤医院（西安710032）
Author(s):
SONG Ting;  LUO Li; JIA Fei;  et al. 
Department of Dermatology,Xijing Hospital,The Fourth Military Medical University（Xi’an 710032）
关键词:
寻常痤疮; 瘢痕; 治疗; 激光疗法; 水凝胶医用冷敷贴; 疗效
Keywords:
Key words Acne vulgaris; Cicatrix; Therapy; Laser therapy; Medical cool patch; Therapeutic effect
分类号:
R751.05
文献标志码:
A
摘要:
摘 要 目的：评价1540 nm非剥脱性点阵激光联合水凝胶医用冷敷贴治疗凹陷性痤疮瘢痕的临床疗效。方法：80例凹陷性痤疮瘢痕患者纳入本研究，其中观察组40例、对照组40例。1540 nm非剥脱性点阵激光治疗后观察组患者应用水凝胶医用冷敷贴，对照组应用医用冰袋冷敷。分别对两组患者术后的瘢痕改善、视觉模拟评分（VAS）、疼痛持续时间、结痂时间、脱痂时间及完全愈合时间、不良反应等进行评价分析。结果：两组患者经过治疗后痤疮瘢痕均有不同程度改善，差异无统计学意义（P>0.05）。观察组患者术后VAS评分（2.48±1.15）分、疼痛持续时间（2.43±0.86）h、结痂时间（2.45±1.13）d、脱痂时间（5.20±1.01）d及完全愈合时间（8.50±1.24）d均短于对照组，差异均有统计学意义（P<0.05）。观察组患者不良反应发生率明显低于对照组（P<0.05）。结论：1540 nm非剥脱性点阵激光治疗凹陷性痤疮瘢痕后联合应用水凝胶医用冷敷贴，可以有效降低患者治疗后疼痛及灼烧感，缩短红斑持续时间及结脱痂时间，不良反应发生率低。
Abstract:
Abstract Objective：To evaluate the clinical efficacy of nonablative 1540nm fractional laser with medical cool patch in the treatment of acne scar. Methods：80 patients with acne scar were treated by nonablative 1540nm fractional laser. They were randomly divided into two groups: medical cool patch were used in observation group (n=40), ice compress were used in control group (n=40). Efficacy, pain, duration of burning, erythema duration, decrustation time, postoperative complications were analyzed. Results：Two groups were improved after treatment, there were no statistically significant difference (P0.05). In the observation group, the postoperative pain was (2.48±1.15), duration of burning was (2.43±0.86),crustation time was (2.45±1.13), decrustation time was (5.20±1.01) and healing time was (8.50±1.24), all the results were shorter than control group (P<0.05).Conclusion：The application of nonablative 1540nm fractional laser with medical cool patch in the treatment of acne scar can effectively reduce postoperative pain and burning sensation, shorten the duration of erythema and crusting time after operation. It also reduces the incidence of complications.

参考文献/References:

\[1\] 赵 辨.中国临床皮肤病学［M］．南京: 江苏科学技术出版社，2010: 1165．
\[2\] 朱学骏，顾有守，沈丽玉．实用皮肤病性病治疗学［M］.2版．北京: 北京医科大学中国协和医科大学联合出版社，1998:404．
\[3\] Lanoue J, Goldenberg G.Acne scarring: a review of cosmetic therapies［J］．Cutis,2015,95:276281．
\[4\] Hwang YJ, Lee YN, Lee YW, et al. Treatment of acne scars and wrinkles in asian patients using carbon dioxide fractional laser resurfacing: its effects on skin biophysical profiles［J］．Ann Dermatol，2013，25:445 453．
\[5\] You HJ, Kim DW, Yoon ES, et al．Comparison of four different lasers for acne scars: Ｒesurfacing and fractional lasers［J］．J Plast Reconstr Aesthet Surg,2016,69:e87e95．
\[6\] Marqa MF, Mordon S. Laser fractional photothermolysis of the skin: numerical simulation of microthermal zones［J］．J Cosmet Laser Ther，2014, 16:5765．
\[7\] 袁艳丽.脉冲CO2点阵激光联合E光治疗面部凹陷性瘢痕43例临床观察\[J\]. 陕西医学杂志，2017，46（1）:9294.
\[8\] 尉煜青,张学光,李 萍.火针治疗痤疮的研究进展\[J\].陕西中医,2016,37(9):12671269.
\[9\] 曾永芳,鲁元刚,杨宏珍,等. 二氧化碳点阵激光联合硅酮凝胶治疗面部痤疮瘢痕疗效分析\[J\].中国医疗美容, 2014,4(2):6768.〖ZK)〗
\[10\] 刘艳华，杨慧兰，陈胡林，等. 脉冲CO2点阵激光治疗痤疮瘢痕不良反应及并发症分析［J］．中国美容医学，2013，22(1):8486.
\[11\] 郭 健，朴海燕．水凝胶敷料及其促进伤口愈合的特点\[J\]．国外医学：护理学分册，2004，23(11):518519．
\[12\] Winter GD．Formation of the scab and the rate of epithelisation of superficial wounds in the skin of the young domestic pig\[J\]．J Wound Care,1995,4(8)：366371．
\[13\] 许晶晶，庄 燕.水胶体敷料预防注射尼莫地平所致静脉炎的效果观察\[J\]．中外医学研究,2012,10(25):125．

相似文献/References:

[1]刘 宾,陶 谏△,崔 鑫,等.封闭式负压治疗对改善美容缝合伤口愈合质量的临床研究*[J].陕西医学杂志,2019,(11):1522.
　LIU Bin,TAO Jian,CUI Xin,et al.Clinical study of closed negative pressure treatment on improving the healing quality of cosmetic suture wounds[J].,2019,(2):1522.

更新日期/Last Update: 2019-03-13