[1]孙红艳,王改华.不同手术方式治疗卵巢癌临床效果及对患者生育功能的影响[J].陕西医学杂志,2019,(2):213-216.
　SUN Hongyan,WANG Gaihua..Clinical effects of different surgical treatments on 125 patients with ovarian  cancer and their influence on reproductive function[J].,2019,(2):213-216.
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不同手术方式治疗卵巢癌临床效果及对患者生育功能的影响
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年2期
页码:
213-216
栏目:
临床研究
出版日期:
2020-02-05

文章信息/Info

Title:
Clinical effects of different surgical treatments on 125 patients with ovarian  cancer and their influence on reproductive function
文章编号:
DOI: 10.3969/j.issn.10007377.2019.02.020
作者:
孙红艳; 王改华
西安市第四医院妇产科（西安710004）
Author(s):
SUN Hongyan; WANG Gaihua.
Department of Obstetrics and Gynecology,Xi’an No.4 Hospital (Xi’an 710004)
关键词:
上皮性卵巢癌; 单侧附件切除术; 月经; 复发; 生育功能; 临床效果 
Keywords:
Key words Epithelial ovarian cancer;  Unilateral adnexectomy;  Menstruation; Recurrence; Fertility function;  Clinical effect
分类号:
R737.31
文献标志码:
A
摘要:
摘 要 目的:探讨不同手术方式治疗卵巢癌患者的临床效果及对生育功能的影响。方法：125例早期上皮性卵巢癌患者，术前根据病理情况及家属意愿选择手术，手术方式主要包括以下三种：①单侧附件切除术；②单/双侧卵巢肿物剥除术；③单/双侧卵巢肿物剥除同时给予分期手术。记录患者手术分组情况，术后随访及复发情况；比较不同手术方式患者术后月经情况及妊娠情况。结果：125例患者中，行单侧附件切除术者53例，单/双侧卵巢肿物剥除术者39例，单/双侧卵巢肿物剥除同时给予分期手术者33例，所有患者术后均给予化疗治疗。术后随访2年，复发9例，均为单/双侧卵巢肿物剥除术者。所有患者术后均月经回潮，术后1年内月经正常者96例（76.80%）；月经无规律者29例（23.20%）。不同手术方式患者术后月经情况存在统计学差异（χ2=9.403，P=0.009）。单侧附件切除组与单/双侧卵巢肿物剥除+分期手术组比较，单侧附件切除组月经正常者45例（84.91%），明显高于单/双侧卵巢肿物剥除+分期手术组的57.58%（χ2=7.979，P=0.005）。术后成功受孕者52例，妊娠成功率41.60%；未受孕者73例（58.40%）。不同手术方式患者术后妊娠情况存在统计学差异（χ2=44.600，P=0.000）。三组患者术后妊娠情况两两比较，均存在统计学差异（χ2=42.619，P=0.000；χ2=13.539，P=0.000；χ2=9.611，P=0.002）。结论: 单侧附件切除术临床效果良好，可有效保留患者生育功能，值得推广应用。
Abstract:
Abstract Objective：This study aim to investigate the clinical effect of different surgical methods on ovarian cancer and their influence on reproductive function. Methods：125 patients with early epithelial ovarian cancer admitted were selected and operated on according to their pathological conditions and family members' wishes. The operation methods mainly included three kinds:①unilateral adnexal excision；②unilateral/bilateral ovarian tumor dissection；③ unilateral/bilateral ovarian tumor dissection and staged surgery. The situation of the surgical group, followedup and recurrence were recorded, and the menstrual status and pregnancy status were compared among different surgical groups. Results: Among 125 patients, 53 underwent unilateral adnexal excision, 39 underwent unilateral/bilateral ovarian tumor dissection, and 33 underwent unilateral/bilateral ovarian tumor dissection and staged surgery. All patients received chemotherapy after operation. After 2 years of followup, 9 cases recurred which all of them were single or bilateral ovariectomy. All patients had menstrual regurgitation. 96 (76.80%) had normal menstruation and 29 (23.20%) had irregular menstruation within 1 year after operation. The menstrual condition of patients with different surgical methods had statistical difference (χ2=9.403, P=0.009). 45 cases (84.91%) had normal menstruation in unilateral adnexal removal group, which was significantly higher than that of 57.58% in unilateral/bilateral ovarian tumor dissection and staged surgery group (χ2=7.979, P=0.005). Successful pregnancy was achieved in 52 cases with the pregnancy success rate of 41.60%, and 73 cases (58.40%) were not pregnant. There was statistical difference in pregnancy after operation (χ2=44.600, P=0.000). There were statistical differences among the three groups when compared with any group in the postoperative pregnancy （χ2=42.619，P=0.000；χ2=13.539，P=0.000；χ2=9.611，P=0.002）。Conclusion: Unilateral adnexal excision has a good clinical effect, and it can effectively preserve the fertility of patients. It is worth popularizing and applying.

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更新日期/Last Update: 2019-03-13