[1]姚超峰,李会广△.不规则抗体检测及IgG抗-A(B)血型抗体效价在多次妊娠史孕妇产前检查中的临床价值[J].陕西医学杂志,2018,(11):1507-1509.
　Yao Chaofeng,Li Huiguang..Clinical value of irregular antibody detection and IgG anti-A (B) blood type antibody titer in prenatal examination of multiple pregnancy history[J].,2018,(11):1507-1509.
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不规则抗体检测及IgG抗-A(B)血型抗体效价在多次妊娠史孕妇产前检查中的临床价值
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2018年11期
页码:
1507-1509
栏目:
临床检验
出版日期:
2018-11-29

文章信息/Info

Title:
Clinical value of irregular antibody detection and IgG anti-A (B) blood type antibody titer in prenatal examination of multiple pregnancy history
文章编号:
0.3969/j.issn.1000-7377.2018.11.042
作者:
姚超峰1; 李会广2△
1.陕西省核工业215医院输血科(咸阳 712000)，2.陕西省铜川矿务局中心医院核医学科（铜川727000）
Author(s):
Yao Chaofeng; Li Huiguang.
Department of Transfusion, 215 Hospital, Xianyang Nuclear Industry (Xianyang 712000)
关键词:
妊娠;  多胎产前保健@血型抗体效价@不规则抗体检测
Keywords:
Pregnancy;  multiplePrenatal care@Blood group antibody titer@Irregular antibody test
分类号:
R714.14
文献标志码:
A
摘要:
目的：探究在多次妊娠史孕妇产前检查中不规则抗体及IgG抗-A(B)血型抗体效价检测的临床价值。方法：选取进行孕期检查的450例孕妇作为研究对象，所有孕妇均进行不规则抗体检测，同时检测O型孕妇产前IgG抗-A(B)血型抗体效价。比较初次妊娠孕妇与多次妊娠史孕妇产前不规则抗体检测阳性情况及IgG抗-A(B)血型抗体效价阳性检出率。结果：多次妊娠孕妇不规则抗体阳性率（5.38%）明显高于初次妊娠孕妇不规则抗体阳性率（1.05%），其差异具有统计学意义（χ2=6.008，P=0.014）；多次妊娠孕妇IgG抗-A(B)血型抗体效价阳性发生率（71.43%）明显高于初次妊娠孕妇IgG抗-A(B)血型抗体效价阳性发生率（48.48%），其差异具有统计学意义（χ2=8.204，P=0.004）。结论：在多次妊娠史孕妇产前检查中不规则抗体及IgG抗-A(B)血型抗体效价检测具有重要的临床价值，能够早期诊断和干预新生儿溶血病，实现优生优育。
Abstract:
Objective：To explore the clinical value of irregular antibody detection and IgG anti-Ab blood group antibody titer in prenatal examination of pregnant women with multiple pregnancy history.Methods：450 pregnant women who were examined during pregnancy in our hospital were selected as the subjects of this study. All pregnant women were tested for irregular antibodies. At the same time, the titer of IgG blood group antibody of O type pregnant women before delivery was detected. The positive rate of irregular antibody detection and IgG anti Ab before pregnancy were compared between the first pregnant women and the pregnant women with multiple pregnancy history. The titer of blood group antibody was positive.Results：The positive rate of irregular antibody (5.38 %) in pregnant women with multiple pregnancies was significantly higher than that of irregular antibody in pregnant women (1.05 %) . The difference was statistically significant (χ2=6.008，P=0.014).The positive rate ( 71.43 % ) of IgG anti-A (B) blood type antibody in pregnant women with multiple pregnancies was significantly higher than that of IgG anti-A (B) blood type antibody (48.48%) in primary pregnant women.The difference was statistically significant（χ2=8.204,P=0.004）.Conclusion：In prenatal examination of pregnant women with multiple pregnancy history, the detection of irregular antibody and IgG anti-Ab blood group antibody titer has important clinical value, it can early diagnose and interfere with neonatal hemolytic disease, and realize eugenic and excellent birth.

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更新日期/Last Update: 2018-11-30