[1]王瑞,刘亚利.晚期肺癌炎症指数在肺癌中的预后价值和临床应用展望[J].陕西医学杂志,2026,(7):1001-1004.[doi:DOI:10.3969/j.issn.1000-7377.2026.07.023]
　WANG Rui,LIU Yali.Prognostic value and clinical application prospects of advanced lung cancer inflammation index in lung cancer[J].,2026,(7):1001-1004.[doi:DOI:10.3969/j.issn.1000-7377.2026.07.023]
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晚期肺癌炎症指数在肺癌中的预后价值和临床应用展望

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2026年7期
页码:
1001-1004
栏目:
综述
出版日期:
2026-07-05

文章信息/Info

Title:
Prognostic value and clinical application prospects of advanced lung cancer inflammation index in lung cancer
作者:
王瑞1; 刘亚利2
（1.空军军医大学第二附属医院全科医学科，陕西 西安 710038；2.空军军医大学第二附属医院肿瘤科，陕西 西安710038）
Author(s):
WANG Rui1; LIU Yali2
(1.Department of General Practice,the Second Affiliated Hospital of Air Force Military Medical University,Xi’an 710038,China；2.Department of Oncology,the Second Affiliated Hospital of Air Force Military Medical University,Xi’an 710038,China)
关键词:
晚期肺癌炎症指数; 肺癌; 炎症指数; 营养状态; 临床价值
Keywords:
Advanced lung cancer inflammation index; Lung cancer; Inflammation index; Nutritional status; Clinical value
分类号:
R 734.2
DOI:
DOI:10.3969/j.issn.1000-7377.2026.07.023
文献标志码:
A
摘要:
晚期肺癌炎症指数（ALI）是一种综合反映炎症状态与营养状况的复合指标，研究表明，低ALI与晚期肺癌患者较差的总生存期、无进展生存期、治疗反应及术后并发症风险显著相关。ALI在预测预后方面优于单一炎症指标，并在晚期肺癌患者中展现出广泛适用性。然而，其临床应用仍面临标准化不足、截断值不统一等挑战。未来研究应聚焦于ALI的动态监测、生物学机制及其与新型治疗方法的结合，以推动个体化治疗。
Abstract:
The advanced lung cancer inflammation index (ALI) is a composite biomarker that reflects both systemic inflammatory status and nutritional condition.Studies have shown that a low ALI is significantly associated with poorer overall survival,progression-free survival,diminished therapeutic response,and increased risk of postoperative complications in patients with advanced lung cancer.ALI outperforms single inflammatory indicators in predicting prognosis and demonstrates wide applicability in patients with advanced lung cancer.However,its clinical implementation faces challenges such as lack of standardization and inconsistent cutoff values.Future research should prioritize dynamic ALI monitoring,elucidate its underlying biological mechanisms,and explore its integration with novel therapeutic strategies to advance personalized medicine.

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备注/Memo

备注/Memo:
国家自然科学基金资助项目（82172587）
更新日期/Last Update: 2026-07-10