[1]胡燕,苗燕,陈津津,等.急性大脑中动脉狭窄脑梗死磁共振检查T2-FLAIR高信号血管征对患者神经功能及预后的影响[J].陕西医学杂志,2025,54(7):939-943.[doi:DOI:10.3969/j.issn.1000-7377.2025.07.013]
　HU Yan,MIAO Yan,CHEN Jinjin,et al.Effect of T2-FLAIR hypersignal vascular sign in acute middle cerebral artery stenosis on neurological function and prognosis in cerebral infarction[J].,2025,54(7):939-943.[doi:DOI:10.3969/j.issn.1000-7377.2025.07.013]
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急性大脑中动脉狭窄脑梗死磁共振检查T2-FLAIR高信号血管征对患者神经功能及预后的影响

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
54
期数:
2025年7期
页码:
939-943
栏目:
临床研究
出版日期:
2025-07-05

文章信息/Info

Title:
Effect of T2-FLAIR hypersignal vascular sign in acute middle cerebral artery stenosis on neurological function and prognosis in cerebral infarction
作者:
胡燕; 苗燕; 陈津津; 叶民; 刚书成
（南京明基医院，江苏 南京 210019）
Author(s):
HU Yan; MIAO Yan; CHEN Jinjin; YE Min; GANG Shucheng
（Nanjing Mingji Hospital，Nanjing 210019，China）
关键词:
磁共振; T2液体衰减反转恢复序列; 高信号血管征; 急性大脑中动脉狭窄脑梗死; 神经功能缺损; 预后
Keywords:
Magnetic resonance imaging; T2 liquid decay reversal recovery sequence; High signal vascular sign; Acute middle cerebral artery stenosis and cerebral infarction; Neurological dysfunction; Prognosis
分类号:
R 743
DOI:
DOI:10.3969/j.issn.1000-7377.2025.07.013
文献标志码:
A
摘要:
目的：探讨磁共振（MRI）-T2液体衰减反转恢复序列（FLAIR）高信号血管征（HVS）与急性大脑中动脉狭窄脑梗死患者神经功能缺损情况及预后的关系。方法：选取急性大脑中动脉狭窄脑梗死患者134例，均给予MRI-T2 FLAIR检查，分析HVS发生情况，比较发生和未发生HVS患者临床资料差异，以及发生HVS的不同特征患者间HVS评分差异，分析HVS特征预测急性大脑中动脉狭窄脑梗死患者预后的价值。结果：共有72例患者有HVS，HVS发生率为53.73%。HVS阳性患者美国国立卫生研究院卒中量表（NIHSS）评分、脑梗死体积分别为9（4，12）分和17.22（13.50，21.40）cm3，低于HVS阴性患者（均P＜0.05）；HVS阳性患者血管狭窄程度高于HVS阴性患者（P＜0.05），其重度狭窄和完全闭塞比例达到90.28%；HVS阳性患者预后不良比例为30.56%，低于HVS阴性患者（均P＜0.05）。HVS阳性患者中，NIHSS评分≥9分患者HVS评分为3.10（2，4）分，低于NIHSS评分＜9分患者（P＜0.05），预后不良患者HVS评分为2.20（1，3）分，低于预后良好患者（P＜0.05）。HVS评分与NIHSS评分呈负相关（r=－0.661，P＜0.05），与mRS评分呈正相关（r=0.541，P＜0.05）。HVS特征预测急性大脑中动脉狭窄脑梗死患者预后良好的ROC曲线下面积为0.627（95%CI：0.531～0.724，P＜0.05）。在HVS阳性患者中，HVS评分预测预后良好的ROC曲线下面积为0.847（95%CI：0.755～0.940，P＜0.05）。结论：与 HVS阴性患者比较，HVS阳性患者预后不良比例低，神经功能受损情况更轻，HVS评分在预后预测中的应用价值较好。
Abstract:
Objective:To explore the relationship between high signal vascular sign(HVS) of magnetic resonance imaging(MRI)-T2 fluid attenuated inversion recovery sequence(FLAIR) and neurological dysfunction and prognosis in patients with acute middle cerebral artery stenosis and cerebral infarction.Methods：134 patients with acute middle cerebral artery stenosis and cerebral infarction treated in our hospital from January 2022 to February 2024 were selected，all of whom underwent MRI-T2 FLAIR high examination.The occurrence of HVS was analyzed，and the differences in clinical data between patients with and without HVS were compared，as well as the differences in HVS scores among patients with different characteristics of HVS.Results:A total of 72 patients had HVS，the incidence rate was 53.73%.The National Institutes of Health Stroke Scale(NIHSS) score and cerebral infarction volume of patients with HVS positive were 9(4，12) points and 17.22(13.50，21.40)cm3，respectively，which were lower than those of patients with HVS negative(all P＜0.05).The degree of vascular stenosis in patients with HVS positive was higher than that in patients with HVS negative(P＜0.05)，and the proportion of severe stenosis and complete occlusion reached 90.28%.The proportion of patients with HVS positive with poor prognosis was 30.56%，which was lower than that of patients with HVS negative(all P＜0.05).Among patients with HVS，those with NIHSS scores≥9 had HVS scores of 3.10(2，4)，which were lower than those with NIHSS scores＜9(P＜0.05).Patients with poor prognosis had HVS scores of 2.20(1，3)，which were lower than those with good prognosis(P＜0.05).The HVS score was negatively correlated with the NIHSS score(r=-0.661，P＜0.05) and positively correlated with the mRS score(r=0.541，P＜0.05).The area under the ROC curve for predicting good prognosis in patients with acute middle cerebral artery stenosis and cerebral infarction using HVS features was 0.627(95%CI：0.531~0.724)，with P＜0.05.In patients with HVS positive，the area under the ROC curve predicted by HVS score for good prognosis was 0.847(95%CI：0.755~0.940)，with P＜0.05.Conclusion:Compared with HVS-negative patients，HVS-positive patients have a low proportion of poor prognosis and less severe neurological impairment，and the application value of HVS score in prognosis prediction is better.

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备注/Memo

备注/Memo:
江苏省科学技术基金资助项目（2021241）；南京市医学科技发展项目（ZKX21061）
更新日期/Last Update: 2025-07-07