[1]王 韵,彭代辉.迷走神经刺激治疗难治性抑郁研究进展[J].陕西医学杂志,2025,54(4):575-封3.[doi:DOI:10.3969/j.issn.1000-7377.2025.04.028]
　WANG Yun,PENG Daihui.Research Progress on Vagus Nerve Stimulation Therapy for Refractory Depression[J].,2025,54(4):575-封3.[doi:DOI:10.3969/j.issn.1000-7377.2025.04.028]
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迷走神经刺激治疗难治性抑郁研究进展
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
54
期数:
2025年4期
页码:
575-封3
栏目:
综 述
出版日期:
2025-04-05

文章信息/Info

Title:
Research Progress on Vagus Nerve Stimulation Therapy for Refractory Depression
作者:
王 韵; 彭代辉
(上海市精神卫生中心心境障碍科,上海 200060)
Author(s):
WANG Yun; PENG Daihui
(Department of Mood Disorders,Shanghai Mental Health Center,Shanghai 200060,China)
关键词:
难治性抑郁症;  迷走神经刺激;  神经调节;  疗效
Keywords:
Treatment refractory depression;  Vagus nerve stimulation;  Neural regulation;  Therapeutic effect
分类号:
R 749.42
DOI:
DOI:10.3969/j.issn.1000-7377.2025.04.028
文献标志码:
A
摘要:
难治性抑郁症(TRD)是一种难以治疗的抑郁症类型,通常对抗抑郁药物和心理治疗无效。近年来,迷走神经刺激(VNS)作为一种新的神经调节技术逐渐成为治疗TRD的一种备选方案。本文通过系统综述现有文献探讨迷走神经刺激在TRD治疗中的应用现状、机制及其疗效,并分析其临床局限性与未来研究方向。
Abstract:
Treatment Refractory Depression(TRD)is a type of depression that is difficult to treat and often ineffective with antidepressants and psychotherapy.In recent years,vagus nerve stimulation(VNS)has gradually become an alternative treatment for TRD as a new neuroregulatory technique.This article systematically reviews existing literature to explore the current application status,mechanism,and efficacy of vagus nerve stimulation in the treatment of TRD,and analyzes its clinical limitations and future research directions.

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备注/Memo

备注/Memo:
[基金项目]上海市精神卫生中心“卓越教师培养计划”(2023-ZY-04); 上海交通大学“交大之星”计划医工交叉研究基金资助项目(YG2022QN107)
更新日期/Last Update: 2025-04-07