[1]熊 欢,蒋丹丹,陈 涛,等.窄带成像技术联合放大内镜在胃上皮内瘤变及早期胃癌中的应用价值[J].陕西医学杂志,2024,(11):1517-1520.[doi:DOI:10.3969/j.issn.1000-7377.2024.11.017]
　XIONG Huan,JIANG Dandan,CHEN Tao,et al.Application value of narrow band imaging combined with magnifying endoscopy in gastric intraepithelial neoplasia and early gastric cancer[J].,2024,(11):1517-1520.[doi:DOI:10.3969/j.issn.1000-7377.2024.11.017]
点击复制

窄带成像技术联合放大内镜在胃上皮内瘤变及早期胃癌中的应用价值
分享到：

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2024年11期
页码:
1517-1520
栏目:
临床研究
出版日期:
2024-11-05

文章信息/Info

Title:
Application value of narrow band imaging combined with magnifying endoscopy in gastric intraepithelial neoplasia and early gastric cancer
作者:
熊 欢; 蒋丹丹; 陈 涛; 余 杨; 荆晓娟
(遂宁市中心医院消化内镜中心,四川 遂宁 629000)
Author(s):
XIONG Huan; JIANG Dandan; CHEN Tao; YU Yang; JING Xiaojuan
(Department of Digestive Endoscopy Center,Suining Central Hospital,Suining 629000,China)
关键词:
早期胃癌;  胃上皮内瘤变;  窄带成像技术;  放大内镜;  应用价值
Keywords:
Early gastric cancer;  Gastric intraepithelial neoplasia;  Narrow band imaging;  Magnifying endoscopy;  Application value
分类号:
R 735.2
DOI:
DOI:10.3969/j.issn.1000-7377.2024.11.017
文献标志码:
A
摘要:
目的:探讨窄带成像技术(NBI)联合放大内镜(ME)在胃上皮内瘤变及早期胃癌(EGC)中的应用价值。方法:选取就诊的疑似胃上皮内瘤变及EGC患者108例为研究对象,均接受常规白光内镜检查与NBI-ME检查。比较常规白光内镜与NBI-ME的图像质量评分。以组织病理学结果为金标准,比较白光内镜和NBI-ME诊断胃上皮内瘤变及EGC的准确率。比较胃上皮内瘤变及EGC在NBI-ME下的特征。结果:NBI-ME在病灶轮廓、胃黏膜表层形态、微血管形态方面的图像质量评分均高于常规白光内镜(均P<0.05)。组织病理学检查结果,胃上皮内瘤变60例, EGC48例。白光内镜诊断胃上皮内瘤变46例,EGC 35例,其诊断胃上皮内瘤变准确率为76.67%,诊断EGC准确率为72.92%。NBI-ME诊断胃上皮内瘤变56例,EGC 44例,其诊断胃上皮内瘤变准确率为93.33%,诊断EGC准确率为91.67%。NBI-ME诊断胃上皮内瘤变及EGC的准确率高于白光内镜(均P<0.05)。胃上皮内瘤变与EGC在边界线、不规则表面微结构和黏膜微血管、腺管密度、黏膜微血管密度方面比较差异有统计学意义(均P<0.05)。结论:NBI-ME在胃上皮内瘤变和EGC的诊断中具有较高的应用价值。
Abstract:
Objective:To investigate the application value of narrow band imaging(NBI)combined with magnifying endoscopy(ME)in gastric intraepithelial neoplasia and early gastric cancer(EGC).Methods:A total of 108 patients suspected of gastric intraepithelial neoplasia and EGC were selected.All of them underwent white light endoscopy and NBI-ME.Image quality of conventional white light endoscopy and NBI-ME was compared.With histopathologic results as the gold standard,the accuracy rates of white light endoscopy and NBI-ME in diagnosing gastric intraepithelial neoplasia and EGC were compared.The characteristics of gastric intraepithelial neoplasia and EGC under NBI-ME were compared.Results:Image quality scores of NBI-ME were higher than those of conventional white light endoscopy in terms of lesion contour,gastric mucosal surface morphology,and microvascular morphology(all P<0.05).Histopathologic results showed 60 cases with gastric intraepithelial neoplasia and 48 cases with EGC.White light endoscopy diagnosed 46 cases with gastric intraepithelial neoplasia and 35 cases with EGC.The diagnostic accuracy rates for gastric intraepithelial neoplasia and EGC were 76.67% and 72.92%,respectively.NBI-ME diagnosed 56 cases with gastric intraepithelial neoplasia and 44 cases with EGC.The diagnostic accuracy rates for gastric intraepithelial neoplasia and EGC were 93.33% and 91.67%,respectively.The accuracy rates of NBI-ME in diagnosing gastric intraepithelial neoplasia and EGC were higher than those of white light endoscopy(all P<0.05).There were significant differences between gastric intraepithelial neoplasia and EGC in terms of boundary line,irregular surface microstructure,irregular mucosal microvessels,glandular duct density,and mucosal microvessel density(all P<0.05).Conclusion:NBI-ME has relatively high application value in the diagnosis of gastric intraepithelial neoplasia and EGC.

参考文献/References:

[1] 布力布?吉力斯汉,赛福丁?柯尤木,刘春晖,等.长链非编码RNA核富集转录子1对胃癌SGC7901细胞迁移、侵袭、自噬的影响及机制研究[J].陕西医学杂志,2023,52(12):1749-1753.
[2] 沈家林,许雨晴,曹若彤,等.金果胃康胶囊对胃癌前病变模型大鼠胃黏膜ULK1/AMPK/mTOR信号通路的影响[J].陕西中医,2024,45(4):446-450.
[3] 颜玲玲,吴坚芬,顾彬彬,等.血小板与淋巴细胞比值和中性粒细胞与淋巴细胞比值对早期胃癌诊断的预测价值[J].中华消化杂志,2022,42(3):163-170.
[4] GUO X,PENG Y,SONG Q,et al.A liquid biopsy signature for the early detection of gastric cancer in patients[J].Gastroenterology,2023,165(2):402-413.
[5] 华科雷,霍明科,董志闯,等.外周血小板淋巴细胞比值变化在新辅助化疗胃癌患者预后中的价值[J].中华医学杂志,2022,102(12):858-863.
[6] 李伟峰,王警,李士杰,等.普通和放大及超声内镜对未分化型早期胃癌的诊断价值[J].中华肿瘤防治杂志,2023,30(18):1110-1115.
[7] 魏晓华,郭俊霞.不同内镜技术在食管癌及癌前病变筛查中的应用价值研究[J].陕西医学杂志,2019,48(5):591-594.
[8] 徐林生.NBI内镜与常规白光内镜对早期胃癌的诊断价值比较[J].现代消化及介入诊疗,2019,24(12):1468-1470.
[9] YAO K,ANAGNOSTOPOULOS G K,RAGUNATH K.Magnifying endoscopy for diagnosing and delineating early gastric cancer[J].Endoscopy,2009,41(5):462-467.
[10] DIXON M F.Gastrointestinal epithelial neoplasia:Vienna revisited[J].Gut,2002,51(1):130-131.
[11] 郑蓓怡,李之印,叶月芳.胃蛋白酶原及胃泌素-17对筛查胃癌及胃上皮内瘤变的价值[J].中国实用内科杂志,2021,41(6):545-549.
[12] 安敏,高振军.白光内镜联合超声内镜检查术在早期胃癌诊断中的应用价值[J].中国内镜杂志,2023,29(7):67-72.
[13] YOUNG E,PHILPOTT H,SINGH R.Endoscopic diagnosis and treatment of gastric dysplasia and early cancer:Current evidence and what the future may hold[J].World J Gastroenterol,2021,27(31):5126-5151.
[14] 金蕊,何卫才,郭甲民,等.培元化瘀解毒方联合新辅助化疗治疗胃癌临床观察[J].陕西中医,2023,44(9):1227-1230.
[15] 张金宝,史琦玉,周杨,等.双焦距与放大胃镜联合窄带成像技术对早期胃癌诊断的比较研究[J].中华肿瘤防治杂志,2021,28(5):356-359,390.
[16] 赵慧金,尔丽绵,李晓明,等.普通白光联合窄带成像放大内镜对早期胃癌浸润深度的诊断价值[J].中国肿瘤临床,2022,49(19):994-1000.
[17] 陈弟,蒋逍达,何鑫琦,等.基于深度学习的放大蓝激光成像和放大窄带成像模式下早期胃癌识别模型的诊断效果对比[J].中华消化杂志,2021,41(9):606-612.
[18] KAWADA K,ARIMA M,MIYAHARA R,et al.Effect of adding magnifying BLI,magnifying NBI,and iodine staining to white light imaging in diagnosis of early esophageal cancer[J].Endosc Int Open,2021,9(12):e1877-e1885.
[19] 李雪,邢洁,张倩,等.窄带成像技术联合放大内镜JES分型对早期食管癌的诊断价值[J].首都医科大学学报,2022,43(2):210-215.
[20] 林波,粟兴,黄虹玉,等.普通白光内镜、超声内镜及放大内镜结合窄带显像在早期胃癌内镜治疗适应症中的临床价值[J].四川大学学报(医学版),2022,53(1):154-159.
[21] 常风娟,马俊宝,胡鸿涛.NBI放大内镜联合Survivin、Cry61检测与老年结直肠癌疾病诊断及预后的关系[J].中国老年学杂志,2021,41(8):1611-1614.
[22] KURUMI H,NONAKA K,IKEBUCHI Y,et al.Fundamentals,diagnostic capabilities and perspective of narrow band imaging for early gastric cancer[J].J Clin Med,2021,10(13):2918.
[23] 谢德金,王小忠,孙晓丹,等.窄带成像技术结合放大内镜在早期胃癌诊断中的应用价值[J].中国医师杂志,2019,21(1):46-49.
[24] 赵亮,冯璐璐,王笑楠.放大内镜和内镜窄带光成像下胃癌病变的特点及与病理分型的关系[J].中国肿瘤临床与康复,2022,29(1):55-59.
[25] 吴义娟,陈现亮,周胜云,等.白光内镜、放大内镜及放大内镜联合窄带成像技术对早期胃癌的诊疗价值[J].实用心脑肺血管病杂志,2021,29(6):110-116.

相似文献/References:

[1]王卫卫,邢文韬,张爱青,等.血管内皮生长因子、程序性死亡受体-1联合胃功能三项对早期胃癌的诊断及预后评估价值[J].陕西医学杂志,2024,(12):1663.[doi:DOI:10.3969/j.issn.1000-7377.2024.12.015]
　WANG Weiwei,XING Wentao,ZHANG Aiqing,et al.Value of VEGF,PD-1 combined with gastric function in diagnosis and prognosis evaluation of early gastric cancer[J].,2024,(11):1663.[doi:DOI:10.3969/j.issn.1000-7377.2024.12.015]

备注/Memo

备注/Memo:
基金项目:消化道早癌医师共同成长计划科研立项课题(GTCZ-2020-SC-51-0001)
更新日期/Last Update: 2024-11-04