[1]杨旭虎,徐 伍,刘建成,等.易栓症分子遗传学研究进展[J].陕西医学杂志,2023,52(10):1442-1445.[doi:DOI:10.3969/j.issn.1000-7377.2023.10.037]
 YANG Xuhu,XU Wu,LIU Jiancheng,et al.Research progress on molecular genetics of thrombophilia[J].,2023,52(10):1442-1445.[doi:DOI:10.3969/j.issn.1000-7377.2023.10.037]
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易栓症分子遗传学研究进展
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
52
期数:
2023年10期
页码:
1442-1445
栏目:
综 述
出版日期:
2023-10-05

文章信息/Info

Title:
Research progress on molecular genetics of thrombophilia
作者:
杨旭虎1徐 伍2刘建成3杨海霞4马 鑫3李玉洁1范 进1裴海峰5
(1.西部战区总医院神经内科,四川 成都 610083; 2.南方医科大学第五附属医院泌尿外科,广东 广州510900; 3.西部战区总医院康复科,四川 成都 610083; 4.西部战区总医院儿科,四川 成都 610083; 5.西部战区总医院心内科,四川 成都 610083)
Author(s):
YANG XuhuXU WuLIU JianchengYANG HaixiaMA XinLI YujieFAN JinPEI Haifen
(Department of Neurology,General Hospital of the Western Theater Command,Chengdu 610083,China)
关键词:
易栓症 分子遗传学 基因 种族 地域 血栓筛查
Keywords:
Thrombophilia Molecular genetics Gene Race Territory Thrombosis screening
分类号:
R 394.3
DOI:
DOI:10.3969/j.issn.1000-7377.2023.10.037
文献标志码:
A
摘要:
易栓症是多种遗传或获得性因素导致的容易发生血栓栓塞的疾病或状态,严重影响人们的身体健康。随着分子遗传学方法开始应用于遗传性易栓症相关基因的染色体定位,逐步发现了与其易感性有关的数种基因。现就易栓症相关基因的染色体定位、遗传易感基因及其与种族、地域的关系等作一综述,以期为相关人群易栓症的防治提供参考。
Abstract:
Thrombophilia is a disease or state that is prone to thromboembolism caused by a variety of genetic or acquired factors,which seriously affects people's health.With the application of molecular genetic methods to the chromosome mapping of genes related to hereditary thromboembolism,several genes related to its susceptibility have been gradually discovered.This article reviews the chromosome location of thrombophilia related genes,genetic susceptibility genes and their relationship with race and region,with a view to providing reference for the prevention and treatment of thrombophilia in related populations.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81970241); 西部战区总医院院管重点项目(2021-XZYG-A03)
更新日期/Last Update: 2023-10-07