[1]陈 晔,周玉玲,张 念.Damon Q自锁托槽正畸治疗疗效及对患者龈沟液氧化应激指标、细胞因子水平的影响[J].陕西医学杂志,2023,52(8):1001-1005.[doi:DOI:10.3969/j.issn.1000-7377.2023.08.013]
　CHEN Ye,ZHOU Yuling,ZHANG Nian.Curative effect of Damon Q self-locking bracket orthodontic treatment and its effect on oxidative stress indexes and cytokine levels of gingival sulcus liquid[J].,2023,52(8):1001-1005.[doi:DOI:10.3969/j.issn.1000-7377.2023.08.013]
点击复制

Damon Q自锁托槽正畸治疗疗效及对患者龈沟液氧化应激指标、细胞因子水平的影响
分享到：

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
52
期数:
2023年8期
页码:
1001-1005
栏目:
临床研究
出版日期:
2023-08-05

文章信息/Info

Title:
Curative effect of Damon Q self-locking bracket orthodontic treatment and its effect on oxidative stress indexes and cytokine levels of gingival sulcus liquid
作者:
陈 晔; 周玉玲; 张 念
(清华大学玉泉医院口腔科,北京100049)
Author(s):
CHEN Ye; ZHOU Yuling; ZHANG Nian
(Department of Stomatology,Yuquan Hospital,Tsinghua University,Beijing 100049,China)
关键词:
Damon Q自锁托槽;  正畸治疗;  疗效;  牙周健康指数;  氧化应激指标;  细胞因子
Keywords:
Damon Q self-locking bracket;  Orthodontic treatment;  Curative effect;  Periodontal health index;  Oxidative stress index;  Cytokine
分类号:
R 783.5
DOI:
DOI:10.3969/j.issn.1000-7377.2023.08.013
文献标志码:
A
摘要:
目的:探讨Damon Q自锁托槽正畸治疗疗效及对患者龈沟液氧化应激指标、细胞因子水平的影响。方法:选择接受正畸治疗患者78例为研究对象,按随机数字表法分为结扎托槽组(39例,给予常规结扎式托槽矫治器)和自锁托槽组(39例,给予Damon Q自锁托槽矫治器),统计两组治疗1年后疗效,对比两组治疗前及治疗6个月后的牙周健康指数、龈沟液氧化应激指标、细胞因子水平。结果:治疗1年后,自锁托槽组有效率高于结扎托槽组(P<0.05)。治疗前,两组软垢指数(DI)、牙石指数(CI)、龈沟出血指数(SBI)、牙龈指数(GI)水平比较,差异无统计学意义(均P>0.05); 治疗1年后,两组DI、CI、SBI、GI水平均较治疗前升高,与结扎托槽组相比,自锁托槽组DI、CI、SBI、GI水平更低,差异有统计学意义(均P<0.05)。治疗前,两组超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GXH-Px)、丙二醛(MDA)水平比较,差异无统计学意义(均P>0.05); 治疗1年后,两组SOD、GXH-Px水平均较治疗前升高,MDA水平降低,与结扎托槽组相比,自锁托槽组SOD、GXH-Px水平更高,MDA水平更低,差异有统计学意义(均P<0.05)。治疗前,两组细胞间黏附分子1(CAM1)、基质金属蛋白酶-2(MMP2)、白介素-1β(IL-1β)、一氧化氮(NO)水平比较,差异无统计学意义(均P>0.05); 治疗1年后,两组CAM1、MMP2、NO、IL-1β水平均较治疗前升高,与结扎托槽组相比,自锁托槽组CAM1、MMP2、NO、IL-1β水平较低,差异有统计学意义(均P<0.05)。结论:Damon Q自锁托槽在正畸治疗中疗效显著,能够有效调节龈沟液氧化应激指标,更好地维持口腔卫生,保护牙周组织,对 CAM1、MMP2、NO、IL-1β水平影响更小,更有利于牙齿健康。
Abstract:
Objective:To investigate the curative effect of Damon Q self-locking bracket orthodontic treatment and its effect on oxidative stress indexes and cytokine levels of gingival sulcus liquid.Methods:Seventy-eight patients receiving orthodontic treatment were selected as the study objects and divided into the ligation bracket group(39 patients receiving conventional ligation bracket appliance)and the self-locking bracket group(39 patients receiving Damon Q self-locking bracket appliance)according to the random number table method.The curative effect of the two groups after 1 year of treatment was analyzed.The periodontal health index,oxidative stress index and cytokine levels of gingival sulcus liquid were compared between the two groups before treatment and 6 months after treatment.Results:After 1 year of treatment,the effective rate of self-locking bracket group was higher than that of ligation bracket group(P<0.05).Before treatment,there were no significant differences in DI,CI,SBI and GI between the two groups(all P>0.05).After 1 year of treatment,the levels of DI,CI,SBI and GI in two groups were higher than those before treatment,and the levels of DI,CI,SBI and GI in the self-locking bracket group were lower than those in the ligation bracket group(all P<0.05).Before treatment,there were no significant differences in the levels of SOD,GXH-Px and MDA between the two groups(all P>0.05).After 1 year of treatment,SOD and GXH-Px levels in both groups were higher than those before treatment,while MDA level was lower; compared with the ligation bracket group,SOD and GXH-Px levels in the self-locking bracket group were higher and MDA level was lower(all P<0.05).Before treatment,there were no significant differences in the levels of CAM1,MMP2,IL-1β and NO between the two groups(all P>0.05).After 1 year of treatment,the levels of CAM1,MMP2,NO and IL-1β in two groups were higher than those before treatment,and the levels of CAM1,MMP2,NO and IL-1β in the self-locking bracket group were lower than those in the ligation bracket group(all P<0.05).Conclusion:Damon Q self-locking bracket is effective in orthodontic treatment,which can effectively regulate the oxidative stress indexes of gingival sulcus liquid,better maintain oral hygiene,protect periodontal tissues,and have less effect on the levels of CAM1,MMP2,NO and IL-1β,which is more conducive to dental health.

参考文献/References:

[1] Robertson L,Kaur H,Fagundes NCF,et al.Effectiveness of clear aligner therapy for orthodontic treatment:A systematicreview[J].Orthod Craniofac Res,2020,23(2):133-142.
[2] 李湘琳,崔强强,梁文慧,等.SanderⅢ矫治器矫治早期骨性Ⅲ类错牙合疗效分析[J].陕西医学杂志,2017,46(2):226-228.
[3] 管丽敏,逯 宜,鲍庆红,等.龈下残根正畸修复联合治疗的临床研究[J].陕西医学杂志,2017,46(2):224-225,228.
[4] 陈 功,顾梦婕,殷薇薇,等.Damon Q自锁托槽联合上颌斜面导板或玻璃离子垫用于非拔牙矫治安氏Ⅱ类2分类错牙合的效果[J].安徽医学,2022,43(12):1438-1442.
[5] 王 茜,屈振宇,韩 冰.Damon Q自锁托槽和传统结扎式托槽对非拔牙矫治牙列拥挤的疗效比较[J].临床口腔医学杂志,2021,37(8):494-498.
[6] 俞立英,朱亚琴,邹德荣,等.口腔医学[M].上海:复旦大学出版社,2014:337-367.
[7] 郜 罕,王慧敏.无托槽隐形矫治器与固定矫治器对正畸治疗患者龈沟液可溶性细胞间黏附分子-1、白介素-1β、基质金属蛋白酶-8及超氧化物歧化酶、谷胱甘肽过氧化物酶水平的影响[J].陕西医学杂志,2021,50(11):1408-1411,1419.
[8] Zheng J,Yang K.Clinical research:Low-level laser therapy in acceleratingorthodontic tooth movement[J].BMC Oral Health,2021,21(1):324.
[9] Keim RG,Graham JW,Palomo JM,et al.Obstructive sleep apneatreatment in orthodontic practices[J].J Clin Orthod,2022,56(1):23-33.
[10] Mota JSL,Azevedo DGR,Campos MJD,et al.Orthodontictreatment after intrusive dislocation and fracture of the maxillary centralincisors[J].Am J Orthod Dentofacial Orthop,2021,160(5):757-763.
[11] 齐 娟,李淑芳.无托槽隐形矫治器与Damon Q自锁托槽对拔牙病例牙弓形态影响的临床研究[J].临床口腔医学杂志,2022,38(9):549-552.
[12] 宋欣羽,钱玉芬.利用ABO-OGS指数评价Damon Q自锁托槽与MBT托槽矫治效果研究[J].中国实用口腔科杂志,2021,14(5):560-564.
[13] Chen J,Wen J,Huang L,et al.Comparisons of maxillaryincisor retraction effects for patients with first premolar extractions between Damon Q and invisalign:A retrospective study[J].Medicine(Baltimore),2022,101(40):30919.
[14] Zhu YC,Zhu FJ,Zhai L,et al.Effect of invisible appliance withoutbracket and self-locking bracket appliance on periodontal and subgingival florain patients with periodontitis[J].Shanghai Kou Qiang Yi Xue,2022,31(2):184-188.
[15] Svh V,Pudi S,Gade RR,et al.Assessment of salivary malondialdehyde and superoxide dismutase levels in completely edentulous patients:An in vivo study[J].Cureus,2022,14(8):27949.
[16] Menéndez LC,Menendez ML,Aguilar-Salvatierra A,et al.Salivary markers of oxidative stress in patients undergoing orthodontic treatment with clearaligners versus self-ligating brackets:A non-randomized clinical trial[J].J ClinMed,2022,11(12):3531.
[17] Chitra P,Prashantha GS,Rao A.Investigation of gingivalhealth and oxidative stress changes in patients undergoing orthodontic treatmentwith and without fluoride use[J].J Indian Soc Periodontol,2022,26(2):123-129.
[18] 孙丽艳,邹桂克.微型种植体支抗正畸对成人安氏Ⅱ类1分类错牙合畸形患者牙齿咬合力及龈沟液MMP2、NO水平的影响[J].中国医疗美容,2020,10(2):64-67.
[19] 李 晋.加味葛根芩连汤联合根面平整术治疗慢性牙周炎临床研究[J].陕西中医,2022,43(7):914-917.
[20] 邹 晖,李朝晖,左园林,等.不同矫治力对口腔正畸患者龈沟液IL-1β、TIMP-2、MMP-2、Cathepsin K表达的影响[J].广东医学,2022,43(7):908-912.
[21] 刘 宁,邓少山.微型种植体支抗在口腔正畸治疗中的应用价值[J].海南医学院学报,2015,21(6):859-861,864.

相似文献/References:

[1]刘沼汛,张军梅,郑之峻.成年人正畸治疗与颧、颊、颞部软组织变化研究进展[J].陕西医学杂志,2024,(2):274.[doi:DOI:10.3969/j.issn.1000-7377.2024.02.028]

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(82205266); 北京登峰计划项目(DFL20181501)
更新日期/Last Update: 2023-08-07