[1]孟璠璐,刘 瑜,程 轩,等.小细胞肺癌药物治疗研究进展[J].陕西医学杂志,2022,51(10):1313-1317.[doi:DOI:10.3969/j.issn.1000-7377.2022.10.034]
 MENG Fanlu,LIU Yu,CHENG Xuan,et al.New advances in drug therapy for small cell lung cancer[J].,2022,51(10):1313-1317.[doi:DOI:10.3969/j.issn.1000-7377.2022.10.034]
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小细胞肺癌药物治疗研究进展
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
51
期数:
2022年10期
页码:
1313-1317
栏目:
综 述
出版日期:
2022-10-05

文章信息/Info

Title:
New advances in drug therapy for small cell lung cancer
作者:
孟璠璐1刘 瑜2程 轩1姚俊涛2
(1.西安医学院,陕西 西安 710021; 2.西安交通大学附属陕西省肿瘤医院,陕西 西安710061)
Author(s):
MENG FanluLIU YuCHENG XuanYAO Juntao
(Xi'an Medical University,Xi'an 710021,China)
关键词:
小细胞肺癌 化疗 聚腺苷二磷酸核糖多聚酶抑制剂 抗血管生成 免疫治疗 分子分型
Keywords:
Small cell lung cancer Chemotherapy Poly ADP-ribose polymeras inhibitor Anti-angiogenesis Immunotherapy Molecular typing
分类号:
R 734.2
DOI:
DOI:10.3969/j.issn.1000-7377.2022.10.034
文献标志码:
A
摘要:
小细胞肺癌(SCLC)作为一种神经内分泌肿瘤,具有分化程度低、侵袭性高、转移早等特点。尽管初期对放疗和化疗敏感,但大部分患者易在短时间内复发及耐药,5年生存率极低。现阶段,传统化疗药物尚未在小细胞肺癌中取得突破性进展,免疫药物等的出现则打破了小细胞肺癌治疗领域的僵局,联合治疗或能为小细胞肺癌患者带来新的希望,为临床治疗提供更多选择。
Abstract:
As a neuroendocrine tumor,small cell lung cancer(SCLC)is characterised by low differentiation,high aggressiveness and early metastasis.Despite its initial sensitivity to chemotherapy and radiotherapy,almost all patients will subsequently relapse and resistance,and the 5-year survival rate remains dismal.At present,traditional chemotherapy has made no significant progresses in small cell lung cancer.The emergence of new treatments such as immunotherapy has broken the deadlock of SCLC.Combination therapy may bring new hope to patients with small cell lung cancer and provide more choices for clinical treatment.

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备注/Memo

备注/Memo:
基金项目:陕西省中医药管理局中医药科研项目(LCPT037)
更新日期/Last Update: 2022-10-07