[1]戚新春,朱 洁.超声检查与SPECT/CT显像在分化型甲状腺癌术后残留甲状腺组织诊断中的应用价值比较[J].陕西医学杂志,2022,51(6):709-712.[doi:DOI:10.3969/j.issn.1000-7377.2022.06.016]
　QI Xinchun,ZHU Jie.Comparison of diagnostic value of ultrasonography and SPECT/CT imaging in residual thyroid tissue after differentiated thyroid cancer surgery[J].,2022,51(6):709-712.[doi:DOI:10.3969/j.issn.1000-7377.2022.06.016]
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超声检查与SPECT/CT显像在分化型甲状腺癌术后残留甲状腺组织诊断中的应用价值比较
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
51
期数:
2022年6期
页码:
709-712
栏目:
临床研究
出版日期:
2022-06-05

文章信息/Info

Title:
Comparison of diagnostic value of ultrasonography and SPECT/CT imaging in residual thyroid tissue after differentiated thyroid cancer surgery
作者:
戚新春1; 朱 洁2
(1.陕西省肿瘤医院头颈肿瘤科,陕西 西安 710061; 2.延安大学附属医院CT诊断科,陕西 延安 716099)
Author(s):
QI Xinchun; ZHU Jie
(Department of Head and Neck Oncology,Shaanxi Provincial Cancer Hospital,Xi'an 710061,China)
关键词:
超声检查;  SPECT/CT显像;  分化型甲状腺癌;  残留甲状腺组织;  促甲状腺激素;  甲状腺球蛋白
Keywords:
Ultrasonography;  SPECT/CT imaging;  Differentiated thyroid cancer;  Residual thyroid tissue;  Thyroid stimulating hormone;  Thyroglobulin
分类号:
R 736.1
DOI:
DOI:10.3969/j.issn.1000-7377.2022.06.016
文献标志码:
A
摘要:
目的:比较超声检查与SPECT/CT显像在分化型甲状腺癌(DTC)术后残留甲状腺组织诊断中的应用价值。方法:选择完成手术治疗的DTC患者82例为研究对象。记录所有患者131I剂量与血清促甲状腺激素(TSH)、甲状腺球蛋白(Tg)水平。术后6个月进行超声检查与SPECT/CT显像,判断术后残留甲状腺组织情况。结果:在82例患者中,术后发生残留甲状腺组织12例(残留组),发生率为14.6%,未发生残留甲状腺组织70例(非残留组)。残留组131I剂量及血清TSH、Tg水平高于非残留组(均P<0.05)。SPECT/CT显像诊断术后残留甲状腺组织的准确率高于超声检查(P<0.05)。ROC曲线分析显示,超声与SPECT/CT显像诊断DTC术后残留甲状腺组织的曲线下面积分别为0.635和0.899,约登指数分别为0.625和0.833。结论:相对于超声检查,SPECT/CT显像对DTC术后残留甲状腺组织的诊断价值更高,能及时发现残留部位。
Abstract:
Objective:To compare the value of ultrasonography and SPECT/CT imaging in the diagnosis of residual thyroid tissue after differentiated thyroid carcinoma(DTC)surgery.Methods: A total of 82 patients with DTC who completed the surgical treatment were selected as the study subjects.The dose of 131I and the levels of serum thyroid stimulating hormone(TSH)and thyroglobulin(Tg)were recorded in patients.Ultrasonography and SPECT/CT imaging were performed 6 months after operation to determine the residual thyroid tissue.Results:Of the 82 patients,12 had residual thyroid tissue(residual group),with an incidence rate of 14.6%,and 70 had no residual thyroid tissue(non-residual group).The 131I dose,serum TSH and Tg levels in the residual group were higher than those in the non-residual group(all P<0.05).The accuracy of SPECT/CT imaging in the diagnosis of postoperative residual thyroid tissue was higher than that of ultrasonography(P<0.05).ROC curve analysis showed that the area under the curve of residual thyroid tissue after DTC diagnosis by ultrasonography and SPECT/CT imaging was 0.635 and 0.899 respectively,and the Youden index was 0.625 and 0.833 respectively.Conclusion:Compared with ultrasonography,SPECT/CT imaging has higher diagnostic value for residual thyroid tissue after DTC surgery,and can find the residual site in time.

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备注/Memo

备注/Memo:
基金项目:陕西省重点研发计划项目(2021SF-011)
更新日期/Last Update: 2022-06-06