[1]徐 珂,高 勇.胸腔镜下疝环针带线法治疗新生儿先天性膈疝疗效观察[J].陕西医学杂志,2022,51(6):697-701.[doi:DOI:10.3969/j.issn.1000-7377.2022.06.013]
 XU Ke,GAO Yong.Therapeutic effect of thoracoscopic hernia ring needle and thread method in treatment of neonatal congenital diaphragmatic hernia[J].,2022,51(6):697-701.[doi:DOI:10.3969/j.issn.1000-7377.2022.06.013]
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胸腔镜下疝环针带线法治疗新生儿先天性膈疝疗效观察
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
51
期数:
2022年6期
页码:
697-701
栏目:
临床研究
出版日期:
2022-06-05

文章信息/Info

Title:
Therapeutic effect of thoracoscopic hernia ring needle and thread method in treatment of neonatal congenital diaphragmatic hernia
作者:
徐 珂高 勇
(宝鸡市妇幼保健院小儿外科,陕西 宝鸡 721099)
Author(s):
XU KeGAO Yong
(Department of Pediatric Surgery,Maternal and Child Health Hospital of Baoji City,Baoji 721099,China)
关键词:
新生儿先天性膈疝 胸腔镜下疝环针带线法 胸腔镜下膈肌修补术 疗效 对比研究
Keywords:
Neonatal congenital diaphragmatic hernia Thoracoscopic hernia ring needle and thread method Thoracoscopic diaphragm repair Therapeutic effect Comparative Study
分类号:
R 726.5
DOI:
DOI:10.3969/j.issn.1000-7377.2022.06.013
文献标志码:
A
摘要:
目的:观察胸腔镜下疝环针带线法治疗新生儿先天性膈疝的疗效。方法:筛选接受胸腔镜手术治疗的先天性膈疝新生儿54例为研究对象,按随机数字表法分为研究组(27例,采用胸腔镜下疝环针带线法治疗)和对照组(27例,采用胸腔镜下膈肌修补术治疗)。比较两组患儿临床疗效、围手术期指标(术中出血量、切口长度、手术时间、术后进食时间、术后机械通气时间及住院时间)、血气指标[二氧化碳分压(PaCO2)、呼气末CO2分压(ETCO2)及气道峰压]、术后并发症、复发及生存情况。结果:研究组临床总有效率高于对照组,但差异无统计学意义(P>0.05)。研究组术中出血量、切口长度、手术时间、术后进食时间、术后机械通气时间及住院时间低于对照组(均P<0.05)。两组术前、气胸后10 min及放气后30 min的ETCO2、PaCO2及气道峰压比较差异无统计学意义(均P>0.05)。气胸后10 min,两组ETCO2、PaCO2及气道峰压均明显高于术前(均P<0.05)。放气后30 min,两组ETCO2、PaCO2及气道峰压明显低于气胸后10 min(均P<0.05),但与术前比较差异无统计学意义(均P>0.05)。两组患儿术后并发症总发生率、复发率及生存率比较差异无统计学意义(均P>0.05)。结论:虽然与胸腔镜下膈肌修补术相比疗效、血气指标、并发症、复发及生存情况相当,但胸腔镜下疝环针带线法术中出血量较少,手术切口较小,手术时间、术后进食时间、术后机械通气时间及住院时间较短,在临床中治疗新生儿先天性膈疝时,若胸腔镜下疝环针带线法技术成熟,可优先选择。
Abstract:
Objective:To observe the therapeutic effect of thoracoscopic hernia ring needle and thread method in treatment of neonatal congenital diaphragmatic hernia.Methods:A total of 54 neonates with congenital diaphragmatic hernia treated by thoracoscopic surgery were selected and divided into study group(27 cases,treated with thoracoscopic hernia ring needle and thread method)and control group(27 cases,treated with thoracoscopic diaphragm repair)according to random number table method.The clinical efficacy,perioperative indexes(intraoperative blood loss,incision length,operation time,postoperative feeding time,postoperative mechanical ventilation time and hospital stay),blood gas indexes(PaCO2,ETCO2 and peak airway pressure),postoperative complications,recurrence and survival were compared between the two groups.Results:The clinical total effective rate of the study group was higher than that of the control group,but the difference was not statistically significant(P>0.05).The intraoperative blood loss,incision length,operation time,postoperative feeding time,postoperative mechanical ventilation time and hospital stay in the study group were lower than those in the control group(all P<0.05).There was no significant difference in ETCO2,PaCO2 and airway peak pressure between the two groups before operation,10 minutes after pneumothorax and 30 minutes after deflation(all P>0.05).At 10 minutes after pneumothorax,ETCO2,PaCO2 and peak airway pressure in both groups were significantly higher than those before operation(all P<0.05).At 30 minutes after deflation,ETCO2,PaCO2 and peak airway pressure in the two groups were significantly lower than those at 10 minutes after pneumothorax(all P<0.05),but there was no significant difference in comparison with preoperative(all P>0.05).There was no significant difference in the overall incidence of postoperative complications,recurrence rate and survival rate between the two groups(all P>0.05).Conclusion:Although the efficacy,blood gas indexes,complications,recurrence and survival are comparable to those of thoracoscopic diaphragmatic repair,but the intraoperative blood loss,incision length,operation time,postoperative feeding time,postoperative mechanical ventilation time and hospital stay are shorter in thoracoscopic hernia ring needle and thread method.In the clinical treatment of neonatal congenital diaphragmatic hernia,if the technique of thoracoscopic hernia ring needle and thread method is mature,it can be preferred.

参考文献/References:

[1] Kosiński P,Wielgos M.Congenital diaphragmatic hernia:Pathogenesis,prenatal diagnosis and management-literature review[J].Ginekol Pol,2017,88(1):24-30.
[2] Dingeldein M.Congenital diaphragmatic hernia:Management & outcomes[J].Adv Pediatr,2018,65(1):241-247.
[3] 马立霜,李景娜,于斯淼,等.胸腔镜手术治疗新生儿先天性膈疝[J].中华小儿外科杂志,2020,41(1):23-28.
[4] 赵生亮,潘征夏,李勇刚,等.胸腔镜和传统开放性手术治疗婴幼儿先天性膈膨升的回顾性队列研究[J].中国胸心血管外科临床杂志,2021,28(6):709-713.
[5] 熊晓峰,鲁 巍,邢福中,等.胸腔镜下疝环针带线两孔法治疗新生儿胸腹裂孔疝[J].中华小儿外科杂志,2019,40(7):598-602.
[6] Ameis D,Khoshgoo N,Keijzer R.Abnormal lung development in congenital diaphragmatic hernia[J].Semin Pediatr Surg,2017,26(3):123-128.
[7] 郑 菊,谢红宁,李丽娟,等.胎儿先天性膈疝及其相关异常的产前诊断[J].中华围产医学杂志,2010,13(2):98-101.
[8] 莫 靓,韦 兵,贺大璞,等.胸腔镜下改良膈肌折叠术治疗膈肌膨升症2例体会[J].中国内镜杂志,2019,25(2):85-88.
[9] 中华医学会小儿外科学分会内镜外科学组,中华医学会小儿外科学分会心胸外科学组.先天性膈疝修补术专家共识及腔镜手术操作指南(2017版)[J].中华小儿外科杂志,2018,39(1):1-8.
[10] 马丽霜,李 龙.腔镜手术与开放手术治疗新生儿膈疝的对比研究[J].中华小儿外科杂志,2014,35(8):599-602.
[11] 张中喜,邹加良,张清池,等.全胸腔镜手术治疗小儿先天性肺气道畸形[J].中华实用儿科临床杂志,2021,36(11):840-843.
[12] 马立霜,李景娜,于斯淼,等.胸腔镜手术治疗新生儿先天性膈疝[J].中华小儿外科杂志,2020,41(1):23-28.
[13] Costerus S,Vlot J,Rosmalen J,et al.Effects of neonatalthoracoscopic surgery on tissue oxygenation:A pilot study on(neuro-)monitoring and outcomes[J].Eur J Pediatr Surg,2019,29(2):166-172.
[14] Criss CN,Coughlin MA,Matusko N,et al.Outcomes for thoracoscopicversus open repair of small to moderate congenital diaphragmatic hernias[J].J Pediatr Surg,2018,53(4):635-639.
[15] Tyson AF,Sola RJ,Arnold MR,et al.Thoracoscopic versusopen congenital diaphragmatic hernia repair:Single tertiary center review[J].J Laparoendosc Adv Surg Tech A,2017,27(11):1209-1216.
[16] Wong M,Reyes J,Lapidus-Krol E,et al.Pulmonary hypertension in congenital diaphragmatic hernia patients:Prognostic markers and long-term outcomes[J].J Pediatr Surg,2018,53(5):918-924.
[17] Patel N,Lally PA,Kipfmueller F,et al.Ventricular dysfunction is a critical determinant of mortality incongenital diaphragmatic hernia[J].Am J Respir Crit Care Med,2019,200(12):1522-1530.
[18] 薛 锋,廖和和,王鹏国,等.胸腔镜辅助下膈疝修补术临床研究[J].陕西医学杂志,2018,47(2):199-201,205.
[19] Barroso C,Correia-Pinto J.Thoracoscopic repair of congenital diaphragmatichernia:Review of the results[J].Minerva Pediatr,2018,70(3):281-288.
[20] 周晓波,刘 佳,赵成鹏,等.胸腔镜膈疝修补术和传统开放性手术在新生儿先天性膈疝中的对比研究[J].中国现代医学杂志,2017,27(16):117-121.

备注/Memo

备注/Memo:
基金项目:陕西省重点研发计划项目(2017SF-220)
更新日期/Last Update: 2022-06-06