[1]闫琼琼,王小玲.子痫前期孕产妇并发深静脉血栓危险评估及影响因素分析[J].陕西医学杂志,2021,50(10):1231-1234.[doi:DOI:10.3969/j.issn.1000-7377.2021.10.013]
　YAN Qiongqiong,WANG Xiaoling.Risk assessment and influencing factors of deep vein thrombosis in pregnant women with preeclampsia[J].,2021,50(10):1231-1234.[doi:DOI:10.3969/j.issn.1000-7377.2021.10.013]
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子痫前期孕产妇并发深静脉血栓危险评估及影响因素分析
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
50
期数:
2021年10期
页码:
1231-1234
栏目:
临床研究
出版日期:
2021-10-05

文章信息/Info

Title:
Risk assessment and influencing factors of deep vein thrombosis in pregnant women with preeclampsia
作者:
闫琼琼1; 王小玲2
(1.西安市中心医院妇产科,陕西 西安710004; 2.陕西省地质矿产勘查开发局职工医院妇产科,陕西 西安 710014)
Author(s):
YAN Qiongqiong; WANG Xiaoling
(Department of Obstetrics and Gynecology,Xi'an Central Hospital,Xi'an 710004,China)
关键词:
妊娠;  子痫前期;  血栓;  深静脉;  危险评估;  影响因素
Keywords:
Pregnancy;  Preeclampsia;  Thrombosis;  Hazard assessment;  Influence factor
分类号:
R 714.2
DOI:
DOI:10.3969/j.issn.1000-7377.2021.10.013
文献标志码:
A
摘要:
目的:探究子痫前期孕产妇并发深静脉血栓(DVT)的危险评估和影响因素。方法:回顾性分析孕检生产的1206例并发子痫前期的患者临床资料。依据是否并发DVT,将纳入患者分为对照组(未发生DVT)和病例组(发生DVT)。Caprini风险评估法评估纳入者DVT风险。受试者工作特征(ROC)曲线分析Caprini风险评估法预测并发子痫前期患者DVT发生风险; 单因素和二元Logistic回归分析法分析影响并发子痫前期患者DVT发生的危险因素。结果:纳入患者Caprini风险评估结果中低危占比0.25%,中危20.23%,高危59.87%,极高危19.73%,其中病例组DVT发生极高危占比(72.22%)显著高于对照组(18.86%)(P<0.01)。ROC曲线分析显示,Caprini风险评估法预测并发子痫前期患者DVT发生的曲线下面积为0.815(95%CI:0.703～0.928),评分≥5分时预测患者DVT发生的灵敏度为72.2%,特异度为81.2%。单因素和Logistic回归分析显示,年龄≥35岁、体重指数(BMI)≥24 kg/m2、Caprini风险评分≥5分是影响并发子痫前期患者DVT发生的独立危险因素(均P<0.05)。结论:并发子痫前期孕产妇DVT发生风险较高,Caprini风险评估法同样适用于该类患者,对该类患者DVT发生风险具有良好预测价值。高龄妊娠、超重、Caprini风险评分≥5分等均是影响并发子痫前期孕产妇DVT发生的独立危险因素,临床应重点关注。
Abstract:
Objective:To explore the risk assessment and influencing factors of deep vein thrombosis(DVT)in pregnant women with preeclampsia.Methods:The clinical data of 1206 patients with preeclampsia during pregnancy examination were retrospectively analyzed.According to whether DVT was complicated,the included patients were divided into control group(without DVT)and case group(with DVT).Caprini risk assessment method was also used to assess the risk of DVT in the enrollees.Receiver operating characteristic(ROC)curve was used to analyze the Caprini risk assessment method to predict the risk of DVT in patients with concurrent preeclampsia.Univariate and binary Logistic regression analysis were used to analyze the risk factors that affected the occurrence of DVT.Results:In the Caprini risk assessment results of the included patients,the low-risk accounted for 0.25%,the intermediate-risk 20.23%,the high-risk 59.87%,and the extremely high-risk 19.73%.Among them,the proportion of patients with extremely high-risk of DVT in the case group(72.22%)was significantly higher than that in the control group(18.86%)(P<0.01).ROC curve analysis showed that the area under the curve of the Caprini risk assessment method for predicting the occurrence of DVT in patients with preeclampsia was 0.815(95%CI:0.703-0.928),when the score was ≥5,the sensitivity of predicting the occurrence of DVT in patients was 72.2%,and the specificity was 81.2%.Logistic regression analysis showed that age ≥ 35 years,BMI ≥ 24 kg/m2,and Caprini risk score ≥ 5 were independent risk factors affecting the occurrence of DVT in patients with concurrent preeclampsia(all P<0.05).Conclusion:The risk of DVT in pregnant women with preeclampsia is relatively high.The Caprini risk assessment method is also applicable to this type of patients,and has a good predictive value for the risk of DVT in this type of patients.Older pregnancy,overweight,Caprini risk score ≥ 5 are all independent risk factors that affect the occurrence of DVT in pregnant women with preeclampsia.For such patients,clinical attention should be given to them.

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备注/Memo

备注/Memo:
基金项目:陕西省科学技术委员会科研计划项目(16411620100)
更新日期/Last Update: 2021-10-08