[1]万育辰,王化宁,吕辉珍,等.氨磺必利对精神分裂症伴抑郁患者正负性情绪、应对方式的影响[J].陕西医学杂志,2021,50(9):1131-1134.[doi:DOI:10.3969/j.issn.1000-7377.2021.09.022]
　WAN Yuchen,WANG Huaning,LYU Huizhen,et al.Effect of amsulapride on positive and negative emotions and coping styles in schizophrenic patients with depression[J].,2021,50(9):1131-1134.[doi:DOI:10.3969/j.issn.1000-7377.2021.09.022]
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氨磺必利对精神分裂症伴抑郁患者正负性情绪、应对方式的影响
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
50
期数:
2021年9期
页码:
1131-1134
栏目:
药物与临床
出版日期:
2021-09-05

文章信息/Info

Title:
Effect of amsulapride on positive and negative emotions and coping styles in schizophrenic patients with depression
作者:
万育辰1; 王化宁2; 吕辉珍1; 张瑞国1; 冯 静3
(1.西北大学附属医院 西安市第三医院精神心理科,陕西 西安 710021; 2.空军军医大学西京医院心身科,陕西 西安710032; 3.西安电子科技大学医院,陕西 西安710071)
Author(s):
WAN Yuchen; WANG Huaning; LYU Huizhen; ZHANG Ruiguo; FENG Jing
(Department of Psychiatry,Affiliated Hospital of Northwest University,Xi'an 710021,China)
关键词:
精神分裂症;  抑郁;  氨磺必利;  正性情绪;  负性情绪;  应对方式
Keywords:
Schizophrenia;  Depression;  Amisulpride;  Positive emotion;  Negative emotion;  Coping style
分类号:
R 749.3
DOI:
DOI:10.3969/j.issn.1000-7377.2021.09.022
文献标志码:
A
摘要:
目的:探究氨磺必利对精神分裂症伴抑郁患者正负性情绪及应对方式的影响。方法:招募精神分裂症伴抑郁患者60例作为研究组,予以氨磺必利治疗4周。另选取健康志愿者20例作为对照组。比较两组治疗前正负性情绪量表(PANAS)及特质应对方式问卷(TCSQ)评分。比较研究组治疗前后简明精神病评定量表(BPRS)、PANAS、TCSQ及贝克抑郁自评量表(BDI)评分。结果:治疗前,研究组正性情绪、积极应对方式评分低于对照组,而负性情绪、负性应对方式评分高于对照组(均P<0.05)。治疗后,患者BPRS及BDI评分降低(均P<0.05); 正性情绪评分和积极应对方式评分明显高于治疗前(均P<0.05),负性情绪评分和消极应对方式评分与治疗前比较无统计学差异(均P>0.05)。结论:氨磺必利可改善精神分裂症伴抑郁患者精神症状及部分抑郁症状,负性情绪、消极应对方式可能是患者经药物治疗后社会功能恢复欠佳的重要因素。
Abstract:
Objective:To explore the effect of amsulapride on positive and negative emotions and coping styles in patients with schizophrenia and depression.Methods:Sixty patients with schizophrenia and depression were recruited as the study group and treated with amisulpride for 4 weeks.In addition,20 healthy volunteers were selected as the control group.The scores of PANAS and TCSQ before treatment were compared between the two groups.The scores of BPRS,PANAS,TCSQ,and BDI of the study group before and after treatment were compared.Results:Before treatment,the positive emotion and positive coping style scores of the study group were lower than those of the control group,while the negative emotion and negative coping style scores were higher than those of the control group(all P<0.05).After treatment,the BPRS and BDI scores of the study group decreased(all P<0.05); the positive emotion score and positive coping style score were significantly higher than those before treatment(all P<0.05),the negative emotion score and negative coping style score were not different from those before treatment(all P>0.05).Conclusion:Amisulpride can improve the psychiatric symptoms and some depressive symptoms of patients with schizophrenia and depression.Negative emotions and negative coping styles may be important factors for the poor recovery of social function of patients after drug treatment.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81974215)
更新日期/Last Update: 2021-09-06