[1]贺 煜,常莉莉,潘治军.SPECT/CT联合血清游离前列腺特异性抗原/总前列腺特异性抗原检查对前列腺癌及骨转移的诊断价值[J].陕西医学杂志,2021,50(9):1102-1105.[doi:DOI:10.3969/j.issn.1000-7377.2021.09.015]
　HE Yu,CHANG Lili,PAN Zhijun.Diagnostic value of SPECT/CT combined with serum fPSA/tPSA in prostate cancer and bone metastasis[J].,2021,50(9):1102-1105.[doi:DOI:10.3969/j.issn.1000-7377.2021.09.015]
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SPECT/CT联合血清游离前列腺特异性抗原/总前列腺特异性抗原检查对前列腺癌及骨转移的诊断价值
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
50
期数:
2021年9期
页码:
1102-1105
栏目:
临床研究
出版日期:
2021-09-05

文章信息/Info

Title:
Diagnostic value of SPECT/CT combined with serum fPSA/tPSA in prostate cancer and bone metastasis
作者:
贺 煜1; 常莉莉2; 潘治军3
(1.延安大学附属医院核医学科,陕西 延安 716000; 2.榆林市星元医院放射科,陕西 榆林 719000; 3.榆林市星元医院骨科,陕西 榆林 719000)
Author(s):
HE Yu; CHANG Lili; PAN Zhijun
(Department of Nuclear Medicine,Affiliated Hospital of Yan'an University,Yan'an 716000,China)
关键词:
前列腺癌;  骨转移;  单光子发射计算机断层成像/计算机断层扫描;  游离前列腺特异性抗原;  总前列腺特异性抗原;  诊断价值
Keywords:
Prostate cancer;  Bone metastasis;  SPECT/CT;  Free prostate specific antigen;  Total prostate specific antigen;  Diagnostic value
分类号:
R 737.25
DOI:
DOI:10.3969/j.issn.1000-7377.2021.09.015
文献标志码:
A
摘要:
目的:探讨单光子发射计算机断层成像/计算机断层扫描(SPECT/CT)联合血清游离前列腺特异性抗原(fPSA)/总前列腺特异性抗原(tPSA)检查对前列腺癌及骨转移的诊断价值。方法:选取73例前列腺疾病患者,给予SPECT/CT及血清fPSA/tPSA检查,判断两者在前列腺癌诊断及骨转移中的诊断效果。结果:在73例患者中,病理诊断为前列腺癌33例(前列腺癌组),前列腺增生40例(前列腺增生组)。SPECT/CT检查中,前列腺癌组最大标准摄取值(SUVmax)与平均标准摄取值(SUVmean)高于前列腺增生组(均P<0.05)。前列腺癌组血清fPSA与tPSA水平高于前列腺增生组(均P<0.05)。SPECT/CT、fPSA/tPSA诊断前列腺癌的敏感度与特异度都在60.0%以上,两者联合诊断的敏感性与特异性在80.0%以上。Pearson相关性分析显示,前列腺癌骨转移与SUVmax、SUVmean、fPSA、tPSA呈正相关(均P<0.05)。结论:SPECT/CT联合血清fPSA/tPSA检查对前列腺癌及骨转移具有良好的诊断价值。
Abstract:
Objective:To explore the diagnostic value of SPECT/CT combined with serum fPSA/tPSA in prostate cancer and bone metastasis.Methods:73 patients with prostate diseases were examined by SPECT/CT and serum fPSA/tPSA to judge the diagnostic value of both in prostate cancer and bone metastasis.Results:Among the 73 patients,33 cases were diagnosed as prostate cancer(prostate cancer group)and 40 cases as prostatic hyperplasia(prostatic hyperplasia group).In SPECT/CT examination,SUVmax and SUVmean in prostate cancer group were higher than those in prostatic hyperplasia group(all P<0.05).The serum levels of fPSA and tPSA in prostate cancer group were higher than those in prostatic hyperplasia group(all P<0.05).The sensitivity and specificity of SPECT/CT and fPSA/tPSA in the diagnosis of prostate cancer were more than 60.0%,and the sensitivity and specificity of the combined diagnosis were more than 80.0%.Pearson correlation analysis showed that bone metastasis of prostate cancer was positively correlated with SUVmax,SUVmean,fPSA and tPSA(all P<0.05).Conclusion:SPECT/CT combined with serum fPSA/tPSA has good diagnostic value for prostate cancer and bone metastasis.

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备注/Memo

备注/Memo:
基金项目:陕西省重点研发计划项目(2021SF-252)
更新日期/Last Update: 2021-09-06