[1]李陇超,严雪娇,杨艳蓉,等.多参数磁共振成像膀胱影像报告和数据系统评分对肌层浸润性膀胱癌诊断价值研究[J].陕西医学杂志,2021,50(2):180-183.[doi:DOI:10.3969/j.issn.1000-7377.2021.02.014]
　LI Longchao,YAN Xuejiao,YANG Yanrong,et al.Diagnostic value of multiparametric MRI using VI-RADS score for muscle invasive urinary bladder cancer[J].,2021,50(2):180-183.[doi:DOI:10.3969/j.issn.1000-7377.2021.02.014]
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多参数磁共振成像膀胱影像报告和数据系统评分对肌层浸润性膀胱癌诊断价值研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
50
期数:
2021年2期
页码:
180-183
栏目:
临床研究
出版日期:
2021-02-05

文章信息/Info

Title:
Diagnostic value of multiparametric MRI using VI-RADS score for muscle invasive urinary bladder cancer
作者:
李陇超1; 2; 严雪娇1; 杨艳蓉1; 常鸿志1; 雷晓燕1; 张小玲1; 段小艺2; 张 沥1
(1.陕西省人民医院磁共振室,陕西 西安 710068; 2.西安交通大学第一附属医院影像中心,陕西 西安 710061)
Author(s):
LI Longchao; YAN Xuejiao; YANG Yanrong; CHANG Hongzhi; LEI Xiaoyan; ZHANG Xiaoling; DUAN Xiaoyi; ZHANG Li
(Department of MRI,Shaanxi Provincial People's Hospital,Xi'an 710068,China)
关键词:
多参数磁共振成像;  膀胱影像报告和数据系统;  肌层浸润性膀胱癌;  诊断
Keywords:
Multiparametric magnetic resonance imaging;  Vesical imaging-reporting and data system;  Muscle invasive bladder cancer;  Diagnosis
分类号:
R 737.1
DOI:
DOI:10.3969/j.issn.1000-7377.2021.02.014
文献标志码:
A
摘要:
目的:探讨多参数磁共振成像膀胱影像报告和数据系统(VI-RADS)评分对肌层浸润性膀胱癌的诊断效能。方法:回顾性分析经病理证实的膀胱癌172例,所有患者术前均接受多参数MRI检查,包括T2WI加权成像、扩散加权成像(DWI)和动态增强成像(DCE)。两位放射科医生根据VI-RADS对多参数MRI图像进行独立评分,通过达成共识解决争议。将VI-RADS得分与病理结果比较,计算不同VI-RADS截断值的敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV),绘制受试者工作特征曲线(ROC)分析VI-RADS 评分对肌层浸润性膀胱癌的诊断效能。结果:172例患者中,病理证实为肌层浸润性膀胱癌54例,非肌层浸润性膀胱癌118例。以VI-RADS≥3分作为截断值预测肌层浸润性膀胱癌,约登指数最大,为0.764,敏感性为81.5%,特异性为94.9%,PPV为88.0%,NPV为91.8%; ROC曲线分析显示,曲线下面积(AUC)为0.921(95%CI:0.873～0.969,P<0.001)。结论:多参数磁共振成像VI-RADS评分能准确预测肌层浸润性膀胱癌,有助于膀胱癌治疗决策制定。
Abstract:
Objective:To investigate the diagnostic efficacy of multiparameter magnetic resonance imaging(MRI)using vesical imaging-reporting and data system(VI-RADS)for muscle invasive bladder cancer.Methods:172 patients with bladder cancer confirmed by pathology were retrospectively analyzed.All patients underwent multiparameter MRI before surgery,including T2WI weighted imaging,diffusion weighted imaging(DWI)and dynamic enhanced imaging(DCE).Two radiologists evaluated the multiparametric MRI images independently according to VI-RADS,and disparities were resolved through consensus.The VI-RADS score was compared with the pathological results,and the sensitivity,specificity,positive predictive value(PPV)and negative predictive value(NPV)of different VI-RADS cut-off values were calculated.The receiver operating characteristic(ROC)curve was used to analyze the diagnostic power of VI-RADS score for muscle invasive bladder cancer.Results:Among the 172 patients,118 with nonmuscle invasive bladder cancer and 54 with muscle invasive bladder cancer.Using VI-RADS ≥ 3 as the cut-off value to predict muscle invasive bladder cancer,the Youden index was the largest(0.764),sensitivity was 81.5%,specificity was 94.9%,PPV was 88.0%,NPV was 91.8%.ROC curve Analysis showed that the area under the curve(AUC)was 0.921(95%CI:0.873-0.969,P<0.001).Conclusion:The VI-RADS score can effectively predict muscle invasive bladder cancer,which is helpful for the decision making of bladder cancer treatment.

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备注/Memo

备注/Memo:
基金项目:陕西省重点研发计划项目(2018SF-169)
更新日期/Last Update: 2021-01-28