[1]李建华,李宁侠,陶绍辉△,等.未成年人2552例体内镉、铜、铁、铅、锌、钙、镁元素水平调查研究*[J].陕西医学杂志,2020,49(12):1691-1694.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.041]
　LI Jianhua,LI Ningxia,TAO Shaohui,et al.Investigation and analysis of cadmium,copper,iron,lead,zinc,calcium and magnesium in 2552 minors[J].,2020,49(12):1691-1694.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.041]
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未成年人2552例体内镉、铜、铁、铅、锌、钙、镁元素水平调查研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年12期
页码:
1691-1694
栏目:
调查研究
出版日期:
2020-12-05

文章信息/Info

Title:
Investigation and analysis of cadmium,copper,iron,lead,zinc,calcium and magnesium in 2552 minors
作者:
李建华1; 李宁侠1; 陶绍辉1△; 王海东1; 姜海迪2; 王晓琴3; 宁玉洁4
1.西安医学院第二附属医院检验科(西安 710038); 2.兰州市第一人民医院检验科(兰州 730050); 3.西安交通大学第一附属医院检验科(西安 710061); 4.西安交通大学公共卫生学院地方病研究所(西安 710061)
Author(s):
LI Jianhua; LI Ningxia; TAO Shaohui; et al.
Department of Clinical Laboratory,the Second Affiliated Hospital of Xi'an Medical University(Xi'an 710038)
关键词:
未成年人;  微量元素;  宏量元素;  分布特点;  回顾性分析;  生长发育
Keywords:
Minors;  Microelement;  Macroelement;  Distribution characteristics;  Retrospective analysis;  Growing development
分类号:
R446.11
DOI:
DOI:10.3969/j.issn.1000-7377.2020.12.041
文献标志码:
A
摘要:
目的:了解未成年人体内微量元素(镉、铜、铁、铅、锌)和宏量元素(钙、镁)水平,探讨其在不同性别和年龄段人群中分布特点,对综合防治未成年人体内7种元素缺乏或过量提供科学依据。方法:回顾性分析2552例未成年人血液中镉、铜、铁、铅、锌、钙和镁的检测结果,按照未成年人生长发育特点分为八组:0～6个月组(350例),6～12个月组(930例),1～1.5岁组(345例),1.5～2岁组(277例),2～3岁组(227例),3～6岁组(226例),6～10岁组(128例),10～17岁组(69例)。各元素检测采用原子吸收分光光度法。应用SPSS 19.0统计学软件对数据进行分析。结果:各年龄组人群铜和镁水平异常率很低; 铅和镉的过量病例主要集中于6岁以上人群。7种元素中水平异常以钙、铁、锌为主,呈缺乏和过量并存现象,但以缺乏为主,且随年龄增大,缺乏率和过量率均呈下降态势,但在0～6个月组婴幼儿,三者缺乏较明显。各年龄组未成年人体内血镁含量比较无统计学差异(P>0.05),而铁、锌、钙、铅、镉、铜水平比较差异均有统计学意义(均P<0.05)。其中,铅、镉、铁、锌随着年龄增大而升高,而钙、铜随着年龄增大而降低。不同性别未成年人群体内镉、镁、锌元素水平比较无统计学差异(P>0.05); 在男性体内铜、铁、铅元素水平较女性高,而钙元素水平较女性低(均P<0.05)。结论:镉、铜、铁、铅、锌、钙和镁元素失衡在未成年人群中普遍存在,应定期到医疗机构进行元素检测,必要时采取干预措施。
Abstract:
Objective:To understand the levels of microelements(cadmium,copper,iron,lead,zinc)and macroelements(calcium,magnesium)in minors,and to explore their distribution characteristics in different gender and age groups,so as to provide scientific basis for comprehensive prevention and treatment of seven elements deficiency or excess in minors.Methods:A retrospective analysis was made on the results of blood cadmium,copper,iron,lead,zinc,calcium and magnesium in 2552 minors.According to their growth and development characteristics,the minors were divided into eight groups:0-6 months group(350 cases),6-12 months group(930 cases),1-1.5 years group(345 cases),1.5-2 years group(277 cases),2-3 years group(227 cases),3-6 years group(226 cases),6-10 years group(128 cases)and 10-17 years group(69 cases).All elements were detected by atomic absorption spectrophotometry.SPSS 19.0 was used to analyze the data.Results:The abnormal rates of copper and magnesium levels were very low in all age groups; the excessive cases of lead and cadmium were mainly concentrated in minors over 6 years old.The results showed that calcium,iron and zinc were the main abnormal elements in the 7 kinds of elements,which coexisted with deficiency and excess,but deficiency was the main factor.The deficiency rate and excess rate decreased with the increase of age.However,in the 0-6 months group,the deficiency of the three elements was more obvious.There was no significant difference in blood magnesium level among different age groups(P>0.05),but there were significant differences in iron,zinc,calcium,lead,cadmium and copper levels(all P<0.05).Among them,lead,cadmium,iron and zinc increased with age,while calcium and copper decreased with age.There was no significant difference in the levels of cadmium,magnesium and zinc among different gender groups(P>0.05); the levels of copper,iron and lead in male were higher than those in female,while the levels of calcium were lower than those in female(all P<0.05).Conclusion:The imbalance of cadmium,copper,iron,lead,zinc,calcium and magnesium is common in minors.We should check the elements in medical institutions regularly and take intervention measures when necessary.

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备注/Memo

备注/Memo:
*国家自然科学基金青年科学基金资助项目(81803178)
更新日期/Last Update: 2020-12-11