[1]杨 进,荔 琦,常春峰△.脊柱骨质疏松骨折患者椎体成形术后再骨折发生率及危险因素研究*[J].陕西医学杂志,2020,49(12):1573-1576.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.009]
　YANG Jin,LI Qi,CHANG Chunfeng..Incidence and risk factors of refracture after percutaneous vertebroplasty in patients with spinal osteoporotic fractures[J].,2020,49(12):1573-1576.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.009]
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脊柱骨质疏松骨折患者椎体成形术后再骨折发生率及危险因素研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年12期
页码:
1573-1576
栏目:
临床研究
出版日期:
2020-12-05

文章信息/Info

Title:
Incidence and risk factors of refracture after percutaneous vertebroplasty in patients with spinal osteoporotic fractures
作者:
杨 进; 荔 琦; 常春峰△
陕西中医药大学附属医院骨创伤一科(咸阳 712000)
Author(s):
YANG Jin; LI Qi; CHANG Chunfeng.
Department of Bone Trauma,Affiliated Hospital of Shaanxi University of Chinese Medicine(Xianyang 712000)
关键词:
脊柱骨折;  骨质疏松;  椎体成形术;  再骨折;  发生率;  危险因素
Keywords:
Spinal fracture;  Osteoporosis;  Percutaneous vertebroplasty;  Refracture;  Incidence;  Risk factor
分类号:
R683.2
DOI:
DOI:10.3969/j.issn.1000-7377.2020.12.009
文献标志码:
A
摘要:
目的:探讨脊柱骨质疏松骨折患者椎体成形术(PVP)后再骨折发生率及危险因素。方法:回顾性分析110例脊柱骨质疏松骨折患者临床资料,所有患者均行PVP手术。记录患者术后1年内再骨折情况,对再骨折组与未再骨折组临床资料进行单因素分析,通过Logistic回归分析术后再骨折危险因素。结果:110例患者共136个椎体均顺利进行了PVP手术,随访1年后有24例共28个椎体出现非手术椎体再骨折,发生率约21.82%,其中邻近椎体骨折14例(58.33%),非邻近椎体骨折10例(41.67%)。Logistic回归分析显示,既往骨折病史、骨水泥渗漏、年龄、椎体高度恢复率、术后Cobb角、手术强化椎体数、骨密度T值是影响脊柱骨质疏松骨折患者PVP术后再骨折的影响因素。再骨折患者中相邻椎体组与远隔椎体组性别、既往骨折病史、骨折类型、骨水泥渗漏、年龄、椎体高度恢复率、术后Cobb角、手术强化椎体数、骨密度T值比较,差异无统计学意义(P>0.05)。结论:脊柱骨质疏松骨折患者PVP术后再骨折危险因素较多,临床上应针对性给予抗骨质疏松治疗。
Abstract:
Objective:To explore the incidence and risk factors of refracture after percutaneous vertebroplasty(PVP)in patients with spinal osteoporotic fractures.Methods:A retrospective analysis was performed on 110 patients with spinal osteoporotic fractures.All patients had underwent PVP.The refracture situations of patients within 1 year after surgery were recorded.Univariate analysis was conducted on the clinical data in refracture group and non-refracture group.Logistic regression analysis was conducted for the risk factors of postoperative refracture.Results:All the 110 patients(136 vertebrae)had underwent PVP successfully.After 1-year follow-up,there were 24 cases(28 vertebrae)with non-surgical vertebral refractures(about 21.82%),including 14 cases with adjacent vertebral fractures,accounting for 58.33%,and 10 cases with non-adjacent vertebral fractures,accounting for 41.67%.Logistic regression analysis showed that previous fractures history,bone cement leakage,age,restoration rate of vertebral height,postoperative Cobb angle,number of surgery-strengthened vertebrae and T value of bone mineral density were influencing factors of refracture after PVP for spinal osteoporotic fractures.Among the patients with refractures,the differences in gender,previous fractures history,fracture types,bone cement leakage,age,restoration rate of vertebral height,postoperative Cobb angle,number of surgery-strengthened vertebrae and T value of bone mineral density were not statistically significant between adjacent vertebrae group and distant vertebrae group(P>0.05).Conclusion:The risk factors of refracture after PVP for spinal osteoporotic fractures are many.Clinically,targeted anti-osteoporosis treatment should be given.

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备注/Memo

备注/Memo:
*陕西省科学技术研究发展计划项目(2017ZDXM-SF-009)
更新日期/Last Update: 2020-12-11