[1]赖敬波,李晓苗,赵国宏,等.肥胖人群下肢肌肉含量及其与内脏脂肪型肥胖关系研究*[J].陕西医学杂志,2020,49(12):1566-1568,1572.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.007]
　LAI Jingbo,LI Xiaomiao,ZHAO Guohong,et al.Study on the relationship between lower limb muscle content and visceral adiposity in obese population[J].,2020,49(12):1566-1568,1572.[doi:DOI:10.3969/j.issn.1000-7377.2020.12.007]
点击复制

肥胖人群下肢肌肉含量及其与内脏脂肪型肥胖关系研究*
分享到：

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年12期
页码:
1566-1568,1572
栏目:
临床研究
出版日期:
2020-12-05

文章信息/Info

Title:
Study on the relationship between lower limb muscle content and visceral adiposity in obese population
作者:
赖敬波1; 李晓苗1; 赵国宏2; 景晓锐2; 张麦叶1; 王 琼1; 王晓光2△
1.空军军医大学西京医院内分泌代谢科(西安 710032); 2.空军军医大学唐都医院内分泌科(西安 710038)
Author(s):
LAI Jingbo; LI Xiaomiao; ZHAO Guohong; et al.
Department of Endocrinology and Metabolism,Xijing Hospital,Air Force Medical University(Xi'an 710032)
关键词:
肥胖;  人体成分分析;  双下肢肌肉含量;  内脏脂肪
Keywords:
Adipositas;  Body composition analysis;  Muscle mass of both lower limbs;  Visceral fat
分类号:
R723.14
DOI:
DOI:10.3969/j.issn.1000-7377.2020.12.007
文献标志码:
A
摘要:
目的:探讨肥胖人群肌肉分布特点及其与内脏脂肪型肥胖的关系。方法:采用InBody720多频生物电阻抗分析仪对2318例成人进行人体成分分析。按体重指数(BMI)不同将受试者分为正常组、超重组及肥胖组,分析各组人群肌肉量特点及其与内脏脂肪的关系,并确定肌肉量指标与内脏脂肪型肥胖(以内脏脂肪面积>100 cm2作为的诊断标准)的最佳切点。结果:除双上肢肌肉量/体重之外,其他数据在三组间比较均有统计学差异(P<0.05)。将双下肢肌肉量/体重与肥胖相关指标进行分析显示,校正了年龄和性别后,内脏脂肪含量与腰臀比、体脂率呈正相关(r=0.720、0.843,均P<0.05),与双上肢肌肉量/体重、双下肢肌肉量/体重均呈负相关(r=-0.557、-0.880,均P<0.05)。双下肢肌肉量/体重预测内脏脂肪型肥胖(内脏脂肪面积>100 cm2)的ROC曲线下面积为0.922。以最大约登指数确定切点,当下肢肌肉量/体重为0.2115时,对内脏脂肪型肥胖诊断的敏感性为85.6%,特异性为82.8%。结论:双下肢肌肉量/体重可作为评价内脏脂肪型肥胖的潜在有效指标。
Abstract:
Objective:To investigate the association between distribution characteristics of muscle and visceral obesity in obese population.Methods:The human body composition of 2318 adults was analyzed by inbody720 multi frequency bioelectrical impedance analyzer.According to different body mass index(BMI),the subjects were divided into normal group,overweight group and obesity group.The characteristics of muscle mass and the relationship between visceral fat and muscle mass index were analyzed,and the optimal cut-off point between muscle mass index and visceral fat obesity(visceral fat area >100 cm2)was determined.Results:Except for the muscle mass of both upper limbs/body weight,other data were statistically different among the three groups(P<0.05).After adjusting for age and gender,visceral fat content was positively correlated with waist hip ratio and body fat rate(r=0.720、0.843,all P<0.05),and negatively correlated with upper limb muscle mass / body weight,lower limb muscle mass/body weight(r=-0.557、-0.880,all P<0.05).The area under the ROC curve for predicting visceral fat obesity(visceral fat area >100 cm2)was 0.922.When the muscle mass of lower limbs/body weight was 0.2115,the sensitivity and specificity of diagnosing visceral adiposity were 85.6% and 82.8%,respectively.Conclusion:Muscle mass of both lower limbs/body weight can be used as a potential effective index to evaluate visceral fat obesity.

参考文献/References:

[1] Malafarina V,Uriz-Otano F,Iniesta R,et al.Sarcopenia in the elderly:diagnosis,physiopathology,and treatment[J].Maturitas,2012,71(2):109-114.
[2] 汪孟真,孙少俐.老年人肌少性肥胖研究进展[J].中国实用医药,2019,14(1):197-198.
[3] 毛维维,伊桂叶.不同肥胖类型患者血清代谢指标与内脏脂肪指数的相关性分析[J].现代检验医学杂志,2019,34(5):1-3,8.
[4] 中国肥胖问题工作组数据汇总分析协作组.我国成人体重指数和腰围对相关疾病危险因素异常的预测价值:适宜体重指数和腰围切点的研究[J].中华流行病学杂志,2002,23(1):5-10.
[5] Oda E.New criteria for ‘obesity disease' in Japan[J].Circ J,2002,66:987-992.
[6] 王昌军,尹 宏.肌肉组织和脂肪组织对绝经后女性骨密度及骨强度的影响及作用机制[J].中国骨质疏松杂志,2019,25(10):1502-1508.
[7] 贺秀华,田 刚.腹型肥胖成人患者内脏脂肪分布与冠状动脉损伤的关系[J].中华实用诊断与治疗杂志,2018,32(1):50-53.
[8] 张洪明,宇克莉,魏 榆,等.羌族成人肥胖指标与内脏脂肪等级的关系[J].天津师范大学学报:自然科学版,2018,38(4):73-76.
[9] 佟 欣,李 磊,郑 强,等.肥胖者减肥前后血脂、血压、血糖及血清胰岛素的变化[J].陕西医学杂志,2008,37(12):1625-1627.
[10] 杨 铮,黄 萍,杨 阳,等.西安地区中老年人血清尿酸检测的临床价值研究[J].陕西医学杂志,2019,48(7):951-953.
[11] 许晓英,杨 琳,杨得花,等.产褥期女性体成分现况研究[J].中国妇幼保健,2019,34(8):1725-1727.
[12] 庞 坚,曹月龙,石印玉,等.女性膝骨关节炎患者体质参数和肌肉功能状态的对照研究[J].中国骨伤,2008,21(11):828-830.
[13] Prado CM,Wells JC,Smith SR,et al.Sarcopenic obesity:a critical appraisal of the current evidence[J].Clin Nutr,2012,31(5):583-601.
[14] Cruz-Jentoft AJ,Bahat G,Bauer J,et al.Sarcopenia:revised European consensus on definition and diagnosis[J].Age Ageing,2019,48(1):16-31.
[15] Lu CW,Yang KC,Chang HH,et al.Sarcopenic obesity is closely associated with metabolic syndrome[J].Obes Res Clin Pract,2013,7(4):301-307.
[16] Srikanthan P,Hevener AL,Karlamangla AS. Sarcopenia exacerbates obesity-associated insulin resistance and dysglycemia:findings from the National Health and Nutrition Examination Survey Ⅲ[J].PLoS One,2010,5(5):e10805.
[17] Lim S,Kim JH,Yoon JW,et al.Sarcopenicobesity:prevalence and association with metabolic syndrome in the Korean longitu-dinal study on health and aging(KLoSHA)[J].Diabetes Care,2010,33(7):1652-1654.
[18] Berit LH,Peder F.Thigh circumference and risk of heart disease and premature death:prospective cohort study[J].BMJ,2009,339:b3292.

相似文献/References:

[1]王玲,尹春燕,肖延风,等.代谢紊乱及细胞因子对肥胖儿童血压的影响[J].陕西医学杂志,2016,(10):1373.
[2]高阿宁.儿童肥胖指数与血脂及心率变异性临床研究*[J].陕西医学杂志,2019,(1):19.
　GAO A'ning..Clinical research between childhood obesity index and blood lipid and heart rate variability[J].,2019,(12):19.
[3]郑锦标,马萍萍,马瑞倩.糖尿病伴发视网膜微血管异常临床特征及危险因素调查研究[J].陕西医学杂志,2019,(11):1571.
[4]刘岩松,祁 烁,张 洁,等.660 nm激光照射对肥胖小鼠代谢的影响实验研究[J].陕西医学杂志,2024,(6):759.[doi:DOI:10.3969/j.issn.1000-7377.2024.06.008]
　LIU Yansong,QI Shuo,ZHANG Jie,et al.Effects of 660 nm laser irradiation on metabolism in obese mice[J].,2024,(12):759.[doi:DOI:10.3969/j.issn.1000-7377.2024.06.008]

备注/Memo

备注/Memo:
*国家重点研发计划项目(2017YFC1309803)
更新日期/Last Update: 2020-12-11