[1]屈文涛,马 静,康亚宁△,等.二维斑点追踪技术评价不同体质量指数2型糖尿病患者左心房功能[J].陕西医学杂志,2020,49(9):1138-1141.[doi:DOI:10.3969/j.issn.1000-7377.2020.09.021]
　QU Wentao,MA Jing,KANG Yaning,et al.Evaluation of left atrial function in type 2 diabetes patients with different body mass index by two-dimensional speckle tracking technique[J].,2020,49(9):1138-1141.[doi:DOI:10.3969/j.issn.1000-7377.2020.09.021]
点击复制

二维斑点追踪技术评价不同体质量指数2型糖尿病患者左心房功能
分享到：

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年9期
页码:
1138-1141
栏目:
临床研究
出版日期:
2020-09-01

文章信息/Info

Title:
Evaluation of left atrial function in type 2 diabetes patients with different body mass index by two-dimensional speckle tracking technique
作者:
屈文涛; 马 静; 康亚宁△; 苏 洁; 齐 芳; 范丽平
西安市中医医院超声科(西安 710021)
Author(s):
QU Wentao; MA Jing; KANG Yaning; et al.
Department of Ultrasound,Xi'an Hospital of Traditional Chinese Medicine(Xi'an 710021)
关键词:
2型糖尿病;  肥胖;  心血管疾病;  心肌病;  二维斑点追踪技术;  左心房应变
Keywords:
Type 2 diabetes;  Obesity;  Cardiovascular disease;  Cardiomyopathy;  Two-dimensional speckle tracking imaging;  Strain of left atrium
分类号:
R587.1
DOI:
DOI:10.3969/j.issn.1000-7377.2020.09.021
文献标志码:
A
摘要:
目的:探讨应用二维斑点追踪技术评价不同体质量指数(BMI)2型糖尿病患者左心房功能。方法:选取初次诊断2型糖尿病患者110例,根据患者BMI不同分为体质量正常组(BMI≤24 kg/m2,30例)、超重组(24 kg/m22,40例)和肥胖组(BMI≥28 kg/m2,40例)。另外选取30例健康志愿者作为正常对照组。应用二维斑点追踪技术获取心尖四腔切面、二腔切面、三腔切面左心房各节段纵向应变值,分别计算左心室收缩期左心房整体峰值纵向应变(LAS-s)、舒张早期左心房整体纵向应变(LAS-e)、舒张晚期左心房整体纵向应变(LAS-a)。比较四组间各参数的差异。结果:与正常对照组比较,体质量正常组、超重组、肥胖组的LAS-s、LAS-e和LAS-a水平均减低,组间比较差异均有统计学意义(均P<0.05)。超重组LAS-a大于体质量正常组与肥胖组(均P<0.05)。结论:随着BMI增加,2型糖尿病患者左心房心肌功能受损趋严重。超重和肥胖是2型糖尿病患者左心房功能受损的主要因素。二维斑点追踪技术能够早期发现左心房心肌结构和功能的改变情况。
Abstract:
Objective:To analyze left atrial function in type 2 diabetic with different body mass index(BMI)by two-dimensional speckle tracking imaging(2D-STI).Methods:110 type 2 diabetes patients were selected and divided into three group based on the different BMI:normal weight group(BMI≤24 kg/m2,30 subjects),overweight group(24 kg/m22,40 subjects),obesity group(BMI≥28 kg/m2,40 subjects).Another 30 healthy volunteers were selected as the normal control group.The strain of the left atrial segments on the four-chamber section,two-chamber section and three-chamber section of the apex of the heart were calculated by two-dimensional speckle tracking imaging(2D-STI).LA peak ventricular systolic strain(LAS-s),LA peak early-diastolic strain(LAS-e)and LA peak atrial systolic strain(LAS-a)in longitudinal directions of all the subjects were measured by 2D-STI.The differences of parameters among the four groups were compared.Results:Compared with the normal control group,the levels of LAS-s,LAS-e and LAS-a in the normal weight group,the overweight group and the obesity group were all decreased,and the differences between the groups were significant(all P<0.05).The LAS-a of the overweight group was higher than that of the normal weight group and the obesity group(all P<0.05).Conclusion:With the increase of BMI,the myocardial function of left atrium in type 2 diabetes patients tends to be seriously damaged.Overweight and obesity are the main factors of left atrial dysfunction in patients with type 2 diabetes.2D-STI can detect the structural and functional changes of the left atrium in the early stage.

参考文献/References:

[1] 刘章平.体重指数、胰岛素抵抗与肥胖糖尿病前期患者的关系[J].陕西医学杂志,2015,44(9):1202-1204.
[2] Wilding JPH.The importance of weight management in type 2 diabetes mellitus[J].International Journal of Clinical Practice,2014,68(6):682-691.
[3] 杨亚锋,王 萍,王 利,等. 2型糖尿病合并腹型肥胖男性患者胰岛素抵抗与内脏脂肪面积相关性研究[J].陕西医学杂志,2020, 49(6):717-719.
[4] 王庆庆,高云华,夏红梅,等.超声三维斑点追踪技术对肥胖和非肥胖2型糖尿病患者心脏功能的评价[J].中国超声医学杂志,2015,31(5):35-37.
[5] Lehrke M,Marx N.Diabetes mellitus and heart failure[J].The American Journal of Cardiology,2017,120(Suppl):s37-47.
[6] Przewlocka-Kosmala M,Jasic-Szpak E,Rojek A,et al.Association of central blood pressure with left atrial structural and functional abnormalities in hypertensive patients:implications for atrial fibrillation prevention[J].European Journal of Preventive Cardiology,2019,26(10):1018-1027.
[7] Zoroufian A,Razmi T,Taghavi-Shavazi M,et al.Evaluation of subclinical left ventricular dysfunction in diabetic patients:longitudinal strain velocities and left ventricular dyssynchrony by two-dimensional speckle tracking echocardiography study[J].Echocardiography,2014,31(4):456-463.
[8] 屈文涛,康亚宁,许 磊,等.二维斑点追踪技术评价高尿酸血症患者左房功能与心外膜脂肪厚度临床研究[J].陕西医学杂志,2020, 49(4):474-476,505.
[9] 苗 燕.老年 2 型糖尿病肾病并发心脑血管疾病相关危险因素分析[J].陕西医学杂志,2016,45(12):1651-1652.
[10] Ng AC,Delgado V,Bertini M,et al.Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus[J].Circulation,2010,122(24):2538-2544.
[11] 李艳艳,贾 伟.24 h动态心电图在 2 型糖尿病合并冠心病患者心律诊断中的价值分析[J].陕西医学杂志,2019,48(1):61-63.
[12] Mondillo S,Cameli M,Caputo ML,et al.Early detection of left atrial strain abnormalities by speckle-tracking in hypertensive and diabetic patients with normal left atrial size[J].Journal of the American Society of Echocardiography,2011,24(8):898-908.
[13] 刘 俊,郭 毅,刘 晴,等.超重、肥胖与2型糖尿病相关性的Meta分析[J].中国循证医学杂志,2013,13(2):190-195.
[14] 陈伟国,张晓萌,常 盼,等.阿托伐他汀对 2 型糖尿病心肌病患者心功能、脑钠肽、超敏 C 反应蛋白影响临床研究[J].陕西医学杂志,2019,48(1):10-12.
[15] 石艳萍,李一丹,赵智玲,等.二维斑点追踪成像评价阻塞型睡眠呼吸暂停综合征患者左心房功能和同步性[J].中国超声医学杂志,2019,35(1):14-17.
[16] 刘慧兰,董丽莉,颜如玉,等.斑点追踪技术对原发性高血压合并超重及肥胖患者左室心肌收缩功能的评价[J].中国超声医学杂志,2019,35(2):134-136.
[17] Tadic M,Cuspidi C,Ilic I,et al.The relationship between blood pressure variability,obesity and left atrial phasic function in hypertensive population[J].The International Journal of Cardiovascular Imaging,2016,32(4):603-612.
[18] Blomstrand P,Sjöblom P,Nilsson M,et al.Overweight and obesity impair left ventricular systolic function as measured by left ventricular ejection fraction and global longitudinal strain[J].Cardiovascular Diabetology,2018,17(1):113-118.
[19] 刘山俊,甘 玲,尹家保,等.超声心动图评价 2 型糖尿病患者左心房功能的研究进展[J].湖北医药学院学报,2018,32(1):96-100.
[20] Hoit BD.Left atrial size and function:role in prognosis[J].Journal of the American College of Cardiology,2014,63(6):493-505.
[21] Raafat SS,Ramzy AA,Demian H,et al.Assessment of left ventricular systolic function by tissue Doppler imaging in controlled versus uncontrolled type 2 diabetic patients[J].The Egyptian Heart Journal,2018,70(3):203-211.

相似文献/References:

[1]李艳艳,贾 伟△.24h动态心电图在2型糖尿病合并冠心病患者心律诊断中的价值分析[J].陕西医学杂志,2019,(1):61.
[2]郭向东,马 波△.2型糖尿病患者血清胰岛素水平与骨代谢关联研究*[J].陕西医学杂志,2019,(1):77.
　GUO Xiangdong,MA Bo..Association between serum insulin level and bone metabolismin patients with type 2 diabetes mellitus[J].,2019,(9):77.
[3]刘毅龙,陈鹏宇,雷 江,等.SGLT2抑制剂在2型糖尿病合并心血管疾病治疗中的应用研究进展[J].陕西医学杂志,2019,(3):407.
[4]姚爱红.利拉鲁肽治疗2型糖尿病效果及对患者血脂、颈动脉内膜中层厚度的影响[J].陕西医学杂志,2019,(4):518.
　YAO Aihong..Effect of liraglutide on type 2 diabetes mellitus in patients with blood lipids and carotid intimamedia thickness[J].,2019,(9):518.
[5]李忆琴,吴礼凤,余晓君,等.中年2型糖尿病患者病程和HbA1c水平与认知功能相关性研究*[J].陕西医学杂志,2019,(6):722.
[6]徐 琳,贾睿博△,宋民喜,等.颗粒蛋白前体与糖尿病肾病关系探讨*[J].陕西医学杂志,2019,(8):1024.
[7]王荣锋,郁 昊,蒋新建.老年糖尿病患者血清25羟维生素D水平与骨质疏松相关性研究[J].陕西医学杂志,2019,(8):1032.
　WANG Rongfeng,YU Hao,JIANG Xinjian..The relationship between serum 25 hydroxy vitamin D and osteoporosis in elderly diabetic patients[J].,2019,(9):1032.
[8]王 荣,贾爱华,刘新艳 ,等.IGF1及其相关性因素对2型糖尿病并发骨质疏松的影响研究[J].陕西医学杂志,2019,(9):1163.
　WANG Rong,JIA Aihua,LIU Xinyan,et al.The effect of IGF1 and its related factors in type 2 diabetes complicated with osteoporosis[J].,2019,(9):1163.
[9]贾睿博,徐 琳△.2型糖尿病患者下肢血管病变相关危险因素调查研究[J].陕西医学杂志,2019,(11):1567.
[10]郭建强,赵俊宏,张分队,等.2型糖尿病视网膜病变患者血清HbA1c、CysC检测及临床意义*[J].陕西医学杂志,2020,49(5):619.
　GUO Jianqiang,ZHAO Junhong,ZHANG Fendui,et al.Changes of serum HbA1c and CysC in patients with type 2 diabetic retinopathy and their clinical significance[J].,2020,49(9):619.

更新日期/Last Update: 2020-09-02